Clinical trials
Comorbidity clinical trials
Below are recruiting comorbidity clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06368726Enrolling by invitationPhase 1
Brain stimulation for kids with autism and genetic changes
This trial tests a gentle brain stimulation treatment called tDCS for children with autism or related conditions who also have certain genetic changes. It may help improve symptoms if your child meets the specific health and birth history requirements.
Albuquerque, New MexicoAges 6–11 - NCT07439744Recruiting
Omega-3 for Depression and Obesity
This study tests whether omega-3 fatty acids can improve depression in people with obesity. It looks at how these healthy fats might reduce inflammation and help mood.
Taichung, TaichungAges 18–54 - NCT07255209RecruitingPhase 3
A study of IBI362 for Chinese teens with obesity or overweight
This trial tests a new medicine, IBI362, to help Chinese adolescents lose weight. It may be an option if you are 12 to 17 years old and have obesity or overweight with a related health condition.
Hangzhou, ZhejiangAges 12–18 - NCT07436949RecruitingPhase 1/Phase 2
Study of BBT002 for chronic sinusitis with nasal polyps and asthma
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06906328Recruiting
ADHD and addiction: can cognitive training help?
This study tests whether adding a cognitive remediation program to methylphenidate (a medication for ADHD) improves treatment response in adults who have both ADHD and a substance use or behavioral addiction. It aims to help patients manage symptoms better over the short and medium term.
Brest, Brittany RegionAges 18–99 - NCT06507527Recruiting
Frailty in older adults having outpatient digestive endoscopy
This study looks at frailty in older adults (70+) who are having an outpatient digestive endoscopy. It aims to understand how frailty affects the procedure and recovery.
BarcelonaAges 70–100 - NCT05472922Recruiting
Small stomach bypass surgery for weight loss
This trial compares a “mini” gastric bypass procedure to help with weight loss in adults who qualify for bariatric (weight-loss) surgery. It’s testing whether the approach works well and is safe for people who meet the study requirements.
AlmeloAges 18 years+ - NCT05413122RecruitingPhase 2/Phase 3
Smoking quit support for adults living with HIV in South Africa
This trial tests smoking-cessation interventions to help people living with HIV quit smoking or smoke less. You may be eligible if you smoke, are actively engaged in HIV treatment, and can follow the study for about a year.
Soweto, GautengAges 18 years+ - NCT07748091Recruiting
Brain wave and inflammation markers in shock therapy for depression
This study looks at brain wave patterns and markers of inflammation in people with depression that hasn't improved with other treatments and who are receiving electroconvulsive therapy (ECT, also known as shock therapy). The goal is to understand how these markers might relate to how well ECT works.
Istanbul, BakırköyAges 18–60 - NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07736872Recruiting
Sleep apnea screening in diverse groups
This study is screening people from different backgrounds for obstructive sleep apnea (a condition where breathing stops and starts during sleep). It uses a sleep test and questionnaires to see if you might have it.
Guangzhou, GuangdongAges 18–80 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT07552246RecruitingPhase 4
Acupuncture vs medication for depression and anxiety
This study compares acupuncture with standard medication for reducing depression, anxiety, and related sleep problems. It aims to see if acupuncture is a helpful alternative for people in China who are struggling with these conditions.
Kunshan, JiangsuAges 18–65 - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Chandler, ArizonaAges 18–75 - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Anniston, AlabamaAges 18 years+ - NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT03667846RecruitingPhase 2
Biomarker-guided treatment for drinking and PTSD symptoms
This Phase 2 study tests whether blood/brain “biomarkers” can help choose a treatment plan for people who have alcohol use disorder and PTSD. The goal is to improve outcomes related to drinking and PTSD symptoms compared with a standard approach.
New York, New YorkAges 18–70 - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT04463498Recruiting
Sleep school program for insomnia alongside mental health problems
This trial tests a group “sleep school” program to improve sleep when insomnia happens together with moderate to severe mental health symptoms. It may help you learn practical sleep strategies and improve sleep quality while you’re getting psychiatric care.
BergenAges 18–80 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT04831385Recruiting
CBT-I sleep therapy to improve blood sugar in older adults
This study tests whether a structured therapy for insomnia (CBT-I) can help improve blood sugar control in older adults with type 2 diabetes. It targets people who have both high blood sugar levels and troublesome insomnia, aiming to see if better sleep improves glycemic measurements.
Hong KongAges 60 years+
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Common questions
- Are there clinical trials for comorbidity?
- Yes. Clin2 currently lists 118 recruiting comorbidity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a comorbidity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a comorbidity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.