Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07516509Recruiting
How muscle cells respond to blood sugar in different body types
This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.
Orlando, FloridaAges 30–65 - NCT07494084RecruitingPhase 4
How sleep loss and body clock disruption affect insulin resistance
This trial studies how losing sleep and disrupting your internal body clock may cause insulin resistance, a condition linked to diabetes. You will stay in a lab for several days to test your body's response to sleep changes and a morning drug called octreotide. The goal is to understand why shift work and jet lag can lead to health problems.
Spokane, WashingtonAges 18–45 - NCT06668935Recruiting
Using a continuous glucose monitor to help stick with GLP-1 meds
This study tests whether using a continuous glucose monitor (CGM) like the FreeStyle Libre 3 helps people with type 2 diabetes stay on their new GLP-1 or GIP/GLP-1 medication longer. You must be starting a GLP-1 or GIP/GLP-1 drug for the first time and not already using a CGM.
Jacksonville, FloridaAges 18 years+ - NCT07459582Recruiting
Home lactate meter and glucose meter accuracy in GSD
This study tests how well a home lactate meter and a standard blood sugar meter work for people with certain types of Glycogen Storage Disease (GSD Ia, Ib, or XI). If you or your child has one of these types, joining could help improve home monitoring.
Hartford, ConnecticutAges Up to 60 years - NCT06550596Recruiting
Amnion membrane for diabetic foot ulcers
This trial tests a wound covering made from donated amniotic tissue (dehydrated human amnion membrane) placed on a diabetic foot ulcer that isn't healing. It aims to see if adding this membrane to standard wound care helps the ulcer close faster.
Thousand Oaks, CaliforniaAges 18 years+ - NCT07378956Recruiting
AI eye screening for diabetes patients
This study uses an artificial intelligence (AI) tool to analyze eye images in people with type 2 diabetes. The goal is to see if the AI can help detect early signs of diabetic eye disease, so you can get the right care sooner.
Incheon, Gyeonggi-doAges 19 years+ - NCT07339852Recruiting
Pharmacist-led diabetes care in community pharmacies
This study tests whether a pharmacist-led program can help people with type 2 diabetes who are not meeting their blood sugar goals. The goal is to see if working with a pharmacist in your local pharmacy can improve your diabetes management.
Edmonton, AlbertaAges 18 years+ - NCT07298408RecruitingPhase 1/Phase 2
CBD for Diabetic Nerve Pain: A Pilot Study
This trial tests whether a daily dose of CBD (a cannabis compound) can help reduce nerve pain from type 2 diabetes. It's a small, early study to see if it's safe and effective.
Tallahassee, FloridaAges 40–70 - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT07245667RecruitingPhase 2
Tolnaftate stick for athlete's foot study
This trial tests a medicated stick for athlete's foot (tinea pedis). It aims to see if the treatment is safe and works well.
Framingham, MassachusettsAges 16 years+ - NCT06916663Recruiting
Upper body vs. combined exercise during diabetic foot ulcer treatment
This trial compares two exercise programs for people with diabetic foot ulcers: one that uses only upper body exercises and one that combines upper body with non-weight bearing lower body exercises. The goal is to see which approach helps healing while keeping weight off the foot.
CairoAges 18–65 - NCT07189936RecruitingPhase 2
Testing 2-HOBA for Immune Issues in Long COVID with POTS
This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.
Nashville, TennesseeAges 18 years+ - NCT07122726Recruiting
Balance exercises for fall prevention in diabetes
This study tests whether adding special movement exercises (called proprioceptive neuromuscular facilitation) to standard Otago exercises can help improve balance and reduce the risk of falls in people with type 2 diabetes who have nerve damage in their feet.
IslamabadAges 50–75 - NCT07022418RecruitingPhase 2
Formoterol for diabetic kidney disease
This trial tests if a drug called formoterol (usually used for asthma) can help protect the kidneys in people with type 2 diabetes and early-to-moderate kidney disease. It may offer a new way to slow kidney damage.
Charleston, South CarolinaAges 18–75 - NCT04916457Recruiting
Studying skin germs in diabetes-related foot skin problems
This study collects skin samples from people with and without type 2 diabetes, especially around foot skin problems, to learn how skin “micro-germs” differ. The goal is to better understand what’s going on in diabetic skin lesions and possibly guide future care.
Guangzhou, GuangdongAges 18–80 - NCT06790537RecruitingPhase 4
Pregabalin for itching in diabetes: a controlled study
This trial tests if pregabalin can reduce chronic itching in people with type 2 diabetes. It compares pregabalin against a placebo (inactive pill) to see if itching improves more with the active drug.
Chandigarh, ChandigarhAges 18 years+ - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Aurora, ColoradoAges Any age - NCT05761223RecruitingPhase 1/Phase 2
Study of FB849 for adults with measurable cancer lesions
This early-stage trial tests whether FB849 is safe and tolerable, how the body handles it, and whether it shows any early signs of helping cancer. You may be able to join if you’re an adult with at least one measurable tumor spot and your health tests meet study requirements.
Cleveland, OhioAges 18 years+ - NCT05802329RecruitingPhase 1
Testing eye injections for diabetic macular swelling
This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.
Deerfield Beach, FloridaAges 18 years+ - NCT05057403Recruiting
Imaging study for adults with type 2 diabetes in the UK
This study uses medical scans (MRI) to better understand diabetes in the body, including the eyes, and how it may change over time. It may help improve how diabetes is monitored, especially for people with diabetic eye disease.
Didcot, OxfordshireAges 18 years+ - NCT05654467RecruitingPhase 2
Oral polio vaccine study for young children in Panama
This trial tests a new oral polio vaccine in children and babies in Panama. The goal is to see if it is safe and helps the body build protection against polio.
Panama CityAges 1 day–4 years - NCT05544019RecruitingPhase 1
Testing an investigational drug for mature B-cell cancers
This early (Phase 1) study tests SGR-1505, an experimental treatment, in people with certain mature B-cell cancers. It’s mainly designed to see how the drug works in the body and to check safety, and it may offer an option if standard treatments aren’t enough.
Gilbert, ArizonaAges 18 years+ - NCT05074342Enrolling by invitation
Project Open study to improve eye screening for diabetes
This study uses health records to see how to increase eye exam screening for people with diabetes who may be at risk of diabetic retinopathy. It aims to help more people get timely eye checks to prevent vision problems.
Toronto, OntarioaAges 18 years+ - NCT04941599RecruitingPhase 2
2-HOBA to improve “good cholesterol” function in FH
This Phase 2 trial tests whether 2-HOBA can improve how “good cholesterol” (HDL) works in people with familial hypercholesterolemia (FH). If HDL works better, it may help lower heart risk markers. You would need to meet several heart, health, and medication-related safety checks.
Nashville, TennesseeAges 18–69
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,152 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.