Clinical trials
Respiratory Distress clinical trials
Below are recruiting respiratory distress clinical trials, each written for real people, not researchers. We’re tracking 215 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07350018RecruitingPhase 4
Comparing Two Surfactants for Premature Babies With Breathing Problems
This trial compares two types of surfactant (Calfactant and Poractant Alfa) given through a less invasive method to very premature babies with breathing problems. It aims to see if one works better at helping them breathe without needing a breathing tube.
BursaAges birth–6 hours - NCT07344714Recruiting
Predicting breathing help needs for newborns in NICUs
This study looks at newborns in a lower-level NICU to see which ones will need extra breathing support. The goal is to better predict which babies can be kept at their current hospital instead of being moved.
Rochester, MinnesotaAges 7 months–9 months - NCT07162285Enrolling by invitation
Bubble CPAP for Preterm Babies with Breathing Problems
This trial tests a special breathing support called bubble CPAP, given right after birth in the delivery room, to help preterm babies (born before 34 weeks) who are having trouble breathing. It aims to see if starting this treatment early can improve their breathing and health.
DhakaAges 5 minutes–30 minutes - NCT06774534Recruiting
SerpinB3 protein in acute respiratory distress
This study looks at a protein called SerpinB3 and its role in severe lung inflammation (ARDS). It may help doctors understand how ARDS develops and find new ways to treat it.
Padova, PDAges 18 years+ - NCT06701656RecruitingPhase 2
Testing bevacizumab for breathing problems from ARDS
This trial tests if bevacizumab can help people with ARDS (a serious lung condition) breathe better. It is for patients with mild, moderate, or severe ARDS who are already in the hospital.
Birmingham, AlabamaAges 18 years+ - NCT06703073RecruitingPhase 2
Testing new treatments for acute respiratory distress syndrome (ARDS)
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
Birmingham, AlabamaAges 18 years+ - NCT06701669RecruitingPhase 2
Study of Paridiprubart for moderate to severe ARDS
This trial tests a new medicine called paridiprubart to see if it can help people with moderate or severe acute respiratory distress syndrome (ARDS), a serious lung condition. It may be an option if you have low oxygen levels and no known allergy to the drug.
Birmingham, AlabamaAges 18 years+ - NCT06701682RecruitingPhase 2
Study of vilobelimab for moderate to severe ARDS
This trial tests a drug called vilobelimab for people with moderate or severe ARDS (a serious lung condition). It aims to find if this treatment can help improve breathing and outcomes.
Birmingham, AlabamaAges 18 years+ - NCT06694311Recruiting
Testing CPAP and high-flow oxygen for ARDS
This study tests two types of breathing support—CPAP (a mask that pushes air into your lungs) and high-flow nasal oxygen (a special tube in your nose)—to see which works better for people with ARDS, a serious lung condition. It may help you breathe more easily without needing a breathing tube.
Barcelona, BarcelonaAges 18–80 - NCT06598709Enrolling by invitation
International study on breathing tube removal in ARDS
This study looks at how doctors safely remove breathing tubes from patients with lung injury (ARDS). It aims to find ways to improve decisions about when to take the tube out.
HiroshimaAges 16 years+ - NCT06513949RecruitingPhase 2
Testing IC14 for ARDS on a ventilator
This trial tests a new treatment called IC14 for people in the hospital on a breathing machine for ARDS (a severe lung injury). The study aims to see if IC14, which blocks a protein involved in inflammation, can help the lungs heal faster.
Seattle, WashingtonAges 18 years+ - NCT06066502RecruitingPhase 3
Precision ventilation for ARDS
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
Tucson, ArizonaAges 18 years+ - NCT06051292Recruiting
Testing balloon size for lung pressure measurement in children
This study tests how much air to put in a small balloon in the esophagus (feeding tube-like device) to measure lung pressure more accurately. It is for children on a breathing machine whose settings are stable for the next 2 hours.
AydinAges 1 month–18 years - NCT04777760Recruiting
Surfactant treatment for newborn breathing distress
This trial looks at giving a “surfactant” medicine (a substance that helps keep baby lungs open) to newborns who have serious breathing problems soon after birth. It may help babies with neonatal respiratory distress or acute breathing distress, especially if they’re treated in the early time window.
Chongqing, Chongqing MunicipalityAges 1 minute–1 day - NCT07550218Recruiting
Surfactant Delivery Methods for Premature Babies with Breathing Problems
This study looks at different ways doctors give a life-saving medication called surfactant to premature babies who are struggling to breathe. Researchers want to understand which delivery methods work best and help improve care.
GothenburgAges Any age - NCT07750288Recruiting
Studying shortness of breath in children with acute respiratory distress
This study looks at how shortness of breath (dyspnea) relates to the progression of pediatric acute respiratory distress syndrome (PARDS), a severe lung condition in children. It aims to understand breathing difficulties better to improve care.
SantiagoAges 1 month–18 years - NCT06966752Recruiting
Comparing two breathing supports for preterm babies with breathing problems
This study compares two types of breathing support (CPAP and NIPPV) for preterm babies with breathing problems. It aims to find which method works better for helping babies breathe easier.
Vilnius, Vilnius CountyAges birth–10 months - NCT06776783RecruitingPhase 3
Testing a new surfactant for breathing problems in premature babies
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
Little Rock, ArkansasAges 1 hour–1 day - NCT06658535RecruitingPhase 1
Study of NanO2 for mild breathing problems
This trial tests an experimental drug called NanO2 for people with mild respiratory distress who need a small amount of extra oxygen. The goal is to see if it can help improve oxygen levels.
Edmonton, AlbertaAges 18 years+ - NCT06188195Recruiting
Preventing newborn breathing problems with steroids
This study tests a plan to prevent a severe newborn breathing problem called NARDS. If your baby's risk is very high, you may be offered a steroid treatment that could help their lungs work better at birth.
ChongqingAges Any age - NCT05026645Enrolling by invitation
After a chemical, biological, or nuclear disaster exposure
This trial studies how patients are medically managed after being exposed to a chemical, biological, radiological, or nuclear (CBRNE) attack. It may help improve care for people who are treated after these rare disasters, using real medical information recorded by hospital staff.
College Park, MarylandAges Any age - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT07395076Recruiting
Study of immune causes of acute respiratory distress
This trial looks at how the immune system might cause severe breathing problems (ARDS). It may help doctors understand what happens in the lungs during this condition and find better ways to treat it.
ParisAges 18 years+
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Common questions
- Are there clinical trials for respiratory distress?
- Yes. Clin2 currently lists 215 recruiting respiratory distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Acute Respiratory Distress Syndrome
- Respiratory Distress Syndrome
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress Syndrome in Premature Infant
- Respiratory Distress Syndrome (Neonatal)
- Respiratory Distress Neonatal
- Respiratory Distress Syndrome, Adult
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.