Clinical trials · Pittsburgh, PA
Depression clinical trials in Pittsburgh
We’re tracking 19 recruiting depression studies with a site in or near Pittsburgh — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Pittsburgh
- NCT05219955Recruiting
Study of caregiver stress and sleep in older adults
This study looks at how caregiver stress affects sleep problems—especially trouble getting going in the morning. If you are a caregiver for someone with dementia and have specific morning sleep/energy difficulties, you may be able to join and help researchers better understand what helps.
Pittsburgh, PennsylvaniaAges 55 years+ - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Pittsburgh, PennsylvaniaAges 12–18 - NCT06829953Recruiting
App-based study for teens with depression
This study is testing whether a smartphone app can help teens who feel depressed and have lost interest in things. It's looking for youth aged 12–18 with moderate to severe depression who are willing to use the app.
Pittsburgh, PennsylvaniaAges 12–18 - NCT06835985Enrolling by invitation
Social media help for teens bullied online
This study tests a social media program to help teens who have been bullied online and feel depressed. It aims to see if the program can reduce their sadness and help them cope better.
Pittsburgh, PennsylvaniaAges 12–18 - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT06963463Recruiting
Sleep & light therapy for teens with depression
This study tests a program that combines sleep and light therapy to help teens with depression and sleep problems feel better. It focuses on improving your sleep schedule and adding bright light exposure to boost mood.
Pittsburgh, PennsylvaniaAges 12–18 - NCT06976840Recruiting
Rapid antidepressant effects of new brain stimulation methods
This trial tests whether two types of non-invasive brain stimulation can quickly improve depression symptoms. It may be an option for adults with major depression who are not currently taking psychiatric medication.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Pittsburgh, PennsylvaniaAges 18–50 - NCT06817993Recruiting
How social media affects the teen brain
This study looks at how social media affects the brains of teens with depression. You would complete smartphone surveys and have one brain scan (MRI) to help researchers understand these connections.
Pittsburgh, PennsylvaniaAges 13–17 - NCT07346014Recruiting
Sleep therapy for college students at risk of suicide
This study tests if improving sleep can help college students who are already getting mental health treatment for suicidal thoughts. You will try light therapy or sleep schedule changes to see if it reduces suicide risk.
Pittsburgh, PennsylvaniaAges 18–25 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Pittsburgh, PennsylvaniaAges 55 years+ - NCT06400121RecruitingPhase 2
Apimostinel plus brain training for depression
This study tests if a new drug called apimostinel, combined with computer-based brain training exercises, can improve depression symptoms. It may help people with major depression who also have negative thoughts about themselves.
Pittsburgh, PennsylvaniaAges 18–60 - NCT06725160Recruiting
Happiness coaching for moms and their young children
This trial tests a program that helps mothers with depression learn positive parenting skills to boost their child's emotional well-being. If you are a mother with high depressive symptoms and have a child between 4 and 6 years old, this study may be an option.
Pittsburgh, PennsylvaniaAges 4–99 - NCT02434393Recruiting
Studying brain changes in late-life depression and memory decline
This study looks at how thinking and memory change in people with depression later in life, using brain imaging and related assessments. Your past participation and whether your treatments are stable enough around the time of the brain scan may determine whether you can join.
Pittsburgh, PennsylvaniaAges 65 years+ - NCT05703256Recruiting
Brain training with feedback to help depression
This trial tests a type of brain training called amygdala neurofeedback to reduce depression symptoms. It may help by teaching your brain patterns to become less “stuck” in depression-related activity.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Pittsburgh, PennsylvaniaAges 18–100 - NCT05712772Recruiting
Study how light affects mood in depressed teens and young adults
This study looks at how different light patterns may change brain and mood responses in people with depressive symptoms. It may help researchers understand why light can affect mood and guide future treatments.
Pittsburgh, PennsylvaniaAges 12–30 - NCT06034821Enrolling by invitationPhase 4
ECT vs. ketamine for suicidal depression in adults
This trial compares two treatments—ECT (electroconvulsive therapy, which uses electrical stimulation) and ketamine (a medicine given as a shot)—to see which works better for quickly reducing suicidal depression. It is for adults who are in a severe depressive episode with active suicidal thoughts.
Pittsburgh, PennsylvaniaAges 18–90 - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
Pittsburgh, PennsylvaniaAges 3–17
Hear when a new Depression trial opens near Pittsburgh, PA
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Depression trials in other cities
Where these studies are running near Pittsburgh
Institutions with a site for the recruiting depression studies listed above.
- University of Pittsburgh · 8 studies
- Western Psychiatric Hospital · 4 studies
- UPMC Shadyside Hospital · 2 studies
- Bellefield Towers
- Children's Community Pediatrics
- Kids Plus Pediatrics
- Magee-Womens Hospital of UPMC
- Redeemer Health - Holy Redeemer Hospital
What taking part in a depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting depression studies in Pennsylvania.
Common questions
- Are there depression clinical trials near Pittsburgh?
- Yes. We're currently tracking 19 recruiting depression studies with a site near Pittsburgh, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depression study near Pittsburgh?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pittsburgh to take part?
- Not necessarily. These studies have a site near Pittsburgh, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depression studies open near Pittsburgh regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.