Clinical trials
Colorectal clinical trials
Below are recruiting colorectal clinical trials, each written for real people, not researchers. We’re tracking 1,227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06059378Recruiting
AI helps diagnose small colon polyps during colonoscopy
This trial uses artificial intelligence to help doctors decide if small polyps found during a colonoscopy are harmless. If the AI confirms a polyp is benign, it may be left in place instead of removed, making the procedure simpler and safer for you.
Montreal, QuebecAges 45–80 - NCT06724133Recruiting
Mouth bacteria and colon polyps study
This study looks at the bacteria in your mouth and how they might be linked to colon polyps. Researchers want to see if certain mouth bacteria affect the body's immune system and increase the risk of polyps.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05133024RecruitingPhase 2
Beetroot juice to help prevent bowel slowdown after colon surgery
This Phase 2 study tests whether drinking beetroot juice can reduce “postoperative ileus,” when the intestines temporarily don’t move normally after colorectal surgery. If it works, it may help you recover bowel function sooner after an elective laparoscopic colon and upper rectum operation.
EdegemAges 18 years+ - NCT06638502RecruitingPhase 1/Phase 2
Testing HRX215 for liver recovery after surgery
This trial tests a drug called HRX215 to see if it is safe and helps the liver recover after surgery to remove colon cancer tumors that have spread to the liver. It is for people who are having either a minor or major liver resection and have a low risk of liver failure.
Baltimore, MarylandAges 18–75 - NCT07588386Recruiting
Early Colonoscopy After Low Rectal Cancer Surgery
This study tests whether doing a colonoscopy (camera exam of the colon) early after surgery for low rectal cancer helps catch a serious complication called anastomotic leakage—when the surgical connection between bowel segments breaks down. Early detection might help prevent severe infections and improve outcomes.
Nanchong, SichuanAges 18–80 - NCT07544784RecruitingPhase 2
AK104 plus radiation for colorectal cancer spread to liver
This study tests a new immunotherapy drug called AK104 combined with radiation therapy and standard chemotherapy for colorectal cancer that has spread to the liver. The goal is to see if adding AK104 and targeted radiation improves treatment outcomes compared to standard therapy alone.
ShanghaiAges 18 years+ - NCT06763432Recruiting
Colonoscopy readiness study
This study helps patients aged 45–75 at Codman Square Health Center get ready for a colonoscopy to screen for colon cancer. It aims to make the process easier and more comfortable.
Boston, MassachusettsAges 45–75 - NCT07467980Recruiting
Measuring oxygen in the colon during bowel surgery
This study tests a new way to measure oxygen levels inside the colon during surgery, right after the surgeon reconnects the bowel. It may help doctors see if the new connection is healing well.
Nashville, TennesseeAges 18 years+ - NCT07463287Recruiting
Fatty liver and colorectal polyp risk study
This study looks at whether certain gene activity in people with fatty liver disease can predict the risk of developing colorectal polyps. It may help doctors find high-risk patients earlier.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06447727Recruiting
Y-90 beads plus chemo for liver-only colorectal cancer
This trial tests whether adding radioactive Y-90 microspheres (tiny beads that deliver radiation directly to liver tumors) to standard chemo (FOLFIRI and bevacizumab) can help people with advanced colorectal cancer that has spread only to one lobe of the liver, when the first treatment stopped working. The goal is to slow down tumor growth.
Nanjing, JiangsuAges 18–75 - NCT06590259RecruitingPhase 2
Ablation plus drug therapy for colorectal cancer liver metastases
This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.
ShanghaiAges 18–75 - NCT07392268Recruiting
Testing AI to help during endoscopic surgery
This trial tests an AI system to help guide doctors during a minimally invasive procedure to remove early-stage lesions in the esophagus, stomach, or colon. If you're scheduled for this surgery, the AI may help make it safer and more precise.
Hong KongAges 18–85 - NCT07176715Recruiting
Same-day discharge after robotic colon surgery: is it safe?
This study tests whether it is safe for patients to go home the same day after robotic colon surgery. If you are healthy enough and have help at home, you may be able to recover there instead of staying in the hospital overnight.
Phoenix, ArizonaAges 18–70 - NCT02886104Recruiting
Surgery versus local ablation for certain liver metastases
This trial compares two ways to treat colorectal cancer that has spread to the liver: removing liver tumors with surgery versus destroying them in place with local ablation. It may help doctors learn which approach works best for people whose disease can be fully treated and who have enough healthy liver left.
Guangzhou, GuangdongAges 18–80 - NCT04491929Recruiting
Radiation treatment for colon cancer in the liver using tiny beads
This trial studies a targeted liver radiation procedure that uses tiny radioactive beads to treat colon cancer spread mostly in the liver. It may help people whose liver tumors cannot be removed or treated with other common local treatments, but it has several safety and “screening” checks.
Aarhus N, DanmarkAges 18 years+ - NCT07346066RecruitingPhase 3
A trial of IS-001 injection for robotic colorectal surgery
This trial tests an injection called IS-001 during robotic-assisted colorectal surgery. It may help surgeons see the ureters more clearly, which could reduce the risk of injury.
Newport Beach, CaliforniaAges 16–75 - NCT06879912Recruiting
Study of force feedback tools in robot-assisted surgery
This trial tests new force feedback instruments in the da Vinci 5 robot during surgery. It aims to see if they help surgeons perform procedures more precisely for conditions like cancer or other diseases.
Miami, FloridaAges 22 years+ - NCT07215000RecruitingPhase 4
Better Colonoscopy Prep Options for Comfort
This trial compares different colonoscopy prep methods to see which one patients tolerate best. It aims to make the cleaning process before a colonoscopy more comfortable and acceptable.
Atlanta, GeorgiaAges 18 years+ - NCT06549907Recruiting
Study of double immunotherapy plus anti-angiogenic therapy
This trial studies people with certain types of colorectal or other solid tumors that did not respond to a single immunotherapy drug. It tests whether adding a second immune checkpoint blocker and an anti-angiogenic drug can help control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06819280Recruiting
Immune cells for advanced colorectal cancer after first treatment
This trial tests whether your own immune cells, called tumor-infiltrating lymphocytes (TILs), can be grown in a lab and given back to you to fight advanced colorectal cancer. It is for people whose cancer has continued to grow after their first round of chemotherapy.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07541924Recruiting
Image-Guided Colonoscopy: Patient Experience and Doctor Efficiency
This study tests whether using CT scan images to guide doctors during colonoscopy (a camera exam of your colon) improves how well the procedure goes and reduces doctor stress. You'll answer questions about your experience before and after the procedure.
Beijing, Beijing MunicipalityAges 18–80 - NCT07204574RecruitingPhase 1/Phase 2
New drug combo for advanced colorectal cancer after first treatment
This trial tests a new drug combination for advanced colorectal cancer that has not gotten better with standard chemotherapy. It is for people whose tumors have normal RAS and BRAF genes, and it adds a new type of medicine (HCB101) to a common chemotherapy plus targeted therapy regimen.
TaoyuanAges 18 years+ - NCT06816407RecruitingPhase 3
Prucalopride for bowel recovery after colorectal surgery
This trial tests if different doses of prucalopride, a medicine that helps the bowels move, can speed up gut function recovery after planned (not emergency) colorectal surgery.
CairoAges 18–75 - NCT06982872Recruiting
AI-assisted scope test for colorectal growths
This trial tests how well different artificial intelligence tools can help doctors see and diagnose growths in the colon during a special type of scope exam. It may help find better ways to detect polyps and other lesions.
Changchun, JilinAges Any age
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Common questions
- Are there clinical trials for colorectal?
- Yes. Clin2 currently lists 1,227 recruiting colorectal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.