Clinical trials
Cytokines clinical trials
Below are recruiting cytokines clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT01419561RecruitingPhase 2
Studying KSHV inflammatory syndrome (KICS)
This study tracks people with KICS, a condition caused by KSHV (a virus related to Kaposi sarcoma). It aims to understand the syndrome better and may lead to future treatments.
Bethesda, MarylandAges 18–120 - NCT05306080RecruitingEarly Phase 1
Rescue treatment for CAR T side effects in adults
This trial tests a rescue medicine given to treat severe immune over-reactions that can happen after CAR T cell therapy, such as cytokine release syndrome and an HLH-like syndrome. It may help calm the immune response if you are already enrolled in a specific CAR T study.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07698769Recruiting
Nirsevimab study for infants with RSV bronchiolitis
This trial looks at how well the drug nirsevimab works for babies hospitalized with RSV bronchiolitis. It also studies the body's immune response and the baby's environment. The goal is to see if nirsevimab can help infants recover from this serious lung infection.
CréteilAges birth–6 months - NCT03044509Recruiting
Testing to diagnose tuberculosis in Swiss children
This trial studies how to diagnose tuberculosis (TB) in children and teens when they are being checked after possible exposure or because TB is suspected. It may help doctors figure out faster and more accurately who has TB infection or disease.
AarauAges Up to 17 years - NCT06052618RecruitingPhase 2
Pacritinib for KSHV-associated Castleman disease and KICS
This study tests a drug called pacritinib for people with KSHV-associated multicentric Castleman disease (MCD) or KSHV-associated inflammatory cytokine syndrome (KICS). It aims to see if the drug can help control symptoms and inflammation caused by these conditions.
Bethesda, MarylandAges 18–120 - NCT06145828Recruiting
Testing a blood filter for severe pneumonia or sepsis in AIDS patients
This study tests a technique that filters harmful substances from the blood of people with AIDS who have severe pneumonia or septic shock. The goal is to see if this filter helps them recover better.
Guangzhou, GuangdongAges 18–65 - NCT06243497Recruiting
Comparing eye fluid and tear markers before and after UCP
This study compares levels of inflammatory markers (cytokines) in the fluid inside your eye and your tears before and after a procedure called UCP (ultrasound cycloplasty) to treat glaucoma. It aims to understand how the eye responds, which may lead to better treatments for high eye pressure.
Guangzhou, GuangdongAges Any age - NCT06321484RecruitingPhase 1
NK cell therapy for recurrent platinum-resistant ovarian cancer
This trial tests a new type of immune cell therapy (CIML NK cells) given directly into the abdomen for women with ovarian cancer that has come back and is now resistant to standard platinum chemotherapy. The goal is to see if these specially trained cells can fight the cancer safely.
Boston, MassachusettsAges 18–85 - NCT06447376RecruitingPhase 1
Testing siltuximab before epcoritamab to prevent cytokine release syndrome
This trial tests whether giving siltuximab before epcoritamab can help prevent or reduce cytokine release syndrome (a possible side effect where the immune system overreacts). It is for people with certain types of non-Hodgkin lymphoma that have not responded well to at least two prior treatments.
Cleveland, OhioAges 18–65 - NCT06562803Recruiting
Cleaning the blood for liver failure with sepsis
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Guangzhou, GuangdongAges 18–70 - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT02007356RecruitingPhase 2
Donor immune cell infusions for viral infections after stem cell transplant
This trial studies whether directly infusing donor-made immune cells (virus-fighting T-cells) is safe and feasible in people who still have viral infections after a stem cell transplant. It may help your body control infections from adenovirus, CMV, or EBV when standard antiviral treatments aren’t working.
BaselAges 18–65 - NCT07635056RecruitingPhase 2
Natural killer cells for hard-to-treat neuroblastoma
This trial tests specially prepared immune cells (called CIML-NK cells) from a partially matched family donor to fight neuroblastoma that has returned or stopped responding to standard treatment. The goal is to see if these cells can help patients whose cancer is difficult to control.
Cincinnati, OhioAges 1–39 - NCT07609940RecruitingPhase 4
Linvoseltamab plus tocilizumab for heavily treated multiple myeloma
This trial tests a combination of two drugs (linvoseltamab and tocilizumab) for adults with multiple myeloma that has stopped responding to standard treatments. Tocilizumab is added to help reduce serious side effects from the main drug.
Los Angeles, CaliforniaAges 18 years+ - NCT07473232Recruiting
Comparing platelet-rich plasma and cytokine-rich serum injections for knee osteoarthritis
This trial compares two types of injections (PRP and ACS) to see which one works better for knee osteoarthritis. It may help people with knee pain who have not had these injections recently.
Pamukkale, DenizliAges 40–80 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT06605378Recruiting
Antibody and cytokine study for people with CGD
This study is checking levels of antibodies and immune-signaling molecules (cytokines) in people with chronic granulomatous disease (CGD). It aims to better understand the immune system in CGD, which may help with future treatments.
Montgomery, AlabamaAges Any age - NCT07485517Recruiting
Deep vs Moderate Muscle Block for Hysterectomy
This study compares two levels of muscle relaxation (deep versus moderate) during hysterectomy surgery to see which may be better for recovery. If you are a woman scheduled for a planned hysterectomy and are in generally good health, you might be eligible.
Menoufia, Eg.mnAges 18–60 - NCT06453304RecruitingPhase 2/Phase 3
Licorice root gel for root canal infection
This trial tests a natural anti-inflammatory medicine called glycyrrhizin (from licorice root) used inside the tooth during root canal treatment. It aims to see if it helps kill bacteria and reduce infection better than standard medications.
Al MansurahAges 20–60 - NCT05054361Recruiting
Study gut immunity changes in children with type 1 diabetes
This study looks at how a type of immune cell (MAIT cells) and the gut (microbiota and gut lining) change around the time type 1 diabetes starts in children. It may help researchers understand why type 1 diabetes begins and how the gut and immune system are connected.
AntonyAges 1–15 - NCT05526950Recruiting
Check cytokine filtration for people getting double lung transplants
This study tests a method during double lung transplant surgery to remove certain immune signals (“cytokines”) that may help the transplanted lungs heal. It’s only for adults who are having a planned double lung transplant at the study sites.
Lund, Skåne CountyAges 18–80 - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50 - NCT05905328RecruitingPhase 1/Phase 2
Drug to help prevent and treat cytokine release syndrome
This Phase 1/2 trial tests CTO1681 to help prevent and treat cytokine release syndrome (CRS) in people with DLBCL who are receiving CD19 CAR T-cell therapy. CRS is a potentially serious immune reaction that can happen after CAR T treatment, and this study aims to make that complication less severe or easier to manage.
Orange, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for cytokines?
- Yes. Clin2 currently lists 81 recruiting cytokines studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cytokines trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cytokines trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.