Clinical trials
Congenital Anomalies clinical trials
Below are recruiting congenital anomalies clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06921733Recruiting
Ultrasound study for children with kidney and urinary birth defects
This trial uses a special ultrasound technique to create detailed images of blood flow in the kidneys of children with congenital kidney and urinary tract conditions. It aims to improve how doctors assess blockages without needing radiation.
Erlangen, BavariaAges birth–6 years - NCT04661072Recruiting
Study genes and cancer risk in uterine birth differences
This study looks at how genetic factors and environment may relate to cancer risk in people with uterine birth differences. It also aims to improve clinical care by learning what patterns show up in real-world patients.
New Haven, ConnecticutAges 13 years+ - NCT03723564RecruitingPhase 1
Serial amnioinfusions for severe fetal kidney underdevelopment
This Phase 1 study tests whether repeatedly adding fluid into the amniotic sac (amnioinfusion) can help babies with very severe kidney problems before birth. The goal is to see if this “regenerative therapy” is safe and potentially beneficial, while closely tracking pregnancy and baby outcomes.
Rochester, MinnesotaAges Any age - NCT03398629Recruiting
Study of babies with slow growth or birth defects
This trial looks at how to diagnose and manage pregnancies and babies affected by slow growth before birth, birth defects, or chromosome-related conditions. It may help by improving how doctors confirm problems and plan care for mothers and newborns.
Guangzhou, GuangdongAges Up to 18 years - NCT03059420Recruiting
Genetic study of strabismus and certain birth eye-movement disorders
This study looks for genetic (inherited DNA) causes of strabismus (eyes that don’t line up) and certain birth conditions that affect eye movement and brainstem/cranial nerves. Your participation may help researchers better understand these conditions and guide future testing and care.
Boston, MassachusettsAges 1 day+ - NCT05329935Recruiting
Registry for children with congenital thymus missing
This registry follows children born with congenital athymia (a missing or non-working thymus). It collects information around treatment with RETHYMIC, which may help researchers better understand how care and outcomes look over time.
Durham, North CarolinaAges birth–21 years - NCT05318222Recruiting
Virtual genetic evaluation for undiagnosed rare disease
This study helps children who have a rare genetic illness but have not yet received a diagnosis. It uses virtual evaluation to try to find answers and possible next steps for care.
Edinburg, TexasAges 1 day–18 years - NCT06728007Recruiting
Horseshoe kidney study in children
This study follows children with a horseshoe kidney to understand how the condition affects kidney health and to identify any related birth defects. It may help researchers learn more about this condition and improve care.
Bologna, BolognaAges Up to 18 years - NCT06820892Recruiting
Quality of information during prenatal talks
This trial looks at how well doctors share information with parents before birth, especially when a baby is expected to need special care after delivery. It may help improve how future families are supported.
BronAges 18 years+ - NCT01087320Recruiting
Genetic testing study to find causes of rare disorders
This study uses genome (DNA) sequencing to look for the genetic cause of rare disorders, especially when the cause is unknown. It may help some families better understand what is driving the condition, using genetic information from the affected person and often their parents.
Bethesda, MarylandAges 4 weeks–99 years - NCT02395497RecruitingPhase 2/Phase 3
Penile transplant trial using immune-suppressing medicines
This study tests whether a donated penis can be successfully transplanted using medicines that calm the immune system to prevent rejection. It also looks at safety and recovery of function in men with severe penile loss from injury, cancer surgery, or birth conditions.
Baltimore, MarylandAges 18–69 - NCT07561957Recruiting
Smartphone app to help manage chronic kidney disease
This study tests a smartphone app designed to help people with chronic kidney disease (CKD)—a condition where the kidneys don't filter blood as well as they should—follow the latest medical guidelines. The app aims to make it easier for younger adults to stay on top of their kidney health and treatment.
DublinAges 16–30 - NCT04747626Recruiting
Stent-based repair for damaged upper aorta segments
This trial studies a specific surgical approach using branched stents to repair multiple damaged parts of the upper (thoracic) aorta. It may help people who need urgent or complex aortic repair and are expected to survive more than two years.
Cleveland, OhioAges 18 years+ - NCT06349668RecruitingPhase 3
Comparing spinal morphine and IV lidocaine for robotic kidney surgery
This trial compares two ways to manage pain during robotic-assisted kidney or ureter surgery: a spinal injection of morphine or an intravenous infusion of lidocaine. The goal is to see which method provides better pain relief and recovery.
KalmarAges 18 years+ - NCT02505464Recruiting
Pregnancies with baby birth differences
This study looks at pregnancies that are considered high-risk because the baby is affected by a difference found during pregnancy or at birth. It may help researchers understand and improve care for families dealing with these fetal (baby) anomalies.
Memphis, TennesseeAges 1 minute–50 years - NCT05675722RecruitingPhase 1
Vaginal reconstruction implant test for women born without a vagina
This Phase 1 study tests a vaginal implant/reconstruction device for people born with a missing or closed-off vagina. The goal is to check safety and how well the implanted vaginal tissue construct works over follow-up visits.
Winston-Salem, North CarolinaAges 15–45 - NCT07084103Recruiting
Support program for women continuing pregnancy after a possible fetal concern
This study tests a program that offers emotional and practical support for women who choose to continue their pregnancy after learning their baby may have a health problem. It aims to see if this support helps women feel better during their pregnancy.
Sakarya, Türkiye/SakaryaAges 18 years+ - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT06573723Recruiting
Rare disease registry at Hospital Italiano
This study collects information from patients with certain rare diseases to better understand them. If you have one of these conditions and receive care at Hospital Italiano de Buenos Aires, you may be able to join.
Buenos Aires, Buenos AiresAges Any age - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT03001180Recruiting
Study blood and tissue markers in vascular anomalies
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
Boston, MassachusettsAges 1 day+ - NCT05954403Recruiting
Eye birth defect study from newborns to adults
This is a national study that follows people with certain rare eye birth defects and their families, including pregnant people. It aims to better understand how often related health issues happen and to study inheritance (DNA) in families.
Paris, Île-de-France RegionAges Any age
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Common questions
- Are there clinical trials for congenital anomalies?
- Yes. Clin2 currently lists 25 recruiting congenital anomalies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital anomalies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital anomalies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.