Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT06951906RecruitingPhase 4
Brain imaging study of freezing of gait after deep brain stimulation
This trial is for people with Parkinson's disease who experience freezing of gait (feeling like your feet are stuck to the floor) and are already scheduled to have deep brain stimulation surgery. The study will use MRI brain scans to understand how the surgery helps improve walking.
Charleston, South CarolinaAges 40 years+ - NCT06912841Enrolling by invitation
Deep brain stimulation for genetic movement disorders
This trial is for people of any age with a genetic movement disorder who are getting or considering deep brain stimulation (DBS). It tries to match the best DBS settings for each person.
Boston, MassachusettsAges Any age - NCT06911229Recruiting
Walking and freezing study for Parkinson's with DBS
This study looks at how the brain controls walking and freezing of gait in people with Parkinson's disease who have deep brain stimulation (DBS). It aims to help understand why freezing happens and improve treatments.
Gainesville, FloridaAges 18–80 - NCT06872203Enrolling by invitation
Sensing brain signals with new DBS leads during surgery
This study tests a new way to measure brain signals during Deep Brain Stimulation (DBS) surgery for Parkinson's disease. It uses special leads that can sense brain activity, which may help doctors better adjust the stimulation in the future.
Aurora, ColoradoAges 18–75 - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06848205Recruiting
Brain pacemaker study for freezing of gait in Parkinson's
This study looks at how a special brain pacemaker (called the Medtronic Percept device) affects walking problems like freezing of gait in people with Parkinson's. It aims to help understand and improve treatment.
Minneapolis, MinnesotaAges 21–75 - NCT06848530Recruiting
Brain activity study in movement disorders
This study looks at brain activity in people with movement disorders like Parkinson's, dystonia, tremor, and ataxia. It aims to better understand how parts of the brain work together, which could lead to better treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04085406Recruiting
Deep brain stimulation for hard-to-treat low back pain
This trial studies deep brain stimulation (DBS) to reduce severe low back pain that hasn’t improved after many standard treatments and procedures. It may help people whose pain is long-lasting and not fixable with another surgery.
Los Angeles, CaliforniaAges 40–75 - NCT06819020Enrolling by invitation
Adaptive deep brain stimulation for freezing of gait in Parkinson's
This trial tests an adaptive deep brain stimulation (DBS) system designed to improve freezing of gait in Parkinson’s disease. It is for people who still have trouble walking despite medications and are already planning to have DBS surgery.
San Francisco, CaliforniaAges 21–75 - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT06784388RecruitingEarly Phase 1
Deep brain stimulation for tough-to-treat depression
This early trial tests a personalized deep brain stimulation (DBS) approach for people with major depression that hasn't improved with at least two different antidepressants. DBS uses small electrodes placed in the brain to adjust mood-related circuits.
Hangzhou, ZhejiangAges 18–70 - NCT06716983Recruiting
Brain activity study in dystonia with deep brain stimulation
This study looks at brain activity patterns in people with dystonia who already have a deep brain stimulation (DBS) device. By recording brain signals during MRI and other tests, researchers hope to learn how DBS helps control movement.
MilanAges 12 years+ - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT06596447Recruiting
Brain activity study for severe OCD before DBS surgery
This study looks at how the brain processes approach and avoidance in people with severe OCD that hasn't improved with standard treatments. It aims to understand brain patterns that could help guide a future treatment called deep brain stimulation (DBS).
Houston, TexasAges 22–64 - NCT06599099Recruiting
Deep brain stimulation for depression that hasn't responded to other treatments
This trial tests if deep brain stimulation (a surgical implant that sends gentle electrical pulses to a specific area of the brain) can help people with bipolar I disorder who are currently in a severe depressive episode and have not found relief from multiple treatments.
Boston, MassachusettsAges 22–64 - NCT06561919Recruiting
Speech and language study during brain stimulation treatment
This is an extra part of the STIMPulseControl study that focuses on speech. It looks at how the brain stimulation treatment affects your ability to speak clearly and communicate.
CologneAges 18–70 - NCT06529380Recruiting
Brain stimulation for severe self-harm in children with autism
This study tests whether deep brain stimulation can reduce severe self-injurious behaviors in children with autism. If standard treatments haven't worked, this approach may offer a new option.
Toronto, OntarioAges 5–17 - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT04828798Recruiting
Directional versus standard brain stimulation for essential tremor
This study compares two ways of delivering deep brain stimulation (DBS) to treat essential tremor that affects both arms. It may help find a DBS approach that better controls tremor while reducing side effects.
Portland, OregonAges 18–80 - NCT06019793Enrolling by invitation
Recording brain signals during deep brain stimulation for pain
This study tests whether recording brain activity during deep brain stimulation (DBS) for chronic pain can help improve future treatments. It is for people with long-lasting, severe pain that hasn't been helped by other treatments.
Phoenix, ArizonaAges 22 years+
Hear when a new Deep Brain Stimulation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 193 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.