Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06725160Recruiting
Happiness coaching for moms and their young children
This trial tests a program that helps mothers with depression learn positive parenting skills to boost their child's emotional well-being. If you are a mother with high depressive symptoms and have a child between 4 and 6 years old, this study may be an option.
Pittsburgh, PennsylvaniaAges 4–99 - NCT06726304Enrolling by invitation
Increasing physical contact for mothers with anxiety or depression
This study tests whether using a baby carrier more often helps mothers with anxiety or depression feel more connected to their babies. It is for mothers who had a healthy baby and were diagnosed with anxiety or depression during pregnancy.
Montreal, QuebecAges 18 years+ - NCT06713616RecruitingPhase 3
Esketamine vs. ketamine for hard-to-treat depression
This study compares the effectiveness of esketamine (Spravato) and another similar drug, ketamine, for adults with major depression that has not improved after trying at least two other antidepressants. It aims to find out which treatment works better.
Milford, ConnecticutAges 18 years+ - NCT06700902Recruiting
Support program for college students with mental health challenges
This study tests a program called 'Taking Action' to help college students with serious mental illnesses manage their health and daily life. If you're a student with a mental health condition, you may be able to join to learn new coping skills through group education.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06689878Recruiting
Mobile therapy for anxiety and depression after stroke
This study tests if a mobile cognitive behavioral therapy app can help reduce anxiety and depression in people who have had a stroke. If you are between 40 and 79 and have ongoing feelings of worry or low mood after your stroke, this therapy might be a convenient option.
New York, New YorkAges 40–79 - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT06651554Recruiting
Suicide prevention app study for teens in Bogota
This trial tests a digital platform designed to help prevent suicide among teenagers. It aims to make mental health support more accessible for students in Bogota schools.
Bogotá, ColombiaAges 14–19 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT06652503Recruiting
Student wellness and emotional growth program
This trial tests a program called SWAG-R designed to help NSU undergraduate students build resilience and manage emotions. It may be a good fit if you are not currently in therapy or dealing with serious mental health issues.
Fort Lauderdale, FloridaAges 18 years+ - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT06633458Recruiting
Family communication in teen psychiatric care
This trial looks at how teens in a hospital psychiatry unit feel about talking with their parents and whether that affects their treatment progress.
Hamburg, Free and Hanseatic City of HamburgAges 14–17 - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06633913Recruiting
Brain imaging and stimulation study for depression
This study uses brain scans and magnetic stimulation to understand depression. It is testing how the brain responds to treatment and may help find better ways to treat depression.
Iowa City, IowaAges 18–65 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT06605105Enrolling by invitationPhase 3
Long-term extension trial of CYB003 for depression
This long-term study is for people who already completed an earlier trial of the experimental drug CYB003 for major depression and who stayed on their regular antidepressant. It looks at the safety and effects of taking CYB003 again over many months.
Phoenix, ArizonaAges 18–85 - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06606249Recruiting
Self-help coping skills for stressed university students
This trial tests a self-guided program, Self-Help Plus, to help university students manage stress and catch up with their studies. It may be helpful if you are behind on exams and feeling distressed.
Bari, BariAges 18 years+ - NCT06595251Recruiting
Fit2Play park study for better health
This trial looks at health programs in Miami-Dade parks. If you are already in the Fit2Play study, your data will be used to learn how these programs help people get healthier.
Miami, FloridaAges 6–14 - NCT06586619Recruiting
Tai chi and qigong for older adults with HIV
This study tests whether a remotely taught tai chi and qigong program can improve mood and well-being in people aged 50–75 who are living with HIV. You can join from home using a smartphone.
Miami, FloridaAges 50–75 - NCT06587230Recruiting
Tealeaf-NC: Teacher-led support for students in North Carolina
This study tests the Tealeaf program, where teachers and school staff work together to support students who may be struggling emotionally or behaviorally. It aims to help students in kindergarten through 8th grade who have elevated scores on a behavior and emotions questionnaire.
Chapel Hill, North CarolinaAges 5–99 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.