Clinical trials
Colorectal clinical trials
Below are recruiting colorectal clinical trials, each written for real people, not researchers. We’re tracking 1,202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07782164Recruiting
Irreversible electroporation for recurrent pelvic tumors
This study tests a new technique called irreversible electroporation (IRE) for treating pelvic tumors that have returned despite earlier treatment. IRE uses electrical pulses to destroy cancer cells without surgery, offering a potential option when other local treatments like surgery or radiation are not suitable.
Amsterdam, North HollandAges 18 years+ - NCT07781306Recruiting
Imaging study for liver metastasis surgery
This study looks at how well imaging predicts the outcome of surgery for liver metastases from colorectal or breast cancer. If you are having surgery to remove liver metastases, you may be able to participate.
Wilrijk, AntwerpAges 18 years+ - NCT07766044Recruiting
Comparing two ways to close belly surgery cuts
This study compares two methods of closing the cut made during belly surgery to see which one is less likely to cause a hernia later. It is for people having planned colorectal surgery through a midline incision.
Helsingborg, Skåne CountyAges 18 years+ - NCT06590259RecruitingPhase 2
Ablation plus drug therapy for colorectal cancer liver metastases
This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.
ShanghaiAges 18–75 - NCT07741435Recruiting
Simple blood, urine, and saliva test to find cancer early
This study tests a new way to find cancer by looking at DNA in blood, urine, and saliva. It may help detect cancer earlier and monitor how well treatment works.
Bogotá, Bogota D.C.Ages 18 years+ - NCT07736495RecruitingPhase 2/Phase 3
Alpha-lipoic acid for chemo mouth sores in colorectal cancer
This trial tests if a supplement called alpha-lipoic acid (ALA) can protect against painful mouth sores caused by chemotherapy (FOLFOX-6) in people with colorectal cancer. If you are starting FOLFOX-6 for the first time for colorectal cancer, this study may help reduce treatment side effects.
CairoAges 18 years+ - NCT07723937Recruiting
GelPOINT-assisted removal of colon and rectal polyps
This study tests a new way to remove large or complex colon and rectal polyps using a special port system called GelPOINT Path. If you have polyps that are hard to remove with standard colonoscopy, this approach may help your doctor remove them safely.
Houston, TexasAges 18 years+ - NCT07728019RecruitingPhase 2
New drug combo for untreated colon cancer with liver spread
This trial tests a new combination of drugs (Retlirafusp Alfa, Bevacizumab, and chemotherapy) with or without a short course of radiation for people with colorectal cancer that has spread only to the liver and who have not had any prior treatment. The goal is to see if this approach is safe and effective.
Wuhan, HubeiAges 18–75 - NCT07724223RecruitingPhase 2
Combination targeted therapy for advanced colorectal cancer
This trial tests a combination of two targeted drugs (fruquintinib and a drug that targets EGFR) as a third-line treatment for people with a specific type of colorectal cancer that has not responded to previous therapies. It may offer a new option for patients whose tumors are 'wild-type' for certain genes.
Beijing, Beijing MunicipalityAges 18–75 - NCT06632886Recruiting
AI study to find cancers from your past CT scans
This study uses artificial intelligence to look at CT scans you've already had (without dye) to try and find signs of several types of cancer early. It may help find cancer sooner when it's easier to treat.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07720245Recruiting
Self-health app study for adults in Hong Kong
This trial tests a mobile app that helps you check your own health. It is for adults in Hong Kong who want to use the app to learn about their health and get tips.
Hong KongAges 25–65 - NCT07714538Recruiting
Breath test for detecting gastrointestinal cancers
This study tests whether a simple breath test can help detect different types of gastrointestinal cancers earlier. If you have been recently diagnosed with one of these cancers or have concerning abdominal symptoms but clear test results, your breath may help teach us how to spot these cancers sooner.
Maidstone, KentAges 18 years+ - NCT02222844Recruiting
MRI checks for treatment planning in sigmoid colon cancer
This study uses MRI scans to better plan “curative” treatment (aimed at cure) for sigmoid colon cancer before surgery. It is for people who may still be deciding on the radical (major, curative) treatment plan and who can safely have an MRI.
Huntingdon, CambridgeshireAges 16 years+ - NCT02292641Recruiting
MRI study for repeat pelvic colorectal cancer
This study uses a special MRI to help understand and stage colorectal cancer that has come back in the pelvis. The goal is to improve how doctors make treatment decisions after previous surgery.
OsloAges 16 years+ - NCT02579278Recruiting
Tests blood DNA and scans in early colon cancer surgery
This study looks at a blood test that detects cancer DNA (ctDNA) and compares it with CT scan findings before surgery. It may help doctors understand how aggressive the cancer is and how scan features relate to blood test results.
Margate, KentAges 16 years+ - NCT07702292RecruitingPhase 2
68Ga-BED003 PET scan for certain cancers
This trial tests a new PET imaging agent that targets a protein called FAP, which appears in many solid tumors. The goal is to see if this scan can better find and measure cancer in the body.
Bergamo, LombardyAges 18–79 - NCT07703709Recruiting
Colorectal cancer treatment study in real-world care
This study looks at how well treatments work for colorectal cancer in everyday medical practice. It may help doctors understand which therapies are most effective for people like you.
TaichungAges 20 years+ - NCT06656312Recruiting
EndoAim AI for colon polyp detection
This study tests an artificial intelligence (AI) system called EndoAim that helps doctors find polyps during a colonoscopy. It is for people having a routine colonoscopy with an Olympus endoscope.
Taichung, North Dist.Ages 20 years+ - NCT07675967Recruiting
Blood Cell Changes During Cancer Treatment
This study is for people with solid tumors who are about to start chemotherapy or radiation. It looks at how these treatments affect blood cells and may help doctors understand changes in blood health over time.
Boston, MassachusettsAges 18 years+ - NCT07676461Recruiting
Microbiome study in advanced cancer patients starting immunotherapy
This study looks at the bacteria in your mouth, gut, and tumors to see if they affect how well first-line immunotherapy works. It is for people with advanced stomach, colorectal, breast, cervical, or head-and-neck cancer.
Bogotá, Bogota D.C.Ages 18 years+ - NCT07673861Recruiting
Using ctDNA to find resistance and guide cancer treatment
This trial uses a simple blood test to look for changes in your cancer's DNA that might show why your current treatment stopped working. The results could help your doctor choose your next treatment more precisely.
LondonAges 18 years+ - NCT07676383Recruiting
Better cancer screening with community precision navigation
This trial tests a program to help people at high risk for certain cancers get the free screening tests they need. It aims to make screening easier by providing personalized guidance in the community.
Huaihua, HunanAges 45–74 - NCT05428735Recruiting
Liver-first treatment study for colorectal cancer spread to liver
This trial studies a “liver-first” approach for colorectal cancer that has spread mainly to the liver, to see if it can help more people have the tumor(s) removed or treated. You may be eligible if your liver involvement is too extensive for immediate surgery but could become treatable after a specific plan.
New Haven, ConnecticutAges 18 years+ - NCT06646341Recruiting
Can scan findings predict colorectal cancer spread?
This study looks at whether signs of blood vessel involvement (called EMVI) seen on scans can predict if colorectal cancer spreads to other organs. You might join if you already had surgery to remove the cancer from the colon or rectum and any distant tumors, and your before-surgery scans are available for review.
Basingstoke, HampshireAges 16–100
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Common questions
- Are there clinical trials for colorectal?
- Yes. Clin2 currently lists 1,202 recruiting colorectal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.