Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 475 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06275386Recruiting
Drug-coated balloon for chronic heart artery blockages
This trial tests whether a special balloon coated with medicine (drug-coated balloon) can safely open a completely blocked heart artery, instead of using a permanent stent. It may be an option for people who have chronic chest pain or shortness of breath due to a long-standing blockage.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06545448Recruiting
Study of planned angioplasty in stable heart disease
This study looks at whether planned angioplasties (a procedure to open blocked heart arteries) are done appropriately for people with long-term stable heart disease. It aims to help doctors make better decisions for patients like you.
São Paulo, São PauloAges 18 years+ - NCT07277686Recruiting
AI face scan for hidden heart disease in high-risk people
This trial tests whether an AI system can detect signs of coronary artery disease (blockages in heart arteries) by analyzing a photo of your face. It may help identify people in the community who need further heart testing.
Zhoukou, HenanAges 18 years+ - NCT06900270Recruiting
Comparing blood markers in coronary artery disease
This study looks at blood proteins and other molecules in people with different types of coronary artery disease. The goal is to see how these markers differ between those with blocked arteries, those with narrowed arteries, and those with no artery disease. This may help doctors better understand the disease and improve treatment.
São Paulo, São PauloAges 50–80 - NCT06978439RecruitingPhase 4
Blood thinner dosing for children with Kawasaki aneurysm
This study tests the best dose of a blood thinner called rivaroxaban for children with a giant coronary artery aneurysm after Kawasaki disease. The goal is to prevent dangerous blood clots.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07612774RecruitingPhase 4
Early cholesterol-lowering drug after heart attack study
This study tests whether starting evolocumab (a cholesterol-lowering injection) soon after a heart attack helps prevent future heart problems. You'll receive the study drug or placebo for 52 weeks while your heart is monitored with imaging scans.
Chengdu, SichuanAges 40–75 - NCT07296744Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a new device called the Supira system to support the heart during a high-risk procedure to open blocked arteries. It is for people who are stable enough to wait for the procedure (not in emergency or shock).
Loma Linda, CaliforniaAges 18–90 - NCT06409585Recruiting
Heart muscle disease imaging study for scarring
This study uses advanced imaging (PET/MR or PET/CT) to look at scarring (fibrosis) in the heart muscle. It is for people with various heart muscle diseases, including heart failure with preserved pumping, thickened heart muscle, high blood pressure-related heart damage, heart inflammation, and others.
Edinburgh, ScotlandAges 30–90 - NCT06601153Recruiting
Heart health study using CT scans and blood samples
This study looks at blood samples and CT scans from people with stable coronary artery disease to find new ways to predict and prevent future heart problems. If you've had or are about to have a cardiac CT and have blood stored, you might be able to join.
Pisa, ItalyAges 40–75 - NCT06137521Recruiting
Heart artery blockage study
This study looks at people with a long-standing complete blockage in a heart artery. The goal is to understand risk factors and outcomes, which may help guide future treatments.
ShanghaiAges 18 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05714293Enrolling by invitation
CT measurements after surgical aortic valve replacement
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
RomaAges 18–80 - NCT07394959Recruiting
Guided hydration to protect kidneys in elderly heart patients
This trial tests a new way to manage fluids during heart procedures to prevent kidney injury. It uses a special vest that measures lung fluid to guide how much hydration you get.
Beijing, Beijing MunicipalityAges 60 years+ - NCT05100940Recruiting
Study after a heart procedure complication
This trial looks at what happens after complications during or after a heart procedure called coronary angiography or PCI. It may help improve care and outcomes for people who experience a problem during treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT05427084RecruitingPhase 2/Phase 3
Canagliflozin to reduce inflammation in heart artery disease
This trial tests canagliflozin to see if it lowers “vascular inflammation” in people with diabetes and stable coronary artery disease. It may help reduce harmful inflammation signals that can raise future heart risk.
Ottawa, OntarioAges 18 years+ - NCT06179212Recruiting
Comparing exercise tests for men and women with heart disease
This study compares two different exercise test methods to see which works better for men and women with heart disease. The goal is to find a test that can help doctors design better exercise programs for you.
Ottawa, OntarioAges 18 years+ - NCT05672706Recruiting
Pressure wave test for people with angina
This study looks at how a pressure waveform in the heart’s blood vessels can be analyzed to learn more about angina (chest discomfort from reduced blood flow). You may be asked to undergo specific heart/blood-flow measurements, which could help improve understanding and future care.
HsinchuAges 21 years+ - NCT06959524Recruiting
AGENT balloon for new heart artery blockages
This trial tests a drug-coated balloon (AGENT DCB) versus standard angioplasty/stenting for new blockages in heart arteries. It aims to see if the coated balloon works better and is safe for people who haven't had prior stents in that spot.
La Jolla, CaliforniaAges 18 years+ - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT06374498Enrolling by invitation
Looking inside heart arteries to improve stent placement
This study tests a new imaging technique to help doctors see inside your heart arteries during a stent procedure. It may help guide treatment and improve outcomes for people with heart disease.
Boston, MassachusettsAges 18 years+ - NCT05913908Recruiting
Valve procedure study for severe tricuspid leakage
This trial tests how well a new catheter-based valve system works for people with severe (or worse) tricuspid valve leaking who still have symptoms despite medicines. It aims to improve outcomes by treating the leaking valve without open-heart surgery, if your heart structure and overall health fit the study.
Phoenix, ArizonaAges 18 years+ - NCT06844942Recruiting
Improving heart artery imaging for chest pain diagnosis
This trial uses a special camera called OCT to take detailed pictures of the heart's arteries. It aims to see if these pictures help doctors better understand blockages and decide on treatment for stable chest pain.
Warsaw, Mazowieckie VoivodenshipAges 18 years+ - NCT04814212Recruiting
Testing a drug-coated balloon for people with bleeding risk
This trial looks at whether a “drug-coated balloon” used during a heart procedure (PCI) is safer or better for people who are at higher risk of bleeding while on blood thinners. It may help reduce complications around the time of the procedure in people like you.
Jyväskylä, Central FinlandAges 18 years+
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 475 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.