Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06716983Recruiting
Brain activity study in dystonia with deep brain stimulation
This study looks at brain activity patterns in people with dystonia who already have a deep brain stimulation (DBS) device. By recording brain signals during MRI and other tests, researchers hope to learn how DBS helps control movement.
MilanAges 12 years+ - NCT06784388RecruitingEarly Phase 1
Deep brain stimulation for tough-to-treat depression
This early trial tests a personalized deep brain stimulation (DBS) approach for people with major depression that hasn't improved with at least two different antidepressants. DBS uses small electrodes placed in the brain to adjust mood-related circuits.
Hangzhou, ZhejiangAges 18–70 - NCT06848205Recruiting
Brain pacemaker study for freezing of gait in Parkinson's
This study looks at how a special brain pacemaker (called the Medtronic Percept device) affects walking problems like freezing of gait in people with Parkinson's. It aims to help understand and improve treatment.
Minneapolis, MinnesotaAges 21–75 - NCT06848530Recruiting
Brain activity study in movement disorders
This study looks at brain activity in people with movement disorders like Parkinson's, dystonia, tremor, and ataxia. It aims to better understand how parts of the brain work together, which could lead to better treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06912282Recruiting
Deep brain stimulation for Meige syndrome
This study tests if a new deep brain stimulation approach using one electrode on both sides of the brain can help control the muscle spasms of Meige syndrome. It is for people whose symptoms have not improved enough with standard treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06951906RecruitingPhase 4
Brain imaging study of freezing of gait after deep brain stimulation
This trial is for people with Parkinson's disease who experience freezing of gait (feeling like your feet are stuck to the floor) and are already scheduled to have deep brain stimulation surgery. The study will use MRI brain scans to understand how the surgery helps improve walking.
Charleston, South CarolinaAges 40 years+ - NCT07127913Recruiting
Closed-loop brain stimulation for hard-to-treat bipolar depression
This trial tests a closed-loop deep brain stimulation system for people with bipolar II disorder whose depression has not responded to standard treatments. The device sends targeted electrical pulses to the brain based on real-time activity, aiming to reduce depression symptoms.
San Francisco, CaliforniaAges 22–70 - NCT07228286RecruitingEarly Phase 1
Using brain stimulation to help restore consciousness
This trial tests whether electrical stimulation of a deep brain area can improve awareness in people who have been in a coma-like state for at least 3 months after a brain injury. It aims to help those who have limited or no ability to communicate or use objects.
Boston, MassachusettsAges 18–55 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT07309133Recruiting
Brain signals in dystonia
This trial records brain signals during deep brain stimulation surgery to learn more about dystonia. It may help doctors understand how to improve treatment for people with this condition.
Newcastle upon Tyne, Tyne & WearAges 18 years+ - NCT07325175Recruiting
Brain study to improve treatment for childhood dystonia
This study measures brain signals in children with dystonia to understand how the brain controls movement, with the goal of improving treatments like Deep Brain Stimulation (DBS). It also uses healthy children for comparison.
Cincinnati, OhioAges 6–21 - NCT02844049Recruiting
Quality-of-life study for treatment-resistant OCD with DBS
This study looks at whether deep brain stimulation (DBS) helps people with long-term, treatment-resistant obsessive-compulsive disorder (OCD), and how it affects quality of life. It involves careful screening because it’s meant for OCD that has not responded to several medication and therapy attempts.
CréteilAges 18–69 - NCT02686125Recruiting
Study of the Vercise brain stimulator for dystonia
This study looks at how well a specific implanted brain stimulator (the Vercise system) works for people with dystonia. It may help confirm whether the device improves symptoms and is safe for eligible patients.
GhentAges 7 years+ - NCT02537795Recruiting
Talking about OCD care after brain stimulation
This study explores what patients with OCD and their family members experience after they’ve had a surgery-based treatment called deep brain stimulation or anterior capsulotomy. Your feedback may help researchers understand what support and outcomes matter most to families and patients.
Leuven, Vlaams-BrabantAges Any age - NCT02377375Recruiting
Deep brain stimulation for OCD with more precise brain targeting
This trial studies deep brain stimulation (a surgically placed device that sends electrical signals) for people with OCD when medicines and therapy have not worked. The goal is to improve how precisely the treatment targets the brain to reduce OCD symptoms.
Leuven, Vlaams-BrabantAges 20–65 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07325487Recruiting
Brain stimulation for walking and balance in SCA6 ataxia
This study tests a new kind of deep brain stimulation that adjusts automatically to improve balance and coordination in adults with SCA6, a genetic form of ataxia. It may help patients who can still walk but have moderate to severe symptoms.
Gainesville, FloridaAges 21–89 - NCT07671261Recruiting
Brain surgery for schizophrenia guided by electrode mapping
This trial tests whether deep brain stimulation (DBS) guided by SEEG (a way to map brain activity with electrodes) can help treat schizophrenia. It is for people with moderate to severe symptoms who have not improved after trying at least two different antipsychotic medications.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07216222Enrolling by invitation
Brain response study for epilepsy or PTSD patients
This study looks at how the brain processes fear using a device already implanted to treat epilepsy or PTSD. It may help researchers understand fear responses and improve treatments.
Los Angeles, CaliforniaAges 18–70 - NCT06912841Enrolling by invitation
Deep brain stimulation for genetic movement disorders
This trial is for people of any age with a genetic movement disorder who are getting or considering deep brain stimulation (DBS). It tries to match the best DBS settings for each person.
Boston, MassachusettsAges Any age - NCT06872203Enrolling by invitation
Sensing brain signals with new DBS leads during surgery
This study tests a new way to measure brain signals during Deep Brain Stimulation (DBS) surgery for Parkinson's disease. It uses special leads that can sense brain activity, which may help doctors better adjust the stimulation in the future.
Aurora, ColoradoAges 18–75
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 208 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.