Clinical trials · Massachusetts
Diabetes clinical trials in Massachusetts
We’re tracking 98 recruiting diabetes studies with a site in Massachusetts — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07011147Recruiting
Real-world test of automated insulin delivery in primary care
This study tests if an automated insulin delivery system (the iLet bionic pancreas) works well in real-world primary care settings for people with type 1 or type 2 diabetes. It aims to see if this technology can help manage blood sugar more easily.
Boston, MassachusettsAges 18–89 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Boston, MassachusettsAges 12–35 - NCT04629586Recruiting
T1D Exchange registry for people with type 1 diabetes
This trial registry collects information about people living with type 1 diabetes to help researchers better understand the condition. It may help by allowing future studies and improving how care is studied and planned.
Boston, MassachusettsAges Any age - NCT07271043Recruiting
High-protein drink for weight loss in type 2 diabetes
This study tests if a high-protein diabetes shake can help people with type 2 diabetes who are starting a new class of diabetes medications (GLP-1 or GIP receptor agonists) lose weight and improve body composition. Participants will either take the shake or a placebo drink for several weeks.
Boston, MassachusettsAges 18–75 - NCT07197775Enrolling by invitation
Endogenex PULSE Registry: Tracking long-term outcomes
This registry collects information from people with type 2 diabetes who have already been treated with the Endogenex System. It helps researchers learn how the treatment works over time.
Quincy, MassachusettsAges 18 years+ - NCT07197788Enrolling by invitation
Continued access to the Endogenex device study for type 2 diabetes
This trial offers continued access to the Endogenex system for people who were in the sham (placebo) group of the ReCET study and have completed their 12-month visit. It tests a device that treats the duodenum to improve blood sugar control.
Quincy, MassachusettsAges 22 years+ - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Boston, MassachusettsAges 18–75 - NCT06104969Recruiting
Biomarkers for active diabetic foot ulcers
This study is looking for people with diabetes who have an open foot or ankle ulcer. Researchers want to collect samples to find biomarkers, which are natural signs in the body that could help improve treatment and healing. It may be a good fit if you have a diabetic foot ulcer and are not currently in another drug trial for ulcers.
Boston, MassachusettsAges 18 years+ - NCT07797335RecruitingPhase 3
Zenagamtide for diabetes and weight loss
This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.
Boston, MassachusettsAges 45 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Braintree, MassachusettsAges 18 years+ - NCT07632001Recruiting
Miro3D Wound Matrix for Diabetic Foot Ulcers
This trial tests a new wound-healing product called Miro3D to help diabetic foot ulcers heal better. You would receive this product along with standard wound care to see if it helps your ulcer close faster than standard treatment alone.
Hyde Park, MassachusettsAges 18 years+ - NCT07468188Recruiting
Diabetes Body Project: Body image support for women with type 2 diabetes
This study tests a program to help women with type 2 diabetes feel better about their body image. You'll attend group sessions that focus on improving how you see and feel about your body.
Boston, MassachusettsAges 18–40 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Boston, MassachusettsAges 8–45 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Boston, MassachusettsAges Any age - NCT06236607Recruiting
Artificial pancreas trial for adults with type 1 diabetes
This trial tests a hybrid closed-loop system that automatically adjusts insulin delivery. It may help you manage your blood sugar more easily if you currently give yourself daily insulin shots.
Boston, MassachusettsAges 18–75 - NCT05388643Recruiting
Early screening for gestational diabetes during early pregnancy
This study tests whether checking for gestational diabetes (diabetes that starts in pregnancy) early can help identify it sooner in people at higher risk. You may be asked to do a glucose test during your first prenatal visits so clinicians can monitor and respond earlier.
Worcester, MassachusettsAges 18 years+ - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Boston, MassachusettsAges 18 years+ - NCT06141434Recruiting
Maternal Exposures and Baby Diabetes Risk Study
This study follows pregnant women and their babies to learn how early-life factors may affect the risk of type 1 diabetes. If your baby has a parent or sibling with type 1 diabetes, you may be able to join.
Boston, MassachusettsAges birth–99 years - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
North Dartmouth, MassachusettsAges 18 years+ - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Boston, MassachusettsAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Methuen, MassachusettsAges 18–79 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Boston, MassachusettsAges 14–75 - NCT07567833RecruitingPhase 4
Tracking Eye Function After Diabetes Swelling Treatment
This study follows patients with diabetic eye swelling (a complication of diabetes affecting the macula, the part of your eye needed for detailed vision) who are receiving anti-VEGF injections—a standard treatment that reduces abnormal blood vessel growth. Researchers will measure how well your retina (the light-sensitive tissue in your eye) recovers and functions over time.
Boston, MassachusettsAges 18 years+ - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Boston, MassachusettsAges 18–75
Diabetes trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting diabetes studies listed above.
- Joslin Diabetes Center · 8 studies
- Research Site · 3 studies
- Care Access · 2 studies
- ACCOMPLISH-2 Research Site
- Beth Israel Deaconess Medical Center
- Boston Medical Center
- Boston Medical Center Corporation
- Brigham and Women's Hospital
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Massachusetts?
- Yes. We're currently tracking 98 recruiting diabetes studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.