Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06838286Recruiting
Study of triple therapy for type 2 diabetes
This study looks at the safety and effectiveness of adding a third oral diabetes medicine to your current two-drug combination. It is for adults with type 2 diabetes whose blood sugar is not well controlled on metformin plus one other pill.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06846138Enrolling by invitation
Herbal supplement to help metformin work better and cause fewer side effects
This study tests a special herbal blend added to metformin to see if it helps reduce stomach problems and improves blood sugar control in people with type 2 diabetes. Researchers want to understand how the herbs affect the bacteria in your gut.
RigaAges 25–80 - NCT06830096Recruiting
Understanding a key cell channel in type 2 diabetes
This study looks at how a specific channel in your cells (called the KATP channel) affects blood sugar control in people with and without type 2 diabetes. It aims to understand why some people develop diabetes and how to better treat it.
St Louis, MissouriAges 18–65 - NCT06820281RecruitingPhase 2
Tirzepatide effects on metabolism in type 1 diabetes
This trial tests whether tirzepatide, a medication that helps control blood sugar and weight, can safely improve how your body handles sugar when you have type 1 diabetes. The study looks at short-term effects and may help people who are overweight and use an insulin pump or automated system.
Sydney, New South WalesAges 18–70 - NCT06804187Enrolling by invitation
Sweet taste and type 2 diabetes study
This study looks at how sweet taste is sensed in people with type 2 diabetes, prediabetes, or no diabetes. It involves taste tests and possibly brain scans (MRI) to help understand why people with diabetes may perceive sweetness differently.
Nottingham, East MidlandsAges 18–60 - NCT06810635Recruiting
Polyphenol types in people with type 2 diabetes
This study looks at how different people process polyphenols (natural compounds in plant foods) based on their gut bacteria. It compares people with type 2 diabetes to those without diabetes to learn about possible health benefits.
Ghent, East FlandersAges 40–85 - NCT05439226Recruiting
Diet plan targeting liver fat for type 2 diabetes
This study tests whether a Chinese medical nutrition therapy diet can reduce liver fat and help manage type 2 diabetes in people who also have fatty liver. You may be asked to follow a specific eating plan and keep your diabetes care stable during the study.
Yichang, HubeiAges 18–75 - NCT06279637Recruiting
Diabetes support study for older African Americans and their caregivers
This study tests a joint program for older African Americans with type 2 diabetes and their caregivers. It aims to improve diabetes control through education and support sessions with a family member or friend.
Milwaukee, WisconsinAges 50–120 - NCT06752928Recruiting
Comparing CGM to finger-stick glucose checks in hospitalized adults with type 1 diabetes
This study compares a continuous glucose monitor (CGM) to standard finger-stick blood sugar checks in adults with type 1 diabetes while they are in the hospital and after they go home. It aims to see if using a CGM leads to better blood sugar control during and after hospitalization.
Atlanta, GeorgiaAges 18 years+ - NCT06752369Recruiting
Online program for teens with type 1 diabetes and depression
This study tests a short online program to help teens with type 1 diabetes who feel down. It aims to see if a few sessions can improve mood and diabetes management.
Orlando, FloridaAges 12–17 - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Tucson, ArizonaAges 10–17 - NCT06748963Recruiting
Fasted exercise training for type 1 diabetes
This study tests if exercising before breakfast (while fasting) helps improve blood sugar control and heart health in people with type 1 diabetes. You'll continue using your insulin pump and glucose monitor, and attend supervised exercise sessions and MRI scans to measure changes in your body.
Edmonton, AlbertaAges 18–55 - NCT06730906Enrolling by invitation
PACTAID app for managing exercise in type 1 diabetes
This study tests an app called PACTAID that helps adults with type 1 diabetes manage their blood sugar during exercise. You will try three different types of workouts to see how well the app works.
Rochester, MinnesotaAges 18–65 - NCT06734546Recruiting
Exercise and brain health in type 2 diabetes
This study tests whether regular exercise can improve brain health in people with type 2 diabetes. If you have type 2 diabetes, are not on insulin, are inactive, and are between 30 and 75 years old, you may be able to join.
Hasselt, LimburgAges 30–75 - NCT06081387Recruiting
Exercise and vitamin D for type 2 diabetes
This study tests whether adding aerobic and resistance exercise to your routine helps manage type 2 diabetes better when you already take metformin, an SGLT2 inhibitor, and possibly vitamin D. You would be assigned either to an exercise program or to continue your usual care.
BarcelonaAges 40 years+ - NCT06706284RecruitingPhase 4
GLP-1 agonist for diabetes after spinal cord injury
This trial tests whether a GLP-1 agonist (a type of diabetes medicine that also helps with weight loss) is safe and effective for people with spinal cord injury and type 2 diabetes who are not on other glucose-lowering drugs.
San Antonio, TexasAges 18–70 - NCT06694558Recruiting
Monocytes in type 1 diabetes and kidney disease study
This study looks at immune cells (monocytes) in people with type 1 diabetes, with or without early kidney problems. Researchers want to understand how these cells differ between groups. You may be able to join if you have type 1 diabetes and use an insulin pump or injections along with a continuous glucose monitor (CGM).
Cleveland, OhioAges 18–65 - NCT06683235Enrolling by invitation
Flaxseed for Type 2 Diabetes in Mexico
This trial tests if flaxseed can help control blood sugar in adults with type 2 diabetes. You may be able to join if you have diabetes that is not well-controlled and live in Oaxaca.
Oaxaca City, OaxacaAges 30–70 - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
Birmingham, AlabamaAges 18–50 - NCT06600555Recruiting
Metabolic surgery for diabetes control
This trial tests a type of weight-loss surgery (called metabolic surgery) to see if it helps people with type 2 diabetes achieve better blood sugar control. It's for people who have struggled to manage their diabetes with standard treatments and have a BMI between 30 and 35.
VilleurbanneAges 18–65 - NCT06613854RecruitingPhase 4
Early combination therapy for type 2 diabetes
This study tests if starting two newer diabetes drugs (empagliflozin and semaglutide) soon after diagnosis, along with metformin, helps control blood sugar better than metformin alone. It's for people diagnosed with type 2 diabetes in the last two years who are already taking a high dose of metformin.
LjubljanaAges 18–70 - NCT06588894Recruiting
Motor imagery and body awareness in type 2 diabetes
This study looks at how well people with type 2 diabetes can imagine movements, sense their body, and think clearly. It aims to understand how these abilities are affected by diabetes.
Kütahya, CentralAges 18–65 - NCT06575842Recruiting
Accuracy of glucose monitors during surgery in youth with type 1 diabetes
This trial tests how well continuous glucose monitors (CGMs) work during surgery and hospital stays in young people with type 1 diabetes. It aims to make sure these devices give accurate readings when they are most needed.
Aurora, ColoradoAges 2–26 - NCT06572345Recruiting
Low energy diet for teens with obesity and type 2 diabetes
This trial tests whether a low-energy diet using meal replacements can help teenagers with type 2 diabetes improve their blood sugar control. It involves a period of following the diet, then weight management, and includes follow-up visits.
NottinghamAges 12–17
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,155 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.