Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,190 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+ - NCT06269419Recruiting
Diabetes eye disease natural progression study
This study follows people with type 2 diabetes to understand how diabetic retinopathy (an eye disease caused by diabetes) changes over time without treatment. It may help if you have no other eye issues causing new blood vessels and are not planning for certain eye procedures.
Chengdu, SichuanAges 18–75 - NCT07295704Recruiting
Micropulse laser for diabetic macular edema
This trial tests a special laser treatment for diabetic macular edema, a swelling in the back of the eye caused by diabetes. It aims to see if the laser can help patients who have not improved with standard treatment.
CairoAges 18 years+ - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT07242300RecruitingPhase 3
Testing a new botulinum toxin for arm stiffness after stroke
This trial tests a new injectable medication (Eveotox) to see if it can safely reduce arm or hand stiffness in people who have had a stroke. The goal is to improve daily activities like dressing or cleaning your hand.
Beijing, Beijing MunicipalityAges 18–80 - NCT07747454Recruiting
Strength exercises or electrical stimulation for diabetic frozen shoulder
This study tests two types of physical therapy—isometric strengthening exercises and TENS (a pain-relieving electrical stimulation)—to see which is better for reducing pain and improving movement in people with diabetes who have frozen shoulder. You may receive one of these treatments for several weeks.
Kafr ash ShaykhAges 40–65 - NCT07676188Recruiting
Diabetes help with finances and social needs (LINKD)
This study tests whether connecting people with diabetes to a peer supporter and social services can improve blood sugar control. It is for adults who have type 1 or type 2 diabetes, struggle with costs or basic needs, and want help.
Ann Arbor, MichiganAges 18 years+ - NCT07161830Recruiting
Skin repair treatment for diabetic foot ulcers
This study tests a special skin repair matrix for diabetic foot ulcers that are not healing well with standard care. The treatment may help the wound close and heal faster.
Evergreen Park, IllinoisAges 18 years+ - NCT07082725RecruitingPhase 3
Study of oral nizubaglustat for Niemann-Pick type C
This study tests an oral medication called nizubaglustat for people with Niemann-Pick type C disease who cannot take or are not satisfied with the current treatment miglustat. It aims to see if the drug can help with symptoms like coordination and movement problems.
Oakland, CaliforniaAges 4 years+ - NCT06729996RecruitingPhase 2
Comparing two diabetes medicines for pancreatitis-related diabetes
This trial tests whether pioglitazone or empagliflozin is better at managing diabetes caused by chronic or recurrent pancreatitis. You will take one of these pills daily for 6 months and track your blood sugar and ketones at home. The goal is to find a safer, more effective treatment for this type of diabetes.
Rochester, MinnesotaAges 18–80 - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT07726043Recruiting
Rehab with vibration therapy for balance in CMT1A
This trial tests whether adding a special vibration device to an intensive rehab program helps improve balance in people with Charcot-Marie-Tooth disease type 1A. If you are between 18 and 65 and have mild to moderate leg weakness, you may be able to join.
MarseilleAges 18–65 - NCT05079399Recruiting
Diabetic eye screening study using eye scans
This study looks for specific eye findings (“biomarkers”) in people with type 2 diabetes using eye imaging. It may help researchers better understand diabetic retinopathy and how to detect it earlier or more accurately.
Carmel, IndianaAges 18 years+ - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT03687580Recruiting
At-home laser treatment for diabetic foot ulcers
This trial tests whether an at-home low-level laser can help diabetic foot ulcers heal. You may be able to do treatments yourself or with a caregiver, but you must meet specific wound, circulation, and safety requirements.
Toronto, OntarioAges 18–95 - NCT03716401Recruiting
Imaging tests to predict kidney disease in type 2 diabetes
This study uses special kidney imaging to look for patterns that can predict how diabetic kidney disease may progress. It may help researchers find better ways to identify people at higher risk using noninvasive (and possibly biopsy-related) tests.
TurkuAges 18–80 - NCT03865290RecruitingPhase 2
Ondansetron for stomach nerve and motion problems in diabetes
This trial tests whether ondansetron can improve stomach “sensorimotor” problems—how the gut senses food and moves it—especially in people with diabetes and troubling indigestion. It may help reduce symptoms like early fullness, nausea, and discomfort after eating.
Rochester, MinnesotaAges 18–75 - NCT03944876RecruitingPhase 3
Botulinum toxin to block a facial nerve for chronic cluster headaches
This trial tests whether injections of botulinum toxin type A can reduce frequent, severe cluster headache attacks by targeting a facial nerve area. It’s for people whose cluster headaches have not responded well—or have caused side effects—to standard preventive treatments.
HamburgAges 18–85 - NCT06969807RecruitingPhase 2
Stem cells for diabetic kidney disease
This trial tests whether a type of stem cell called mesenchymal stromal cells (Amimestrocel) can help people with diabetic kidney disease. It aims to see if the treatment is safe and can improve kidney function.
Beijing, Beijing MunicipalityAges 18–80 - NCT04073706RecruitingPhase 3
Checking lymph nodes with a tracer during endometrial cancer surgery
This trial tests a “sentinel node” biopsy, using a special dye/tracer, during surgery for early-stage endometrial cancer. It may help doctors find whether cancer has spread to lymph nodes while possibly avoiding more extensive lymph node removal.
Houston, TexasAges 18 years+ - NCT04141878Recruiting
Lifestyle program to help prevent dementia in adults with diabetes risk
This trial tests a structured lifestyle program (more activity and healthier eating) to help prevent or slow memory and thinking problems. It may be helpful if you’re older but not showing major memory impairment, and you can commit to weekly study activities for about 8 months.
Walnut Creek, CaliforniaAges 60 years+ - NCT04240652Recruiting
Diabetes eye screening and prevention program for eye disease
This program aims to screen people for diabetic eye problems early and help prevent vision loss over time. It may help you if you have type 2 diabetes (or you’ve been invited as a diabetes/non-diabetes participant) and can safely take part in the study activities.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04270578Recruiting
Study of gestational diabetes during pregnancy and after birth
This trial looks at gestational diabetes (high blood sugar during pregnancy) and may study how it’s managed during pregnancy and postpartum. It may help researchers understand what approaches are safe and useful for people with this condition.
TübingenAges 18 years+ - NCT04512716RecruitingEarly Phase 1
Radioimmunotherapy then CD19 CAR T for hard-to-treat blood cancers
This early-phase study tests a two-step treatment: first a targeted radioactive antibody (131-I apamistamab) and then CD19 CAR T-cell therapy. It is for adults with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) or diffuse large B-cell lymphoma (DLBCL) that is not responding or has come back, aiming to shrink cancer using engineered immune cells.
Basking Ridge, New JerseyAges 18 years+
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,190 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.