Clinical trials · Tennessee
Diabetes clinical trials in Tennessee
We’re tracking 62 recruiting diabetes studies with a site in Tennessee — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Tennessee
- NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Chattanooga, TennesseeAges 12–35 - NCT06609356RecruitingEarly Phase 1
Reducing high insulin levels in type 1 diabetes
This study tests if adding a non-insulin medication can lower the amount of insulin needed while improving heart and metabolic health in people with type 1 diabetes. It may also help understand how this approach works in people with a genetic form of diabetes (GCK-MODY).
Nashville, TennesseeAges 18–60 - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Chattanooga, TennesseeAges 7–85 - NCT07284901RecruitingPhase 3
Weekly injection for diabetes and weight loss
This study tests an experimental once-weekly injection called ribupatide for people with type 2 diabetes and overweight. It aims to help them lose weight and better control their blood sugar.
Chattanooga, TennesseeAges 18 years+ - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Memphis, TennesseeAges 18 years+ - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Nashville, TennesseeAges Any age - NCT05930210RecruitingPhase 3
Study gel treatment for diabetic foot ulcers that won’t heal
This Phase 3 trial tests ENERGI-F703 gel to help heal diabetic foot ulcers that have not improved for at least 4 weeks. It may help some people whose wounds meet specific size and non-infection criteria.
Jackson, TennesseeAges 18 years+ - NCT06516614Recruiting
Sleep coaching for teens with type 1 diabetes
This study is testing a sleep coaching program for teenagers with type 1 diabetes who aren't getting enough sleep and have above-target blood sugar. The program aims to help them sleep better and possibly improve diabetes control.
Nashville, TennesseeAges 11–17 - NCT06852950Recruiting
CGM for diabetes management after hospital discharge
This trial tests if using a continuous glucose monitor (CGM) after leaving the hospital helps manage diabetes. You wear a small sensor on your arm that checks your sugar levels all day and sends them to your phone.
Nashville, TennesseeAges 18 years+ - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Nashville, TennesseeAges 8–45 - NCT07565727Recruiting
Heart Health and Metabolism in Early Pregnancy
This study looks at how the body processes sugar and nutrients during pregnancy in women at higher risk for pre-eclampsia (a serious pregnancy condition with high blood pressure). Researchers want to understand if taking low-dose aspirin helps protect heart and metabolic health. You'll have blood tests, body composition scans, and metabolic measurements.
Knoxville, TennesseeAges 18–45 - NCT07754461RecruitingPhase 3
Survodutide for blood sugar control in type 2 diabetes
This study tests an investigational drug called survodutide to see if it helps people with type 2 diabetes manage their blood sugar levels. Participants will receive either survodutide or a placebo, and the study will compare changes in HbA1c (a measure of blood sugar control).
Chattanooga, TennesseeAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Knoxville, TennesseeAges 18 years+ - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Chattanooga, TennesseeAges 18–75 - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Memphis, TennesseeAges 18 years+ - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Germantown, TennesseeAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Bartlett, TennesseeAges 1–25 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Nashville, TennesseeAges 18–79 - NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Memphis, TennesseeAges 18–75 - NCT07271186RecruitingPhase 2
Study of a New Drug for Diabetic Kidney Disease
This study tests an investigational drug that blocks a protein called ANGPTL3, which may help protect the kidneys in people with type 2 diabetes and diabetic kidney disease. It aims to see if the drug can reduce kidney damage and improve overall health.
Chattanooga, TennesseeAges 18–80 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Nashville, TennesseeAges 40–80 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Nashville, TennesseeAges 18–80 - NCT07449936RecruitingPhase 3
Comparing a new long-lasting injection to standard one for DME
This phase 3 trial tests a new long-acting injection (EYP-1901) against a standard one (aflibercept) for people with diabetic macular edema. Both treatments are given as eye injections, and the goal is to see if the new drug works as well and may require fewer injections.
Nashville, TennesseeAges 18 years+ - NCT07449923RecruitingPhase 3
Comparing a new injection to standard treatment for diabetic macular edema
This trial compares a new treatment (EYP-1901, given as an injection) to a standard injection (aflibercept) for people with diabetic macular edema. It aims to see which works better at reducing swelling and improving vision.
Germantown, TennesseeAges 18 years+
Diabetes trials by city in Tennessee
Where these studies are running in Tennessee
Institutions with a site for the recruiting diabetes studies listed above.
- Vanderbilt University Medical Center · 7 studies
- University Diabetes & Endocrine Consultants · 4 studies
- Charles Retina Institute · 2 studies
- LifeDoc Health · 2 studies
- Research Site · 2 studies
- Alliance for Multispecialty Research
- AM Diabetes & Endocrinology Center
- AMR Clinical
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Tennessee?
- Yes. We're currently tracking 62 recruiting diabetes studies with a site in Tennessee, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Tennessee?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Tennessee to take part?
- Not necessarily. These studies have a site in Tennessee, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Tennessee regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.