Clinical trials
Coronary Disease clinical trials
Below are recruiting coronary disease clinical trials, each written for real people, not researchers. We’re tracking 684 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06104033Recruiting
Drug-coated balloon for patients with heart artery disease in multiple vessels
This trial tests whether a drug-coated balloon is a good treatment option for people who have blockages in two or more heart arteries. It aims to see if this approach can safely open blocked arteries without a permanent stent.
SeoulAges 19–100 - NCT06185530Recruiting
Comparing stress echo vs CT scan for chest pain
This trial compares two heart imaging tests (stress echo with ultrasound of the neck, and a CT scan) to see which one better helps guide treatment for people with chest pain that might be from heart disease. If you have chest pain that is typical for heart disease, you may be able to join.
Harrow, MiddxAges 18 years+ - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06250790Recruiting
Heart Artery Check for Leg Artery Disease Patients
This trial uses a special CT scan (coronary CTA with HeartFlow analysis) to look for hidden blockages in the heart arteries of people who recently had a leg artery procedure. It may help detect heart problems early so they can be treated.
RigaAges 50 years+ - NCT06259019Recruiting
Blood test during heart procedure to find disease markers
This trial uses a special device to take a small blood sample from your heart arteries during a planned procedure. It aims to find unique markers that could help doctors better understand and treat coronary artery disease.
BournemouthAges 18 years+ - NCT06327984Recruiting
Sex hormones and inflammation in heart disease
This study looks at how sex hormones and inflammation affect chest pain and heart disease. It aims to improve care for people with coronary artery disease.
LondonAges 16 years+ - NCT06464042Recruiting
Air Quality and Early Heart Disease Study
This trial studies how air quality affects early heart disease in young adults aged 18 to 40. It looks at people in Galicia, Spain, who already have coronary artery disease and compares them to healthy individuals.
Vigo, PontevedraAges 18–40 - NCT06484647Recruiting
Stenting methods for blocked artery forks
This trial compares two techniques for placing stents in the tricky area where a coronary artery splits into two branches (a bifurcation). The goal is to see which method leads to better blood flow and fewer complications for people with blockages there.
Rivoli, TurinAges 18 years+ - NCT06535568Recruiting
Comparing one vs two blood thinners after heart artery balloon treatment
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
Milan, MIAges Any age - NCT06542393RecruitingPhase 2
Blood management for anemic patients having bypass surgery
This trial tests a blood management strategy to help people with anemia who are having coronary artery bypass surgery (CABG). If you qualify, you may receive a treatment to improve your blood counts before surgery, which could reduce the need for transfusions.
São Paulo, São PauloAges 18–80 - NCT06567938Recruiting
Heart artery procedure study for people with kidney disease
This trial uses a special ultrasound camera inside the heart's arteries to guide stent placement for people with chronic kidney disease. The goal is to see if this approach improves outcomes compared to standard methods.
Xi'an, ShaanxiAges 18 years+ - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT06700720RecruitingPhase 2
YN001-004 for coronary artery disease
This trial tests a new medicine (YN001) in people with coronary atherosclerosis (plaque buildup in heart arteries). It aims to see if the drug can help improve artery narrowing and heart health.
Canberra, Australian Capital TerritoryAges 18–75 - NCT06701968Recruiting
Healthy Nordic diet for heart artery health after heart attack
This study tests whether a healthy Nordic diet (like whole grains, berries, fish, and vegetables) can slow down hardening of the arteries in people who have had a heart attack or have stable chest pain. It lasts 18 months and aims to improve heart health.
UppsalaAges 50–80 - NCT06710210Recruiting
Hybrid scaffold-balloon vs standard stent for long blockages
This trial tests a new way to treat long, narrow blockages in heart arteries. Instead of using a standard permanent metal stent, doctors will combine a temporary scaffold with a special balloon that releases medication. The goal is to see if this approach works as well as or better than the usual metal stent.
Geneva, Canton of GenevaAges 18 years+ - NCT06831409Recruiting
Heart scan study for retired NFL players
This trial uses heart CT scans to measure plaque and blood flow in retired NFL players, helping understand heart risks.
Greenwood Village, ColoradoAges Any age - NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT06949150Recruiting
Combined heart CT scan study for coronary artery disease
This study tests a new way to use CT scans to look at both the structure of your heart arteries and how well blood flows through them. It may help doctors get a more complete picture of coronary artery disease without extra procedures.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for coronary disease?
- Yes. Clin2 currently lists 684 recruiting coronary disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.