Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04864171Recruiting
Registry to study heart vessel imaging with a special light test
This registry collects images of coronary artery blockages during a routine heart procedure. It uses a special light-based imaging scan to help researchers understand how well the test shows artery lesions.
MiyazakiAges 20–95 - NCT04889105Recruiting
Exercise coaching for leg artery disease using a phone app
This study tests whether a phone-based program can help improve walking in Veterans with peripheral artery disease (PAD) by guiding regular exercise. It aims to reduce leg symptoms by making walking practice safer and easier to stick with.
Decatur, GeorgiaAges 40 years+ - NCT04906356Recruiting
Study of SCAD after a heart attack or unstable chest pain
This study looks at people admitted with a recent heart event (STEMI, NSTEMI, or unstable angina) and who were found to have SCAD on a heart scan. It may help doctors better understand and manage SCAD after these urgent events.
Vancouver, British ColumbiaAges 18 years+ - NCT05455515Recruiting
Shockwave IVL study for calcified heart artery blockages
This registry studies how a device called Shockwave IVL (intravascular lithotripsy) is used to treat hard, calcified blockages in heart arteries when a stent is needed. It mainly helps doctors track outcomes and safety over follow-up.
FlorenceAges 18 years+ - NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries
This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.
Chicago, IllinoisAges 50 years+ - NCT05853419Recruiting
Robotic procedure for opening blocked heart arteries
This study tests a robotic system to help doctors perform a procedure (PCI/angioplasty) to open blocked heart arteries. You may be eligible if you need this procedure and your anatomy is suitable, and if you can give informed consent.
AntwerpAges 18–120 - NCT05884840Recruiting
Cardiovascular risk screening for people without heart disease
This trial tests a new way to check cardiovascular (heart and blood vessel) risk during a routine primary care visit. If your risk score is high enough, it may help your care team better target prevention early.
BarcelonaAges 50–74 - NCT05891145Recruiting
Remimazolam to prevent irregular heartbeat after heart surgery
This trial tests whether a medication called remimazolam can help prevent atrial fibrillation—a common, irregular heart rhythm that can happen after surgery. It focuses on people having a specific planned type of heart bypass surgery and checks if the study medication reduces postoperative rhythm problems.
Yangzhou, JiangsuAges 50–70 - NCT06001502Recruiting
Virtual reality for pain and anxiety after heart bypass surgery
This trial tests whether using virtual reality (VR) goggles after heart bypass surgery can help reduce pain and anxiety. If you are having a planned CABG and have no major vision, hearing, or other health issues, you may be eligible.
Amsterdam, North HollandAges 18 years+ - NCT06273293Recruiting
Post-stent blood flow test with nitroglycerin for multivessel patients
This study tests a new way to measure blood flow after placing a stent, using a very thin wire with a camera. It helps doctors decide if the stent is working well without needing extra medication like adenosine—just a tiny dose of nitroglycerin. You may qualify if you have blockages in two or more heart arteries and are already scheduled for a stent procedure.
AlicanteAges 18 years+ - NCT06977230Recruiting
Arm-cuff protection before heart bypass in diabetes
This study tests whether a simple arm-cuff procedure done before heart bypass surgery can help protect the heart in people with type 2 diabetes. The goal is to see if this technique reduces complications during and after the operation.
MuğlaAges 45–85 - NCT07013591RecruitingPhase 2
NMN supplement before heart bypass surgery
This trial tests whether a supplement called nicotinamide mononucleotide (NMN) can help people recover better after heart bypass surgery. NMN is related to vitamin B3 and may protect the kidneys and heart during surgery.
Boston, MassachusettsAges 18 years+ - NCT07157475Recruiting
Blood vessel complications after leg artery procedures with SGLT2 inhibitors
This study looks at how a type of medicine called SGLT2 inhibitors (used for diabetes, kidney disease, or heart issues) affects blood vessel complications in people who have had a leg procedure to improve blood flow. It compares patients taking the medicine to those who are not.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07460960RecruitingPhase 2
Statin therapy for heart health and erectile function in men
This study tests whether statins, a common cholesterol-lowering medication, can improve erectile function and hormone levels in men at high risk for heart problems. It aims to see if these benefits exist beyond just lowering cholesterol.
MoscowAges 40–65 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT06788275Recruiting
Can exercise improve blood vessel health after a heart attack?
This study looks at whether aerobic exercise can improve blood vessel health in people who have had a heart attack or chest pain (angina). If you qualify, you'll join a monitored exercise program.
Alicante, AlicanteAges 45–75 - NCT07149688Recruiting
Heart disease health program for older adults in Qujiang
This study follows older adults in Qujiang District who have chronic heart or blood vessel conditions. It aims to improve care through village-based management and help researchers better understand how to support long-term heart health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT05714293Enrolling by invitation
CT measurements after surgical aortic valve replacement
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
RomaAges 18–80 - NCT07587099Recruiting
Single vs. Dual Blood Thinners After Balloon Heart Treatment
This study compares whether patients who receive a special drug-coated balloon to open a blocked heart artery (without a stent) need to take one or two blood-thinning medications afterward. The goal is to find the safest and most effective approach for preventing future blockages.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04433052Recruiting
Personalized heart-protection program for people at high risk
This trial tests whether a tailored prevention plan can improve outcomes and help with costs for people at high risk of coronary heart disease. You may join if you’ve had recent heart events or scans show significant blockage, and if you can follow the visit and app requirements.
HelsinkiAges 30–80 - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT05918380Recruiting
Study to reduce heart risk in Black adults in Cleveland
This study looks at ways to lower heart disease risk in Black or African American adults who have certain health screening risk factors. It may help you and your community by testing an approach to improve heart health and prevention.
Cleveland, OhioAges 40–75
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.