Clinical trials
Dementia clinical trials
Below are recruiting dementia clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06059313Recruiting
Personality study for people with memory or behavior changes
This study looks at how personality may have changed before the onset of different types of memory or behavior disorders (like frontotemporal dementia, Alzheimer's, or bipolar disorder). Researchers will talk with a family member or close friend who knew you well before the illness started.
NantesAges 18 years+ - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Chino, CaliforniaAges Any age - NCT06052397Recruiting
Sleep and body clock markers for confusion after surgery
This trial tests whether sleep patterns and body clock signals can help predict confusion after major orthopedic surgery. You would wear a watch that tracks movement to see how your sleep relates to recovery.
Boston, MassachusettsAges 70 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT06017505Enrolling by invitation
Using eSAGE for early detection of cognitive decline
This study uses a simple computer-based self-assessment (eSAGE) to detect early signs of memory or thinking problems. It may help identify cognitive impairment sooner and track changes over time.
Columbus, OhioAges 50 years+ - NCT05977712Recruiting
Circadian rhythm factors in people with memory clinic concerns
This study looks at how daily body-clock timing (circadian rhythm) and other factors may relate to memory and thinking symptoms in memory clinic patients. You may be asked to wear a small device for about 9 days to track your daily patterns.
Paris, FranceAges 18 years+ - NCT05927974Recruiting
Brain mapping during surgery for hard-to-control epilepsy
This trial studies how the brain’s control networks work during a surgery-related procedure for people with epilepsy that hasn’t improved with usual treatments. If you qualify, you may do specific tasks while the team maps and measures brain activity to better understand and guide care.
Birmingham, AlabamaAges 18 years+ - NCT05922137Recruiting
ORIENT diet for brain blood vessel narrowing
This trial studies whether a specific dietary program (the ORIENT diet) can improve brain-related thinking and memory in people with narrowed brain or neck arteries. You may be able to help test whether the diet is safe and beneficial alongside usual care, through repeated assessments over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05907343Recruiting
Brain stimulation study for memory and thinking concerns
This study tests a new brain stimulation method that may help improve memory and thinking in older adults who have memory concerns. It uses a safe, non-invasive technique called transcranial magnetic stimulation (TMS) that sends magnetic pulses to the brain.
Austin, TexasAges 18–90 - NCT05892952Recruiting
Scottish long-term study of aging and thinking
This study follows adults aged 50 and older over time to understand how thinking and memory change. You may help researchers learn what influences healthy aging and cognitive health.
Edinburgh, LothianAges 50–120 - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT05885295Recruiting
Testing thinking and memory after stroke using cognitive exams
This study looks at how thinking and memory change after a stroke using short cognitive tests. It may help researchers better understand which brain changes affect thinking, and how to measure them accurately.
LondonAges 18 years+ - NCT05882344Enrolling by invitation
Deep brain stimulation for early Alzheimer’s memory problems
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
Nashville, TennesseeAges 60–80 - NCT05879211Enrolling by invitation
Care learning lab for Duke Health patients
This trial is a “learning laboratory” that studies how best to provide goal-focused care. It may help improve care experiences for Duke Health patients, based on what the study learns.
Durham, North CarolinaAges 18 years+ - NCT05877391Recruiting
Collecting sexual and gender identity information in hospice
This study tests an approach to collect and use sexual orientation and gender identity (often called “SOGI”) information for people receiving hospice care. The goal is to help hospice teams better understand and support patients’ needs.
Aurora, ColoradoAges 18 years+ - NCT05858996RecruitingPhase 2
Testing a pain care guideline for older adults with dementia
This trial tests a clinical guideline to improve how pain is identified and managed. It may help if you or your loved one has dementia and ongoing pain, with a focus on better pain care in nursing homes.
Baltimore, MarylandAges 60 years+ - NCT05800028Recruiting
Study brain scans and social life in memory changes
This study looks at how memory and brain function relate to social interactions. It focuses on people with probable Alzheimer’s disease or a specific language-related condition, and on healthy partners matched by age and social background.
CaenAges 18–85 - NCT05794061Recruiting
Testing new ways to assess brain and behavior health
This study is developing and checking better tests to understand neurological (brain-related) and psychiatric (mental health) conditions. If you have a diagnosed brain or mental health condition—or you’re being considered as a healthy person—your results will help researchers see how well these assessments work.
Milan, LombardyAges 20–100 - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT05776641Recruiting
Light and sound training to help prevent Alzheimer’s memory loss
This study tests whether regular “gamma” light and sound stimulation can delay or prevent Alzheimer’s disease-related memory decline in people who are currently not showing dementia but are at higher risk. It uses brain testing (MRI and PET) and memory/language tests over about 13 months.
Boston, MassachusettsAges 55–90 - NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Birmingham, AlabamaAges 55–90 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65
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Common questions
- Are there clinical trials for dementia?
- Yes. Clin2 currently lists 486 recruiting dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.