Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01803906Enrolling by invitation
Tissue sample study for suspected mitochondrial disorders
This study collects tissue samples to help researchers learn more about mitochondrial disorders—conditions related to how the body makes energy. It may help by improving genetic understanding for families who suspect an inherited cause.
New York, New YorkAges Any age - NCT00983463Enrolling by invitation
Study of liver fats and proteins in fatty liver disease
This study measures different fats and proteins in the liver of people with fatty liver disease (often called NAFLD) who are having planned abdominal or weight-loss surgery. It may help doctors better understand what’s happening in the liver and improve future care.
Nashville, TennesseeAges 18–65 - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT00628199Enrolling by invitation
Skin sample study to create future cell therapies
This study collects skin cells from people with certain long-term conditions (or specific genetic disorders). Researchers use the cells to try to build new treatments for human disease and disability in the future.
Stanford, CaliforniaAges 1–75 - NCT01316783Enrolling by invitation
Genetics study of obesity, diabetes, and heart risk
This study looks at genetic differences in adults from African diaspora groups to better understand risks for obesity, type 2 diabetes, and heart disease. You may help scientists learn why these conditions are more common in certain communities.
Bethesda, MarylandAges 18–120 - NCT01171872Enrolling by invitation
Study blood and tissue gene signals in bowel inflammation
This study looks at gene activity (what your body’s genes are “doing”) in people with bowel inflammation during endoscopy or bowel surgery. It may help researchers understand inflammatory bowel disease and improve future diagnosis or treatments.
Baltimore, MarylandAges 7 years+ - NCT01460264Enrolling by invitation
A heart-and-lung health study following adults over time
This study follows adults with heart-and-lung health information over time to understand how these conditions change. It may help researchers find patterns that could guide better care in the future.
LundAges 45–75 - NCT02040714Enrolling by invitation
Study of current treatments for Perthes hip disease
This study follows children (and teens) with Legg-Calvé-Perthes disease to learn about how today’s treatments work in real life. It may help doctors choose the best next steps for your child’s hip health.
Birmingham, AlabamaAges 1–18 - NCT00047996Enrolling by invitation
Blood Donation Study for Blood Vessel Research
This study collects blood and urine samples from adults to help researchers understand diseases affecting blood vessels. Your donation helps scientists develop better treatments.
Bethesda, MarylandAges 18–100 - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07398287RecruitingPhase 2
Menthol for breathlessness in interstitial lung disease
This study tests if inhaling L-menthol can help reduce breathlessness in people with interstitial lung disease. You will cycle while breathing menthol or a placebo to see if it makes breathing easier.
Karlskrona, Blekinge CountyAges 18 years+ - NCT07399704RecruitingPhase 2
Testing a new drug for two rare brain diseases
This trial is for people with Niemann-Pick type C or GM2 gangliosidosis who are already on or have been in a related study. It tests a new drug called Nizubaglustat to see if it is safe and works better than current treatments.
Água Verde, CuritibaAges 12 years+ - NCT07400757Recruiting
Statin and vitamin D for active thyroid eye disease
This trial tests whether a statin (a cholesterol-lowering medicine) combined with vitamin D can improve active thyroid eye disease. It may help if you have both eye inflammation and high cholesterol.
Taipei, TaiwanAges 20 years+ - NCT07403539Recruiting
Speech learning and production in Parkinson's disease
This study looks at how people with Parkinson's disease learn and produce speech. It may help researchers understand how Parkinson's affects talking and how to improve communication.
Buffalo, New YorkAges 45 years+ - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07404644Recruiting
Study of vonicog alfa in children with von Willebrand disease
This study looks at how well vonicog alfa (a lab-made version of a missing blood protein) works to control bleeding in children under 18 with von Willebrand disease. It follows children who are already prescribed this treatment in Japan to see how safe and effective it is in real life.
Tokyo, TokyoAges Up to 17 years - NCT07405216RecruitingPhase 4
SGLT2 inhibitors for teens with early kidney disease
This trial tests whether a type of medicine called SGLT2 inhibitors can help teenagers with early-stage chronic kidney disease. It looks at how safe and effective these drugs are for slowing down kidney damage.
Aguascalientes, AguascalientesAges 14–18 - NCT07406867Recruiting
Can photos and bitewings detect gum disease?
This study tests whether photos, X-rays, and other non-invasive methods can identify gum disease as accurately as a clinical exam. It may help patients avoid needles or probing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07406932Recruiting
JAK inhibitors vs standard therapy for lung scarring in Anti-Synthetase Syndrome
This trial tests whether a new class of drugs called JAK inhibitors (which block inflammation signals) is better than a standard treatment (calcineurin inhibitors) for people with lung scarring (interstitial lung disease) caused by Anti-Synthetase Syndrome. It is for people who have not yet taken any immune-suppressing medications for this condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT07408336RecruitingEarly Phase 1
Study of AFN50 injection for active lupus
This study tests an investigational injection called AFN50 for people whose lupus (SLE) remains active despite standard treatments. The goal is to see if the drug can safely help control lupus symptoms better than current therapies alone.
Hefei, AnhuiAges 18–69 - NCT07409207Recruiting
Brain signals and reward in Parkinson's surgery
This study looks at brain activity related to reward during deep brain stimulation (DBS) surgery to help us understand Parkinson's disease better. If you are having DBS surgery, your brain signals during the procedure may help researchers.
Nashville, TennesseeAges 40 years+ - NCT07409519Recruiting
Nutrition Screening for Heart Disease Patients
This trial looks at how nutrition affects people with heart and blood vessel conditions. Anyone with cardiovascular disease can join—there are no strict medical rules.
Hull, E. Riding YorkshireAges 40–85 - NCT07415018Recruiting
Better MRI contrast for detecting cancer spread to brain lining
This study is testing different ways to give MRI contrast dye to better see if cancer has spread to the lining of the brain (leptomeningeal disease). It's for people with solid tumors who have had unclear results on standard scans or who are at high risk but have negative tests.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.