Clinical trials
Coronary Microvascular Dysfunction clinical trials
Below are recruiting coronary microvascular dysfunction clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05634031Recruiting
Study of heart vessel dysfunction seen on heart imaging
This study looks at coronary microvascular dysfunction (small blood vessel problems in the heart) using heart imaging. It may help researchers understand causes of chest tightness with activity and shortness of breath when the main heart arteries are not blocked.
New York, New YorkAges 18 years+ - NCT05426408Recruiting
Test study for heart attacks without blocked arteries
This study looks at people who may have MINOCA (heart attack symptoms with no major artery blockage) or takotsubo syndrome (a temporary stress-related heart condition). The goal is to better understand these causes and how they should be diagnosed and treated.
StockholmAges 35–79 - NCT07293338Recruiting
Heart muscle blood flow study for dilated cardiomyopathy
This study looks at how small blood vessels in the heart affect outcomes in people with dilated cardiomyopathy (an enlarged, weak heart). You may qualify if you have heart failure with a weak pump and no significant blockages in your main heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT06843902RecruitingPhase 2
Improving heart blood flow in women with HIV and diabetes or kidney problems
This trial tests a new approach to improve blood flow in the hearts of women with HIV who also have diabetes or kidney problems. It might help prevent heart disease in this population.
Boston, MassachusettsAges 45–75 - NCT07453381Recruiting
New catheter to check small heart vessels in people with chest pain
This trial tests a special wireless pressure catheter to see how well the tiny blood vessels in the heart are working. It may help people who have chest pain but don't have major blockages in their main heart arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04822649Recruiting
Assessing exercise capacity in people with heart microvascular problems
This study looks at how well you can exercise and how your body composition relates to tiny blood-vessel problems in the heart. It may help doctors better understand symptoms and function in people who don’t have major blockages in the large heart arteries.
SeoulAges 20–80 - NCT06243653Recruiting
Heart microvessel function test for heart failure recovery
This trial looks at how tiny blood vessels in the heart affect improvement in heart pumping strength for people with heart failure. It tests whether a special procedure during heart catheterization can predict recovery.
SeoulAges 19 years+ - NCT07380919RecruitingPhase 2/Phase 3
Study of ranolazine to prevent heart muscle damage after a heart attack
This trial tests whether a medication called ranolazine can help prevent damage to tiny blood vessels in the heart after a certain type of heart attack (STEMI). You may be eligible if you recently had this kind of heart attack and had a successful procedure to open a blocked artery, but still have other blockages that can be treated with stents.
Catanzaro, ItalyAges 18–80 - NCT07093528Recruiting
CS Reducer study for heart failure with preserved pumping function
This trial is testing a device called CS Reducer to see if it can help people with a certain type of heart failure (HFpEF) and a problem with small blood vessels in the heart (CMD). The device may improve blood flow and reduce symptoms.
Rochester, MinnesotaAges 18 years+ - NCT06239974Recruiting
Vericiguat for chest pain from small vessel heart disease
This study tests whether a medication called vericiguat can improve chest pain caused by problems in the tiny blood vessels of the heart (not by large blockages). You may be a candidate if you have stable chest pain, are 40–75, and have had tests showing your heart's small vessels aren't working well.
Hong KongAges 40–75 - NCT05915260Enrolling by invitation
Heart MRI study in adults with type 2 diabetes
This study uses a heart scan (MRI) to learn more about how the heart is affected in people with type 2 diabetes. It may help researchers better understand changes in the heart over time and who might benefit from future care.
SlagelseAges 18–80 - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT06669962Recruiting
Studying heart function in Takotsubo syndrome
This trial aims to understand the chemical and physical changes in the heart's blood vessels during Takotsubo syndrome, a temporary heart condition often triggered by stress. It may help doctors better diagnose and treat this condition.
Turin, TurinAges 18–90 - NCT07498231Recruiting
Small heart vessel study for chest pain
This study looks at the tiny blood vessels in your heart (the microcirculation) that can cause chest pain even when the main arteries are open. It aims to better understand and treat this type of chest pain, called chronic coronary syndrome.
BialystokAges 18–75 - NCT05198791RecruitingPhase 2
Eplerenone for heart injury without blocked heart arteries
This Phase 2 study tests whether eplerenone can improve outcomes after a heart attack (or similar heart injury) when coronary angiography shows no blocked heart arteries. It focuses on people with added cardiovascular risk factors and evaluates how well the treatment works for heart recovery and strain on the heart.
East Kilbride, LanarkshireAges 18 years+ - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+ - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT05478707RecruitingPhase 2
Treating small blood vessel problems in type 1 diabetes
This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.
Orlando, FloridaAges 18–40 - NCT07604467Recruiting
Understanding Stem Cells in Takotsubo Heart Syndrome
This study examines how certain stem cells (CD34+ cells) may contribute to takotsubo syndrome, a temporary heart condition often triggered by stress. By understanding this connection, researchers hope to improve treatment and recovery for patients with this condition.
Ljubljana, LjubljanaAges 18 years+ - NCT07055152Recruiting
Eye scan to understand heart attack risk in MINOCA patients
This study uses a special eye scan (OCTA) to look at tiny blood vessels in the eye and see if they can help predict outcomes for people who had a heart attack without blocked arteries (MINOCA). It compares these patients to others with typical heart attacks and healthy people.
Pisa, PisaAges Any age - NCT06782139RecruitingPhase 4
Enavogliflozin for heart health in obesity and diabetes
This trial tests if Enavogliflozin, a medication for diabetes, can improve blood flow in the small vessels of the heart and overall heart function in people with obesity or diabetes. You may join if you have obesity or diabetes and have had a recent heart test.
SeoulAges 20–79 - NCT05593549RecruitingEarly Phase 1
Studying blood vessel damage in type 2 diabetes
This early study looks at how “autophagy” (your body’s cell recycling process) relates to small blood-vessel problems in people with type 2 diabetes. It may help researchers understand mechanisms and possible future treatments, mainly for people who meet specific health and medication criteria.
Milwaukee, WisconsinAges 18–80
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Common questions
- Are there clinical trials for coronary microvascular dysfunction?
- Yes. Clin2 currently lists 47 recruiting coronary microvascular dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary microvascular dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary microvascular dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.