Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06569303Recruiting
Filipino family health study for parents of children 8–12
This study offers a free parenting program for Filipino families with children ages 8–12 to help strengthen family bonds and manage challenges together. It is designed to understand what works best for your community.
Pasadena, CaliforniaAges 8 years+ - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+ - NCT06576076Recruiting
Cannabis, emotions, and risk study for teens
This study explores how daily cannabis use affects emotions and risk behaviors in teenagers. You'll answer quick surveys on your phone and wear a Fitbit for up to 3 months.
Boston, MassachusettsAges 12–18 - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT06546917Recruiting
Cognitive training trial for mild depression with brain scans
This trial tests a computer-based cognitive training program (bWell-D) to see if it can improve thinking skills like memory and focus in people with mild depression. You will also have an MRI brain scan to see how the training affects your brain.
Vancouver, British ColumbiaAges 19–55 - NCT05991154Recruiting
JoyPop app study for Indigenous young adults on a wait-list
This study tests a mobile app called JoyPop designed to help improve mental health and well-being. It is for Indigenous young adults who are waiting for counseling services at Dilico Anishinabek Family Care.
Thunder Bay, OntarioAges 18–25 - NCT06526078Recruiting
Combining brain training with ketamine for depression
This study tests if adding computer-based cognitive training to ketamine treatment can improve mood in people with depression that hasn't responded to other treatments. It aims to see if the combination works better than ketamine alone.
Oakland, CaliforniaAges 18–80 - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT06512194RecruitingPhase 2
Psilocybin for depression study
This trial tests whether psilocybin can help people with major depression who are currently having a depressive episode. It aims to understand how the treatment works and if it is safe and effective.
Edwards, ColoradoAges 18–70 - NCT06488573Recruiting
Nutrition program to improve heart health in bipolar disorder
This study tests if a nutrition program can help people with bipolar disorder improve their heart health. It is for adults aged 18 to 60 with bipolar I or II who are already on medication and are at moderate or high risk for heart problems.
São Paulo, São PauloAges 18–60 - NCT06490315Enrolling by invitation
Studying OkeyMind for social anxiety in young people
This trial tests if a smartphone program called OkeyMind helps reduce social anxiety in young people aged 15-24. It also looks at whether the program is worth the cost.
Hong Kong, Hong KongAges 15–24 - NCT06494384Recruiting
Problem-solving treatment in community health centers
This trial tests if training therapists in a specific counseling method (problem-solving treatment) helps patients with depression. It's for adults who have depression and are seen at certain community health centers.
Portland, OregonAges 18 years+ - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06239545Recruiting
JoyPop app for mental health support in young adults
This trial tests a mobile app called JoyPop designed to help young adults manage their mental health while they wait for services. It aims to see if using the app can improve well-being and reduce distress.
Thunder Bay, OntarioAges 18–25 - NCT06239519Recruiting
JoyPop mobile app for youth mental health
This trial is testing a mobile app called JoyPop to help youth with their mental health while they wait for counselling. Participants use the app for a few weeks and share feedback.
Thunder Bay, OntarioAges 12–17 - NCT06455527Recruiting
Heart-guided brain stimulation for depression
This trial tests whether a non-invasive brain stimulation technique called tDCS, guided by your heart rate, can help improve depression symptoms. If you have mild to moderate depression and are not on medication, you may be eligible.
New York, New YorkAges 18–65 - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06399991Recruiting
Improving mental health care in Malawi clinics
This study is testing a new way to help clinics in Malawi better support patients with mental health needs. If you are an adult patient at a participating clinic who has recently had symptoms of depression or anxiety, you may be eligible.
ChiradzuluAges 18 years+ - NCT06408012Recruiting
Master platform for mood disorder trials
This trial creates a flexible platform to test new treatments for mood disorders like bipolar disorder and depression. It also includes healthy volunteers as a comparison group.
Calgary, AlbertaAges 16 years+ - NCT06395558Recruiting
Online support program for cardiac arrest survivors
This trial tests if an internet-based program helps people recover after a cardiac arrest. You may qualify if you were discharged from the hospital with good brain function and can use the web.
Bologna, BolognaAges 18–80
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.