Clinical trials · Illinois
Diabetes clinical trials in Illinois
We’re tracking 94 recruiting diabetes studies with a site in Illinois — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Schaumburg, IllinoisAges 18 years+ - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Skokie, IllinoisAges 18 years+ - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Oak Forest, IllinoisAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Chicago, IllinoisAges 14–75 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Skokie, IllinoisAges 18 years+ - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Chicago, IllinoisAges 18–75 - NCT07415954RecruitingPhase 2
Testing a new diabetes medicine for blood sugar control
This study tests a new medicine, NNC0662-0419, in people with type 2 diabetes. You must be willing to lose a lot of weight (more than a quarter of your current weight) as part of the study to see if the medicine helps lower blood sugar.
Chicago, IllinoisAges 18–75 - NCT07396376RecruitingPhase 1/Phase 2
Testing ELU42 spray for diabetic foot ulcers
This study tests a new topical spray (ELU42) to help heal diabetic foot ulcers. It may be a good option if you have a non-infected, non-ischemic ulcer and your blood sugar is reasonably controlled.
O'Fallon, IllinoisAges 18–75 - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Springfield, IllinoisAges 18 years+ - NCT07351318Enrolling by invitation
Insulin sensitivity in type 1 diabetes pregnancies
This study looks at how well the body uses insulin in women who had type 1 diabetes during a recent pregnancy. If you used a Dexcom CGM and Tandem insulin pump while pregnant, your data could help researchers better understand insulin needs in pregnancy.
Chicago, IllinoisAges 18 years+ - NCT05208164Recruiting
Mindfulness program for Black adults with type 2 diabetes
This study tests whether a mindfulness class, delivered by text messages and online or in-person sessions, can help adults with type 2 diabetes. It is designed specifically for African American/Black participants in the Chicago area.
Chicago, IllinoisAges 21–75 - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Chicago, IllinoisAges 18–75 - NCT07296952Recruiting
Improving transportation for diabetic retinopathy patients
This study tests a new way to help people with diabetic retinopathy get to their eye appointments. It aims to make transportation easier for patients who have Medicaid insurance.
Chicago, IllinoisAges 18 years+ - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Chicago, IllinoisAges 18 years+ - NCT07282613RecruitingPhase 3
CagriSema for blood sugar and weight in children with type 2 diabetes
This study tests a new medicine called CagriSema to see if it can lower blood sugar and help with weight loss in children and teens with type 2 diabetes. It compares the medicine to a placebo (a look-alike with no active drug) over several months.
Springfield, IllinoisAges 10–18 - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Chicago, IllinoisAges 18 years+ - NCT07271186RecruitingPhase 2
Study of an experimental drug for kidney disease from type 2 diabetes
This study tests an investigational drug called ALN-ANG3 to see if it can help people with diabetic kidney disease. The drug may reduce kidney damage and slow down the loss of kidney function. If you join, you will get the study drug or a placebo (a dummy shot) and be followed by a study doctor.
Chicago, IllinoisAges 18–80 - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Tinley Park, IllinoisAges 18–80 - NCT07161830Recruiting
Skin repair treatment for diabetic foot ulcers
This study tests a special skin repair matrix for diabetic foot ulcers that are not healing well with standard care. The treatment may help the wound close and heal faster.
Evergreen Park, IllinoisAges 18 years+ - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+ - NCT06989008Recruiting
Improving diabetes care with wearable sensors
This study tests if wearing two devices (a continuous glucose monitor and a sports wristband) can help improve diabetes care. It focuses on people with type 2 diabetes who live in certain Chicago neighborhoods and are willing to use the devices.
Chicago, IllinoisAges 18–65 - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Chicago, IllinoisAges 18–50 - NCT06915831Recruiting
Type 1 diabetes and sleep apnea study
This study looks at how sleep apnea affects blood sugar control in adults with type 1 diabetes. It may help researchers understand if treating sleep apnea improves diabetes management.
Chicago, IllinoisAges 18–50
Diabetes trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting diabetes studies listed above.
- Northwestern University · 4 studies
- Cedar-Crosse Research Center · 2 studies
- Accellacare of Duly
- Accellacare of Duly - Lombard
- AES - DRS - Synexus Clinical Research US, Inc. - Chicago
- AURORA-2 Clinical Site
- Cedar Crosse Research Center
- Central Illinois Diabetes and Clinical Research
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Illinois?
- Yes. We're currently tracking 94 recruiting diabetes studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.