Clinical trials
Depression and Anxiety Symptom clinical trials
Below are recruiting depression and anxiety symptom clinical trials, each written for real people, not researchers. We’re tracking 164 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT07458100Recruiting
Step-by-step digital therapy for emotional disorders
This trial tests a digital stepped-care program for people with emotional disorders like depression, anxiety, OCD, PTSD, or eating disorders. It uses online tools to help manage symptoms, and you may access different levels of support based on your needs.
BeijingAges 18–65 - NCT07436351Recruiting
ACT With CF Self-Help Toolkit
This trial tests an online self-help program based on acceptance and commitment therapy (ACT) for adults with cystic fibrosis who are feeling depressed or anxious. It aims to help you manage these feelings and improve your well-being.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07341425Recruiting
Focused therapy for stress, anxiety, and depression
This trial tests a short, online therapy program (Focused Acceptance and Commitment Therapy) designed to help you manage stress, anxiety, or depression. You can participate from home using a smartphone, tablet, or computer with a camera.
Aarhus CAges 18 years+ - NCT07000799Enrolling by invitation
School absence and well-being study for elementary kids
This study tests a group program to help children who struggle with school attendance due to anxiety or sadness. It aims to boost well-being and reduce school avoidance.
OsloAges 8–13 - NCT06324864Recruiting
START NOW Adapted for migrant teens, ages 14-18
This trial tests a culturally adapted version of a program called START NOW. It's designed to help teenagers who are migrants in Switzerland and are feeling depressed or very stressed learn new skills to feel better.
Basel, Canton of Basel-CityAges 14–18 - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06038721Recruiting
Unified Protocol for kids with emotional concerns
This trial tests a program called Unified Protocol for children ages 7–17 who have emotional difficulties like anxiety, depression, trauma, or obsessive-compulsive symptoms. It aims to help kids and their parents learn skills to manage these feelings together.
Coral Gables, FloridaAges 7–17 - NCT05897619Recruiting
CBT skills app for pregnancy and postpartum stress and coping
This study tests whether a new phone app that teaches “cognitive behavioral therapy” (CBT) skills is helpful and easy to use for people who are pregnant or recently gave birth. It also checks safety and whether participants feel the app is acceptable to use over time.
New York, New YorkAges 18 years+ - NCT05585164Recruiting
Therapy program for postpartum depression up to one year
This trial tests a structured talk-therapy program for postpartum depression in the first year after having a baby. It may help by reducing depressive symptoms and improving day-to-day functioning.
New York, New YorkAges Any age - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06633458Recruiting
Family communication in teen psychiatric care
This trial looks at how teens in a hospital psychiatry unit feel about talking with their parents and whether that affects their treatment progress.
Hamburg, Free and Hanseatic City of HamburgAges 14–17 - NCT07022925Recruiting
Wearable device for tracking hot flushes in perimenopause
This study will test if a wearable device can accurately track symptoms like hot flushes and night sweats in women going through perimenopause. If you are between 35 and 55 and experiencing these symptoms, your participation could help improve future symptom monitoring.
London, OntarioAges 35–55 - NCT07470645Recruiting
Probiotics for stress and anxiety in students
This study tests whether taking a probiotic supplement can help reduce stress and anxiety in students. If you are a student aged 18-40 who experiences moderate stress and mild anxiety, and you don't have certain health conditions, you may be able to join.
LublinAges 18–40 - NCT05384158Recruiting
Testing a computer game for low mood, low pleasure, or anxiety
This trial looks at how a computer-based task performs when someone is dealing with depression-like symptoms, such as low mood, low interest/pleasure, or anxiety that affects daily functioning. You might find it helpful if you fit their symptom and safety requirements and are comfortable with computer tasks and (for some parts) MRI scanning.
Roanoke, VirginiaAges 25–50 - NCT07409792Enrolling by invitation
Ear seed therapy for anxiety, sleep, and IVF success
This trial tests if sticking tiny seeds on ear points (auricular therapy) can help women going through IVF feel less anxious, sleep better, and possibly improve their chances of pregnancy. It is for women with infertility who are about to have a frozen embryo transfer and have some anxiety or sleep problems.
Hangzhou, ZhejiangAges 20–45 - NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT06789250Recruiting
Online therapy for mental health and alcohol use issues
This trial tests an internet-based cognitive behavioral therapy program designed for people who struggle with both mental health symptoms (like depression or anxiety) and problematic alcohol use. The goal is to see if this approach can help improve both issues at the same time, conveniently from home.
LinköpingAges 18 years+
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Common questions
- Are there clinical trials for depression and anxiety symptom?
- Yes. Clin2 currently lists 164 recruiting depression and anxiety symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and anxiety symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and anxiety symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.