Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,504 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06502717Recruiting
Personalized nutrition program for mood and mental health
This trial tests a personalized nutrition program designed to improve mood and mental health. You'll use a smartphone app and receive meal plans based on your unique needs. It's for adults with mild to moderate depression who are ready to change their diet.
Bothell, WashingtonAges 25–75 - NCT06508450Recruiting
Mental health support for minority young adults
This trial tests a program to help racial and ethnic minority young adults engage with mental health services. It aims to improve access and participation in care.
The Bronx, New YorkAges 18–34 - NCT06512025Recruiting
Education program for first-time new mothers
This study tests whether a short education program (psychoeducational intervention) can help new first-time moms feel more confident and supported after childbirth. If you qualify, you would receive extra information and guidance during your postpartum checkups.
Barcelona, BarcelonaAges 18 years+ - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT06540664Recruiting
Ear acupuncture for post-stroke insomnia
This study tests whether auricular acupuncture (using small needles on the ear) can safely and effectively improve sleep in people who developed insomnia after a stroke. It's looking for participants who have had insomnia for at least 3 months since their stroke.
Ho Chi Minh CityAges 18 years+ - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT06546917Recruiting
Cognitive training trial for mild depression with brain scans
This trial tests a computer-based cognitive training program (bWell-D) to see if it can improve thinking skills like memory and focus in people with mild depression. You will also have an MRI brain scan to see how the training affects your brain.
Vancouver, British ColumbiaAges 19–55 - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06566937Recruiting
E-health program for mental health in breast cancer
This trial tests if an online program can improve mental health for breast cancer patients. It is designed for people currently receiving treatment at Institut Kanser Negara in Malaysia.
PutrajayaAges 18–65 - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06569303Recruiting
Filipino family health study for parents of children 8–12
This study offers a free parenting program for Filipino families with children ages 8–12 to help strengthen family bonds and manage challenges together. It is designed to understand what works best for your community.
Pasadena, CaliforniaAges 8 years+ - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+ - NCT06586619Recruiting
Tai chi and qigong for older adults with HIV
This study tests whether a remotely taught tai chi and qigong program can improve mood and well-being in people aged 50–75 who are living with HIV. You can join from home using a smartphone.
Miami, FloridaAges 50–75 - NCT06587230Recruiting
Tealeaf-NC: Teacher-led support for students in North Carolina
This study tests the Tealeaf program, where teachers and school staff work together to support students who may be struggling emotionally or behaviorally. It aims to help students in kindergarten through 8th grade who have elevated scores on a behavior and emotions questionnaire.
Chapel Hill, North CarolinaAges 5–99 - NCT06591663Recruiting
Does a therapy rating tool work across cultures?
This study tests whether a therapy rating scale, usually used in Western settings, works well in Pakistan. It aims to make the tool more relevant for local patients and therapists.
Lahore, Punjab ProvinceAges 18–65 - NCT06591676Recruiting
Translating a thinking habits questionnaire into Urdu
This trial is translating a questionnaire about negative thinking patterns (called the Dysfunctional Attitude Scale) into Urdu and testing it with people who have depression or anxiety. The goal is to make sure it works for Urdu-speaking communities in Pakistan.
Lahore, Punjab ProvinceAges 18–65 - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06606249Recruiting
Self-help coping skills for stressed university students
This trial tests a self-guided program, Self-Help Plus, to help university students manage stress and catch up with their studies. It may be helpful if you are behind on exams and feeling distressed.
Bari, BariAges 18 years+ - NCT06616116Recruiting
Stress Management with Real-Time Body Signal Feedback
This trial tests a stress management program that uses real-time feedback from your body signals (like heart rate). It is for people with mood disorders, such as depression or bipolar disorder, who also feel anxious or stressed. The goal is to help you learn to control your stress better.
Seoul, Jongno-guAges 15–59 - NCT06617663Recruiting
Online therapy for teens: is it as good as usual care?
This study compares online therapy (ACT or EMDR) to usual care for teens aged 12–18. It aims to see if online sessions work just as well as in-person treatment.
Alkmaar, North HollandAges 12–18 - NCT06627764Recruiting
Family program for Latino immigrant families with teens
This study tests a family-based program to help Latino immigrant parents and their teenagers (ages 12-17) build stronger relationships and address challenges together. It is designed for first-generation immigrant families who speak English or Spanish.
Durham, North CarolinaAges 12–100 - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,504 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.