Clinical trials · Massachusetts
Diabetes clinical trials in Massachusetts
We’re tracking 95 recruiting diabetes studies with a site in Massachusetts — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07011147Recruiting
Real-world test of automated insulin delivery in primary care
This study tests if an automated insulin delivery system (the iLet bionic pancreas) works well in real-world primary care settings for people with type 1 or type 2 diabetes. It aims to see if this technology can help manage blood sugar more easily.
Boston, MassachusettsAges 18–89 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Boston, MassachusettsAges 12–35 - NCT07197788Enrolling by invitation
Continued access to the Endogenex device study for type 2 diabetes
This trial offers continued access to the Endogenex system for people who were in the sham (placebo) group of the ReCET study and have completed their 12-month visit. It tests a device that treats the duodenum to improve blood sugar control.
Quincy, MassachusettsAges 22 years+ - NCT04629586Recruiting
T1D Exchange registry for people with type 1 diabetes
This trial registry collects information about people living with type 1 diabetes to help researchers better understand the condition. It may help by allowing future studies and improving how care is studied and planned.
Boston, MassachusettsAges Any age - NCT06104969Recruiting
Biomarkers for active diabetic foot ulcers
This study is looking for people with diabetes who have an open foot or ankle ulcer. Researchers want to collect samples to find biomarkers, which are natural signs in the body that could help improve treatment and healing. It may be a good fit if you have a diabetic foot ulcer and are not currently in another drug trial for ulcers.
Boston, MassachusettsAges 18 years+ - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Boston, MassachusettsAges 18–75 - NCT07271043Recruiting
High-protein drink for weight loss in type 2 diabetes
This study tests if a high-protein diabetes shake can help people with type 2 diabetes who are starting a new class of diabetes medications (GLP-1 or GIP receptor agonists) lose weight and improve body composition. Participants will either take the shake or a placebo drink for several weeks.
Boston, MassachusettsAges 18–75 - NCT07197775Enrolling by invitation
Endogenex PULSE Registry: Tracking long-term outcomes
This registry collects information from people with type 2 diabetes who have already been treated with the Endogenex System. It helps researchers learn how the treatment works over time.
Quincy, MassachusettsAges 18 years+ - NCT07632001Recruiting
Miro3D Wound Matrix for Diabetic Foot Ulcers
This trial tests a new wound-healing product called Miro3D to help diabetic foot ulcers heal better. You would receive this product along with standard wound care to see if it helps your ulcer close faster than standard treatment alone.
Hyde Park, MassachusettsAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Braintree, MassachusettsAges 18 years+ - NCT05388643Recruiting
Early screening for gestational diabetes during early pregnancy
This study tests whether checking for gestational diabetes (diabetes that starts in pregnancy) early can help identify it sooner in people at higher risk. You may be asked to do a glucose test during your first prenatal visits so clinicians can monitor and respond earlier.
Worcester, MassachusettsAges 18 years+ - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Boston, MassachusettsAges Any age - NCT06236607Recruiting
Artificial pancreas trial for adults with type 1 diabetes
This trial tests a hybrid closed-loop system that automatically adjusts insulin delivery. It may help you manage your blood sugar more easily if you currently give yourself daily insulin shots.
Boston, MassachusettsAges 18–75 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Boston, MassachusettsAges 8–45 - NCT07468188Recruiting
Diabetes Body Project: Body image support for women with type 2 diabetes
This study tests a program to help women with type 2 diabetes feel better about their body image. You'll attend group sessions that focus on improving how you see and feel about your body.
Boston, MassachusettsAges 18–40 - NCT07270133Recruiting
Diabetes eye health observation study
This study observes how diabetes affects vision over time in people with diabetes. It helps doctors better understand eye health without any treatment or intervention.
Boston, MassachusettsAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Malden, MassachusettsAges 18 years+ - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Springfield, MassachusettsAges 18–75 - NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74 - NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Boston, MassachusettsAges 6–17 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Methuen, MassachusettsAges 18–79 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Worcester, MassachusettsAges 40–80 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Waltham, MassachusettsAges 18–80 - NCT07449936RecruitingPhase 3
Comparing a new long-lasting injection to standard one for DME
This phase 3 trial tests a new long-acting injection (EYP-1901) against a standard one (aflibercept) for people with diabetic macular edema. Both treatments are given as eye injections, and the goal is to see if the new drug works as well and may require fewer injections.
Springfield, MassachusettsAges 18 years+
Diabetes trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting diabetes studies listed above.
- Joslin Diabetes Center · 6 studies
- Boston Medical Center · 2 studies
- Care Access · 2 studies
- Massachusetts General Hospital · 2 studies
- University of Massachusetts Chan Medical School · 2 studies
- ACCOMPLISH-2 Research Site
- ActivMed Practices and Research
- Beth Israel Deaconess Medical Center
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Massachusetts?
- Yes. We're currently tracking 95 recruiting diabetes studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.