Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,190 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07716059Recruiting
Does legume flour in bread affect blood sugar?
This study tests how different sizes of legume flour in bread affect your body's blood sugar response. If you are a healthy adult or have type 2 diabetes, you may be able to participate.
Athens, AtticaAges 18–75 - NCT07053306RecruitingPhase 1
Study of SGLT2 inhibitor effects on ketoacidosis risk
This study looks at how stopping a common diabetes drug (SGLT2 inhibitor) affects the body's risk of a serious condition called ketoacidosis. It may help understand who is most at risk and how to prevent it.
San Antonio, TexasAges 30–75 - NCT05960656RecruitingPhase 1
Study of SGLT2 inhibitor effects on liver sugar production
This trial tests how stopping a type 2 diabetes medication called an SGLT2 inhibitor affects the liver's production of sugar and ketones. It may help understand better ways to manage diabetes.
San Antonio, TexasAges 30–75 - NCT07053293RecruitingEarly Phase 1
Study on diabetes medication and liver sugar production
This study tests how a type of diabetes medicine called SGLT2 inhibitors affects how the liver makes sugar. It may help researchers better understand how to manage blood sugar in people with type 2 diabetes.
San Antonio, TexasAges 30–75 - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Tuscaloosa, AlabamaAges 18 years+ - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT03228732RecruitingEarly Phase 1
Fluoxetine and/or DHEA in people with type 1 diabetes
This early-stage study tests whether the medicines fluoxetine and/or DHEA can improve health in adults with type 1 diabetes. It’s mainly looking for people without major diabetes complications or major medical problems to safely study the effects.
Baltimore, MarylandAges 18–50 - NCT03323216Recruiting
Testing heart-related blood markers in people with diabetes and heart failure
This study looks for blood markers that may help explain or predict heart problems in people who have type 2 diabetes and heart failure. To join, you may also need to be having a planned heart procedure where doctors can collect study information.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT03528226Recruiting
Exercise program to improve blood vessel function in type 1 diabetes
This trial studies whether an exercise training program can improve how well your blood vessels work in people with type 1 diabetes. It may help assess benefits beyond blood sugar control.
LilleAges 18–50 - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03710928Recruiting
Very low carbohydrate diet versus standard diet for type 1 diabetes
This study compares a very low carbohydrate diet to a regular diet to see how well blood sugar control works for adults with type 1 diabetes. It may help you understand which eating pattern is easier and safer for managing daily glucose with modern diabetes technology.
Boston, MassachusettsAges 18–40 - NCT03835312Recruiting
Transplant plan for children with genetic immune problems and diabetes
This trial tests a two-step transplant approach using immune-related stem cells and islet (pancreas insulin–making) cells in children and teens who have type 1 diabetes caused by a genetic immune problem. It aims to improve insulin control and protect other organs that are being affected by their immune system.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT03878706Recruiting
Testing diabetes medicines on heart risk and heart failure
This trial studies how diabetes medicines (GLP-1 and SGLT2, alone or together) affect the heart in people with type 2 diabetes who are at higher cardiovascular risk and have heart failure with preserved pumping function. It may help find safer or more effective ways to reduce heart problems.
Athens, AtticaAges 45–80 - NCT06884059RecruitingPhase 1
Time-restricted eating for people with early kidney signs
This study tests whether eating only during a certain window each day helps people with type 2 diabetes and small amounts of protein in their urine (a sign of early kidney stress) improve their health. You'll use a smartphone app to log your meals and follow a daily eating schedule.
La Jolla, CaliforniaAges 18–75 - NCT04109235Recruiting
Exercise training for adults with type 2 diabetes
This trial tests whether a structured, higher-intensity interval exercise program is safe and helpful for adults with type 2 diabetes. You might benefit through improved fitness and diabetes-related health, but you must be medically cleared to exercise.
Aylmer, OntarioAges 18 years+ - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Tucson, ArizonaAges 18 years+ - NCT04422366RecruitingPhase 3
9-valent HPV vaccine study for healthy Chinese women
This trial tests a 9-type HPV vaccine to see how well it works, how it helps the body build protection, and whether it’s safe. It’s for healthy Chinese women who have not had HPV vaccination before and meet specific health and timing requirements.
Liuzhou, GuangxiAges 20–45 - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT04869098Recruiting
Evening protein shake for night shift workers’ metabolic health
This study tests whether eating a protein preload in the evening (often called a protein “shake/meal” before sleep) can improve metabolic health in night shift workers. It aims to see if this timing and protein intake helps measures related to metabolism while working nights.
Adelaide, South AustraliaAges 35–65 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Charlotte, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,190 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.