Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 732 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT06434935Enrolling by invitationEarly Phase 1
Trial of a new bypass graft for heart surgery
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
AsunciónAges 45–75 - NCT06086496Enrolling by invitation
Study of a new drug-releasing stent for heart arteries
This trial tests a new type of stent (a small mesh tube) that slowly releases a medicine called sirolimus to keep your heart artery open after angioplasty. It is designed for people with narrowing in their heart arteries who need a stent.
Seoul, SeoulAges 19 years+ - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06025305Enrolling by invitation
Using AI to find dangerous heart plaque on CT scans
This study uses artificial intelligence to look at CT scans of the heart to find which fatty deposits (plaque) in the arteries might be dangerous. It may help doctors better predict heart attacks.
Nanjing, JiangsuAges 18 years+ - NCT05913999Enrolling by invitation
PET and heart scans during early chemotherapy
This trial studies how a specialized heart imaging test (PET/MPI) changes during the start of chemotherapy for cancer patients. It may help researchers understand whether this monitoring approach detects heart strain early and keeps patients safer during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT05722145Enrolling by invitation
Study to assess heart artery blockage risk from CT scans
This study looks at how likely people are to have coronary artery disease (heart artery blockage) based on results from CT scans. It may help doctors better estimate risk and decide what follow-up care you may need.
Singapore, SingaporeAges 21–99 - NCT05267990Enrolling by invitation
CT calcium scan to prevent heart problems in diabetes
This trial studies whether using a heart CT “calcium score” to guide prevention can lower the chance of major heart disease in people with type 2 diabetes who have other heart risk factors. It may help by targeting prevention more personally, based on your calcium score.
YilanAges 40 years+ - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+ - NCT03674255Enrolling by invitation
Tests how accurate heart ultrasound is during stress
This study checks how well a heart ultrasound (echocardiography) works when your heart is at rest and under stress. You may benefit by getting closer attention to how the test is done, especially if it’s being used to look for blocked-heart-blood-flow problems.
Ages 18 years+ - NCT07223593RecruitingPhase 3
Orforglipron for peripheral artery disease with leg pain
This trial tests a new oral medication called orforglipron to see if it can improve walking distance in people with peripheral artery disease (PAD) who have leg pain when walking. It may be a good option if you have PAD and your walking is limited by leg cramping, not other health issues.
Birmingham, AlabamaAges 18 years+ - NCT07318610RecruitingPhase 3
Study of a new blood thinner in people with leg artery disease
This trial tests if a new blood-thinning drug (factor XI inhibitor) can prevent serious heart and leg problems in people who recently had a leg artery procedure. It compares the new drug to standard care for up to 3 years.
Alexander City, AlabamaAges 18 years+ - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT03781492Recruiting
Treatment study for stable angina symptoms
This study looks at managing and treating stable angina, a type of chest discomfort that happens predictably with activity or stress. It may help find better ways to control symptoms and improve daily life, but you must not have certain recent heart events to join.
Zabrze, Silesian VoivodeshipAges 18 years+ - NCT05865600Recruiting
PET/CT guided planning for treatment in chronic coronary disease
This trial uses a heart scan (PET/CT) to better estimate blood flow in people with long-term coronary artery disease. It aims to help doctors choose the best treatment strategy and decide who may need more invasive testing or procedures.
Herning, Central JutlandAges 18 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06631755Recruiting
How calcium affects stent healing: an imaging study
This study looks at how calcium buildup in artery walls affects how well a stent heals. Doctors will use special imaging (OCT) right after stent placement and again a month later to check the healing of the tiny metal struts.
BarcelonaAges 18 years+ - NCT07063147Recruiting
Heart ultrasound for stable chest pain management
This study uses a heart ultrasound (TTE) to help doctors better manage stable chest pain. If you have chest pain that may be from a blocked artery but haven't had a heart attack or heart procedures before, this trial could help improve your care.
TianjinAges 18 years+ - NCT07169045Recruiting
Stepper test for people with peripheral artery disease
This study checks if a 6-minute stepper test is a good way to measure walking ability in people with peripheral artery disease. You will step up and down for 6 minutes to see how far you can go.
Ankara, ÇankayaAges 18–80 - NCT07349875RecruitingPhase 4
Colchicine for non-severe coronary plaque: a trial
This trial tests if the anti-inflammatory drug colchicine can help people with non-severe coronary artery plaque seen on a CT scan. It may be an option if you have stable chest pain or related symptoms and your heart arteries are partly blocked but not severely.
NanjingAges 18 years+ - NCT07497360Recruiting
Telehealth vs. in-person sit-stand test for PAD patients
This study compares doing a 30-second sit-stand test at home via video call versus in a clinic. The goal is to see if remote testing works as well as in-person for people with peripheral artery disease (PAD). This could help you avoid extra trips to the clinic.
Izmir, BalçovaAges 18–65 - NCT07565805Recruiting
Heart Imaging Registry Comparing Two Scanning Methods
This study compares two different ways of taking detailed pictures of your heart arteries: a CT scan and an optical scan done during a heart catheterization. The researchers want to understand how well these two methods show blockages in your arteries.
BernAges Any age
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 732 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.