Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04828798Recruiting
Directional versus standard brain stimulation for essential tremor
This study compares two ways of delivering deep brain stimulation (DBS) to treat essential tremor that affects both arms. It may help find a DBS approach that better controls tremor while reducing side effects.
Portland, OregonAges 18–80 - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05120635Recruiting
Study brain signals tied to fear and anxiety in RNS patients
This study records electrical brain activity to understand how fear and anxiety work in people who already have an RNS (responsive neurostimulation) device placed. It may help researchers develop better ways to monitor and treat anxiety-related symptoms in the future.
Los Angeles, CaliforniaAges 18–70 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05348837Recruiting
Two-week sleep tracking for people with Parkinson’s
This study uses a wristband and a headband to track your sleep for two weeks. It’s meant to better understand sleep patterns in Parkinson’s, and may require temporarily changing your evening medication timing.
Aurora, ColoradoAges 18–80 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05600738Recruiting
Deep brain stimulation to treat epilepsy
This trial studies how adding or using deep brain stimulation devices affects people with epilepsy. It may help researchers understand which outcomes improve when these implanted devices are used.
Houston, TexasAges 18 years+ - NCT05623306Recruiting
Brain stimulation surgery for OCD using a guided DBS system
This trial studies whether deep brain stimulation surgery—guided using special scans—can reduce severe obsessive-compulsive disorder (OCD) symptoms. It may help people whose OCD has not improved enough with standard medicines and therapy.
Stanford, CaliforniaAges 22–75 - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05752656Recruiting
Tracking outcomes after deep brain stimulation for Parkinson’s
This study follows people with Parkinson’s disease to see how their thinking, behavior, and movement change over time after deep brain stimulation. It may help doctors better understand what to expect from this treatment.
RomeAges 18 years+ - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT06280092RecruitingEarly Phase 1
Stem cells plus brain stimulation for epilepsy
This trial is testing if injecting stem cells from a donor during deep brain stimulation (DBS) surgery can help control seizures better than DBS alone. It is for adults with epilepsy that does not respond to medicines.
Jacksonville, FloridaAges 18–75 - NCT06329726Recruiting
Thinking and memory after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease over time. It compares results from people who have DBS and those who receive only medication.
Milan, LombardyAges 18–70 - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06529380Recruiting
Brain stimulation for severe self-harm in children with autism
This study tests whether deep brain stimulation can reduce severe self-injurious behaviors in children with autism. If standard treatments haven't worked, this approach may offer a new option.
Toronto, OntarioAges 5–17 - NCT06561919Recruiting
Speech and language study during brain stimulation treatment
This is an extra part of the STIMPulseControl study that focuses on speech. It looks at how the brain stimulation treatment affects your ability to speak clearly and communicate.
CologneAges 18–70 - NCT06599099Recruiting
Deep brain stimulation for depression that hasn't responded to other treatments
This trial tests if deep brain stimulation (a surgical implant that sends gentle electrical pulses to a specific area of the brain) can help people with bipolar I disorder who are currently in a severe depressive episode and have not found relief from multiple treatments.
Boston, MassachusettsAges 22–64
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 208 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.