Clinical trials
Depression and Anxiety Symptom clinical trials
Below are recruiting depression and anxiety symptom clinical trials, each written for real people, not researchers. We’re tracking 165 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07653022Enrolling by invitation
Turkish symptom questionnaire for Turkish speakers with language barriers
This study tests a Turkish version of a questionnaire for Turkish-speaking patients who have psychological complaints but face language barriers. It aims to help doctors better understand their symptoms.
Jette, Brussels CapitalAges 18 years+ - NCT06766526Recruiting
Online support for emotional adjustment after prostate cancer
This trial tests an online support program to help men cope with emotional distress after prostate cancer. You participate from home using a computer or smartphone.
LinköpingAges 18 years+ - NCT00018057RecruitingPhase 2
Brain study of pediatric anxiety disorders
This study looks at how the brain works in children and adults with anxiety disorders. It uses brain scans (fMRI) and other safe tests to understand anxiety better.
Bethesda, MarylandAges 8–65 - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT07280481Recruiting
Mindfulness for emotional distress
This trial tests a weekly mindfulness program to help people with anxiety or depression. It aims to see if learning mindfulness can improve your emotional health.
BeijingAges 18 years+ - NCT07115329RecruitingPhase 2
Testing Zelquistinel for major depression
This study tests a new oral medication called Zelquistinel (taken as a tablet) against a placebo for treating major depressive disorder. Researchers want to see if it can reduce depression symptoms, especially when other antidepressants haven't been tried or haven't worked.
Phoenix, ArizonaAges 18–64 - NCT05921201Recruiting
RRE program to prevent depression in Chinese American teens
This trial tests an education and skills program (Relax, Reflect, and Empower, or RRE) designed to help prevent depression in Chinese American teens. It may help by teaching coping strategies before symptoms become more serious.
Boston, MassachusettsAges 14–18 - NCT07221409Recruiting
Virtual reality to help cancer patients feel better during treatment
This trial tests whether using virtual reality can help reduce stress, anxiety, and other emotional symptoms in people being treated for cancer. Patients undergoing chemotherapy, bone marrow transplant, or CAR-T therapy may be eligible.
Jacksonville, FloridaAges 18–90 - NCT04191811Recruiting
Using brain signals to predict CBT success for mood or sleep issues
This study tests whether brain measurements can help predict who will benefit from a type of talk therapy called CBT (cognitive behavioral therapy). If you have depression, social anxiety, or insomnia, your brain “response variability” may be used to personalize or improve treatment planning.
Huddinge, Stockholm CountyAges 18 years+ - NCT06438276Recruiting
Mental health support for teens through school services
This study tests whether psychiatric outreach nurses can help teenagers aged 12-16 who are dealing with mood issues, anxiety, obsessive-compulsive or eating disorder symptoms, or mild self-harm. The goal is to see if this extra support improves their mental health compared to the usual school services.
Kuopio, Northern SavoniaAges 12–16 - NCT07719517Recruiting
Morning activities to boost mood after stroke
This study tests if doing simple, guided activities in the morning can help improve your mood after a stroke. If you often feel down and have trouble getting going in the morning, this program might offer a way to feel better.
Hong KongAges 18 years+ - NCT07698379Recruiting
Preventing burnout in healthcare workers with compassion therapy
This trial tests whether an online compassion-based therapy program can prevent burnout in Spanish doctors and nurses. It aims to help you manage stress and emotional exhaustion from work.
Zaragoza, SpainAges 18–75 - NCT06121284RecruitingPhase 2
Brain stimulation plus medication for youth suicide
This study tests if a new type of brain stimulation (iTBS) combined with a medicine called D-cycloserine can reduce suicidal thoughts in young adults who have previously attempted suicide. It aims to find a faster, mood-boosting treatment option for young people at risk.
Calgary, AlbertaAges 18–24 - NCT04276922Recruiting
Creative arts program to reduce healthcare burnout
This study tests a creative arts program to help reduce burnout symptoms in people who work in hospitals. If you’re feeling emotionally drained or disconnected at work, participating may help you build coping and well-being skills.
Aurora, ColoradoAges 18–85 - NCT07278466Recruiting
Comparing app support strategies for depression and anxiety
This study compares different ways of supporting people who use a mental health app for depression or anxiety. It aims to find which type of support helps people feel better and stick with the app.
Madison, WisconsinAges 18–65 - NCT07240792Recruiting
CBT for rural high school students with stress or mood issues
This study provides free cognitive-behavioral therapy (CBT) sessions led by college students to help rural high school students manage symptoms of depression, anxiety, or stress. It aims to see if this type of talk therapy can improve emotional well-being.
Hershey, PennsylvaniaAges 13–18 - NCT07218250Recruiting
One-time counseling for depression, anxiety, and distress in cancer
This study tests if a single counseling session can help reduce depression, anxiety, and distress in people with cancer. You may participate if you have been diagnosed with cancer and are waiting for ongoing counseling support.
Basking Ridge, New JerseyAges 18 years+ - NCT07172607Recruiting
Can Avnace eZZe improve sleep?
This study tests a dietary supplement called Avnace eZZe to see if it helps improve sleep in adults with insomnia. You may be able to join if you have a diagnosis of insomnia and are not currently using sleep aids.
TaipeiAges 18 years+ - NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07091032Recruiting
Building connections for better health
This study tests if helping people address obesity, cancer screenings, or mental health struggles can improve their overall health. You may qualify if you have obesity, are behind on colon or cervical cancer screening, or have depression or anxiety.
Boston, MassachusettsAges 18–75 - NCT07082218Recruiting
Sleep program to help teens recover from concussion
This study tests whether a sleep-focused program can help teenagers recover from a concussion. If you have ongoing symptoms after a concussion, this program might improve your sleep and speed up recovery.
Aurora, ColoradoAges 10–19 - NCT06928480Recruiting
Unified Protocol for Emotional Health in Long COVID
This study tests a program to help people with Long COVID manage emotional difficulties like depression or anxiety. It combines different therapy approaches into one treatment, which you can receive online from home.
Zaragoza, ZaragozaAges 18 years+ - NCT06978166Recruiting
Digital therapy for chronic pain and mood
This study tests a smartphone app that gives you personalized tips and exercises to help manage chronic pain along with depression or anxiety. It is designed for adults ages 45 and older and aims to see if these digital check-ins can improve how you feel day to day.
St Louis, MissouriAges 45 years+
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Common questions
- Are there clinical trials for depression and anxiety symptom?
- Yes. Clin2 currently lists 165 recruiting depression and anxiety symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and anxiety symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and anxiety symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.