Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02925819Recruiting
Study for severe mitral valve disease when surgery isn’t an option
This trial focuses on people with severe mitral valve narrowing or leaking who still have symptoms even after the best usual medications. It may help find better care and measure health outcomes when surgery is judged too risky or not suitable.
LyonAges 18 years+ - NCT03329274Recruiting
Histiocytosis patient registry for Erdheim-Chester and related diseases
This is a registry (a research database) for people with Erdheim-Chester disease and other related “histiocytosis” conditions. It collects past and future medical information to better understand these illnesses and support future research.
New York, New YorkAges 18 years+ - NCT02929732Recruiting
Study muscle nerve activity in restless legs
This study looks at how active the nerves are in people with Willis-Ekbom disease (restless legs syndrome) and compares them with people without it. It may help researchers understand what drives symptoms and how the condition works in the body.
MontpellierAges 18–74 - NCT03203239Recruiting
Red light treatment for circulation problems in leg arteries
This study tests whether a red-light therapy can improve symptoms or function in people with peripheral artery disease (poor blood flow to the legs). You may qualify if your leg circulation test is abnormal and you can safely take part in the study.
Milwaukee, WisconsinAges 18–85 - NCT03178630Recruiting
MRI scans to track outcomes in children with autoimmune liver disease
This study uses MRI scans to find “biomarkers,” or imaging clues, that may help predict how autoimmune liver conditions will progress in children and young adults. If you qualify, you may get MRI imaging to see whether it relates to future health outcomes.
Cincinnati, OhioAges 6–23 - NCT03014609Recruiting
Testing cardiovascular risk in people with COPD
This trial studies cardiovascular (heart and blood vessel) risk in people who have stable COPD or a recent worsening of COPD. It may help researchers understand which risks to monitor during and after a COPD flare and how to prevent complications.
Grenoble, La TroncheAges 18–85 - NCT03011697Recruiting
Heart valve disease registry for adults
This study enrolls adults in the hospital with certain heart valve problems to track their health over time. It may help doctors better understand how valve disease behaves and what outcomes look like in real life.
Hangzhou, ZhejiangAges 18 years+ - NCT03035851Recruiting
Exercise program for older adults at risk of memory decline
This trial tests whether a structured aerobic (heart-pumping) exercise program can improve memory and thinking in older adults who feel memory trouble but have not been diagnosed with dementia. It focuses on people who are “at increased risk” due to common health factors like high blood pressure or diabetes.
Calgary, AlbertaAges 50–80 - NCT07377565RecruitingPhase 1
Testing a new diagnostic for celiac disease during endoscopy
This study tests a new medicine called HB-2121 used as a diagnostic tool during an upper endoscopy to help improve detection of celiac disease. It's designed for people who are already scheduled for this procedure and may help doctors see the gut damage caused by celiac more clearly.
Stanford, CaliforniaAges 18 years+ - NCT05699018Recruiting
Screening people with liver scarring in primary care
This study tests how well primary care doctors can screen for advanced liver scarring in people with fatty liver from non-alcohol causes or from alcohol use. It may help find liver problems earlier so you can get the right follow-up.
AngersAges 40–80 - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07614659Recruiting
Heart health screening for adults in Uppsala, Sweden
This study invites residents of Uppsala, Sweden who are turning 50, 55, 60, 65, 70, or 75 to participate in cardiovascular (heart and blood vessel) health screening. The goal is to help identify heart health risks early so you can take steps to stay healthy.
UppsalaAges 50–75 - NCT07616687RecruitingPhase 4
Testing guselkumab to improve Crohn's disease control
This study tests whether guselkumab, a newer biologic medication, can better control active Crohn's disease symptoms and inflammation. You'll receive the medication and be monitored closely to see how well it works for you.
AmiensAges 18 years+ - NCT07533890Recruiting
Probiotics and gut health in children with inflammatory bowel disease
This study tests whether a multi-strain probiotic supplement can change the gut bacteria in children and teens with inflammatory bowel disease (IBD). Researchers will collect stool samples to see if the probiotics help restore healthy gut bacteria and potentially improve symptoms.
BernAges 5–18 - NCT03388476Enrolling by invitation
Breathing carbon dioxide measurement to detect lung high blood pressure
This trial tests whether measuring carbon dioxide you breathe out can help detect pulmonary hypertension earlier. It may help doctors spot this lung blood vessel condition sooner, especially around the time you get a heart test.
Giessen, HesseAges 18 years+ - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50 - NCT02751060Enrolling by invitation
Blood test for RNA signals to track coronary heart disease
This study checks whether tiny RNA signals found in a blood sample can help identify or monitor coronary heart disease. It may help doctors learn better ways to recognize the condition and track changes soon after symptoms begin.
Wuhan, HubeiAges 18 years+ - NCT02422875Enrolling by invitation
Study of immune markers in autoimmune disease and lupus
This study looks at blood and immune cell markers (autoantibodies and immune cell “signatures”) to better understand autoimmune conditions, including lupus. It may help researchers identify which markers are linked to disease and how immune cells respond after vaccination.
Atlanta, GeorgiaAges 18 years+ - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT02471170Enrolling by invitation
Taking blood samples for pancreatic and related cancer research
This study asks people receiving care at the University of Pennsylvania Hospital to provide samples that can help researchers study tumor material. If you have pancreatic disease—or you’re getting care for something else (like a routine colonoscopy)—your samples may be used to compare findings and improve future research.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02422238Recruiting
Study of fatty liver in adults, using MRI and stored samples
This study follows people with nonalcoholic fatty liver disease to better understand the condition. It uses an MRI scan and collects body samples to help researchers study changes over time.
Maastricht, LimburgAges 18–65 - NCT02848131Enrolling by invitationPhase 2
Testing dasatinib and quercetin in diabetes-related kidney disease
This study tests whether two medicines (dasatinib and quercetin) can affect “cell aging” in people with chronic kidney disease related to diabetes. You may be asked to take pills for a short period and complete follow-up visits to measure how your body responds.
Jacksonville, FloridaAges 40–80
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.