Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07474363Recruiting
Depression differences between men and women
This study looks at how depression affects men and women differently, including symptoms, strength to cope (resilience), and feelings of stigma. It aims to understand these differences to improve treatment.
Eskişehir, EskişehirAges 18–65 - NCT07480525Recruiting
Escitalopram for first-time depression
This trial tests whether escitalopram, a common antidepressant, helps people who are experiencing their first episode of depression and have never taken medication for it. It also looks at how the drug works in the brain.
Beijing, Beijing MunicipalityAges 18–65 - NCT05855421Recruiting
Ear acupuncture sessions for moderate depression during COVID
This trial tests whether auricular (ear) acupuncture can safely improve symptoms of moderate depression during the COVID period. You may be able to join if you’re an adult with moderate depression and can attend the study sessions.
Palhoça, Santa CatarinaAges 18–50 - NCT07454070Recruiting
Testing ear nerve stimulation for depression after a heart attack
This trial tests if a gentle, non-invasive ear stimulation device can help relieve depression in people who have had a heart attack and a stent placed. It aims to offer a drug-free option for those who choose not to take antidepressants or see a therapist.
Xi'an, ShaanxiAges 18 years+ - NCT06807801Recruiting
Baby swimming for postpartum depression and bonding
This study looks at whether taking your baby for swimming sessions can help with feelings of depression and strengthen the bond between you and your baby after childbirth.
UppsalaAges 18 years+ - NCT07424781Recruiting
Fluoxetine and emotional experience in young adults
This study looks at whether fluoxetine, a common medication for mood, affects how young adults (18-24) experience emotions. It aims to understand emotional processing in healthy individuals without psychiatric history.
Oxford, OxfordshireAges 18–24 - NCT07398040Enrolling by invitation
Anti-inflammatory diet for anxiety and depression
This study tests whether following a personalized anti-inflammatory diet can help reduce symptoms of anxiety, depression, or stress. You would need to live in Zaragoza, speak Spanish, and already have a low-to-moderate Mediterranean diet score.
Zaragoza, ZaragozaAges 18 years+ - NCT07380451Recruiting
Personalized therapy for depression with childhood trauma
This trial tests a flexible, personalized therapy program for adults with depression who also have a history of childhood trauma and personality challenges. It aims to see if this approach helps more than standard care, and you'll receive weekly therapy from a community clinic in Chile.
SantiagoAges 18–65 - NCT07373470Recruiting
Pharmacist help with depression meds using your DNA
This trial tests whether a pharmacist can use your genetic information to better manage your depression medications. It may help find the right drug or dose for you.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07324070Recruiting
Adding TMS to ECT for hard-to-treat depression
This study tests whether adding TMS to ECT can better treat depression that hasn't improved with other treatments. It is for adults with moderate to severe major depression who haven't had these treatments recently.
Prague, CzechAges 18 years+ - NCT06740396Recruiting
Depression in heart disease patients in Baghdad
This study looks at how common depression is in people with coronary artery disease and how severe it is. If you have heart disease and are being treated at a hospital in Baghdad, you can help doctors understand the link between heart health and mental health.
BaghdadAges 18 years+ - NCT07284667RecruitingPhase 2
A new medicine for depression that hasn't improved with other treatments
This trial tests a new medicine called ACP-211 in adults with major depression who have not gotten enough relief from at least two previous antidepressants. The goal is to see if it can help when other treatments have not worked well.
Birmingham, AlabamaAges 18–65 - NCT07282678Recruiting
Adaptive brain stimulation for treatment-resistant depression.
This study tests a new brain stimulation device that adjusts its signal in real time to treat depression. It's for people who haven't gotten enough help from antidepressants and are looking for a non-drug option.
Durham, North CarolinaAges 22 years+ - NCT07266545RecruitingPhase 4
RNA markers for antidepressant response in depression
This study looks at how RNA might help predict which antidepressant works best for you. It tests two medications: vortioxetine and cariprazine, in people with major depressive disorder or bipolar depression.
Rochester, MinnesotaAges 18–65 - NCT07251491RecruitingPhase 1/Phase 2
Psilocybin for depression after spinal cord injury
This trial tests whether psilocybin (a substance found in certain mushrooms) can help treat depression in people with a spinal cord injury. You would receive the study drug in a controlled setting, and your progress would be monitored closely.
The Bronx, New YorkAges 22 years+ - NCT07258914Recruiting
Repetitive TMS for depression in adults with autism
This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can safely and effectively treat major depression in adults who also have autism spectrum disorder. rTMS uses magnetic pulses to stimulate specific brain areas without surgery.
RennesAges 18–65 - NCT07250893Recruiting
Resolving early life stress in depression: a psychotherapy study
This trial tests if a specific type of psychotherapy can help people with moderate-to-severe depression who experienced stress or adversity in childhood (before age 18). Researchers want to see how the treatment works in the brain and whether it improves depression symptoms.
Hamilton, OntarioAges 18–65 - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07246044Recruiting
Brain stimulation for teens with bipolar depression targeting S1
This trial tests a non-invasive brain stimulation technique (HD-tDCS) to see if it can help teens with bipolar disorder who are currently in a depressive episode. It aims to find a new treatment option for adolescent bipolar depression.
Nanjing, JiangsuAges 12–18 - NCT06724666Recruiting
Online therapy for teens with anxiety or depression
This study tests an online therapy program for teens aged 13–17 who feel anxious, depressed, or both. The program is designed to help you understand and manage these feelings through short, internet-based sessions, and you can do it from home.
Cluj-NapocaAges 13–17 - NCT06621394Recruiting
Mediterranean diet and mindful eating for depression and obesity
This study tests if a Mediterranean diet combined with mindful eating can help reduce depression severity in people who have both obesity and major depressive disorder. You would follow a special eating plan and learn mindfulness techniques to see if they improve your mood.
StuttgartAges 18 years+ - NCT07217223Recruiting
Home-based brain stimulation for treatment-resistant depression
This study tests whether a gentle brain stimulation technique called tDCS can help people with depression that hasn't improved with medication. It can be done at home using a special headset and an internet connection.
San Diego, CaliforniaAges 18–85 - NCT07203144RecruitingPhase 2
Selenium for depression in teens
This study tests whether taking selenium (a mineral found in some foods) can help improve depression symptoms in young people. Participants will take selenium supplements and have their mood and brain activity monitored over time.
Chongqing, Chongqing MunicipalityAges 12–18 - NCT07207239Enrolling by invitation
Brain stimulation for treatment-resistant depression
This trial is testing a type of brain stimulation therapy called theta-burst rTMS to see if it helps with depression that hasn't improved with standard treatments. It also uses brain scans to predict who might respond best.
Budapest, Pest CountyAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.