Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04806282Recruiting
Study to track hearing instability and find helpful targets
This study follows adults with hearing instability to better understand what causes it, measure it in new ways, and look for potential treatment targets. If you qualify, you may get hearing and balance-related testing (including scans) over a period of time.
Bethesda, MarylandAges 18–80 - NCT03276923Recruiting
Pregnancy registry for women with autoimmune disease
This study is a pregnancy and health registry for women with autoimmune (immune system) conditions who are trying to become pregnant or are already pregnant. It helps researchers better understand pregnancy outcomes and health needs in autoimmune disease.
Durham, North CarolinaAges Any age - NCT03329274Recruiting
Histiocytosis patient registry for Erdheim-Chester and related diseases
This is a registry (a research database) for people with Erdheim-Chester disease and other related “histiocytosis” conditions. It collects past and future medical information to better understand these illnesses and support future research.
New York, New YorkAges 18 years+ - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT04850053Recruiting
Using brain-related “seeds” to help diagnose Alzheimer’s disease
This study looks for specific markers (“seeds”) that may help doctors diagnose Alzheimer’s disease and distinguish it from other memory or thinking conditions. If you are in the right age range and can complete memory testing and provide a sample, you may help validate a diagnostic approach.
Beijing, Beijing MunicipalityAges 55–75 - NCT04848740Enrolling by invitation
Tested implant for worsening thin corneas
This trial looks at whether placing a donor-like cornea “lenticule” implant can help people whose cornea is getting worse, becoming thin, and causing blurry or reduced vision. The goal is to see if the implant can improve corneal clarity and vision in progressive disease.
PristinaAges 20–60 - NCT04784364Recruiting
Study of immune treatments at Mount Sinai
This study follows people who are receiving immune-related medications (called biologics or immune modulators) at Mount Sinai. It aims to better understand how these treatments affect the immune system and health over time, which may help improve future care.
New York, New YorkAges 12 years+ - NCT04843371Recruiting
Using wearable data to predict heart pump strength
This trial tests whether a wearable device (Biostrap) can help predict how strongly your heart pumps, using echocardiogram (heart ultrasound) results. It may help doctors better estimate heart function from simpler measurements.
New Orleans, LouisianaAges 18–120 - NCT04848844Recruiting
Congenital heart disease transplant registry study for adults
This study collects and shares anonymous information about adults being considered for a heart transplant because of a congenital (from birth) heart problem or an inherited heart muscle condition. The goal is to better understand these patients and support research that may improve care.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04799470Recruiting
Testing new brain-stimulation patterns for Parkinson’s with DBS
This study tests whether different deep brain stimulation settings can improve symptoms in people with Parkinson’s who already have an implanted DBS system in the subthalamic nucleus (STN). To join, you must already have the specific Medtronic device and show good brain signal and symptom response after surgery.
Omaha, NebraskaAges 19–80 - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
New Haven, ConnecticutAges 18 years+ - NCT04804202Recruiting
Virtual cycling program for people with Parkinson disease
This study tests whether a virtual, guided stationary bike exercise program is safe and helpful for people with Parkinson disease. It may help improve movement and fitness by letting you ride at home or in a controlled setting while using visual and audio guidance.
Newark, New JerseyAges 45–75 - NCT04800276Recruiting
Exercise program for leg artery disease
This trial tests a supervised exercise program for people with leg pain when walking caused by narrowed leg arteries. The goal is to see if exercise can improve walking ability and quality of life.
Le MansAges 18 years+ - NCT04806347RecruitingPhase 1
Stem cell transplant using a half-matched donor for children and young adults
This trial studies a type of stem cell transplant (bone marrow transplant) that uses a donor who is only half-matched to the patient, often a parent or sibling. It is for children and young adults with certain blood diseases, including sickle cell disease, thalassemia, bone marrow failure, and immune disorders. The transplant aims to replace the diseased blood-forming cells with healthy ones from the donor.
Madison, WisconsinAges 3 months–25 years - NCT04849806Recruiting
Testing whether heart nerve signals predict COPD symptoms
This study looks at “sympathetic nerve activity” (signals from the nervous system that affect the heart) in adults with chronic obstructive pulmonary disease (COPD). The goal is to see whether these measurements can help predict what happens to people with COPD.
AachenAges 18 years+ - NCT04848090Enrolling by invitation
Genetic testing for newborns in the hospital intensive care unit
This study uses whole-genome sequencing (a DNA test that looks across the genome) for newborns in the intensive care unit when doctors suspect a genetic condition. It aims to help identify possible genetic causes of illness and improve understanding for families and clinicians.
Pittsburgh, PennsylvaniaAges Up to 1 year - NCT04833907Enrolling by invitationPhase 1/Phase 2
Gene therapy study for typical Canavan disease in children
This early-phase trial tests a gene therapy medicine (delivered by a one-time infusion) for children with typical Canavan disease. It aims to improve safety and help evaluate whether the treatment may benefit children over time.
Dayton, OhioAges 3 months–5 years - NCT04779320RecruitingPhase 3
Vedolizumab for teens with moderate to severe Crohn's
This trial tests vedolizumab to treat children and teens with moderate to severe Crohn’s disease when standard treatments haven’t worked or caused side effects. It may help reduce gut inflammation and symptoms and help some patients stay healthier over time.
Phoenix, ArizonaAges 2–17 - NCT04819841RecruitingPhase 1/Phase 2
Gene correction using your own stem cells to improve sickle disease
This trial tests a gene-correction treatment that changes sickle hemoglobin (HbS) into normal hemoglobin (HbA) using your own stem cells. It may help reduce severe sickle cell complications for people with severe disease who meet specific safety and medical criteria.
Los Angeles, CaliforniaAges 12–50 - NCT04802395Recruiting
KidneyIntelX check for people with diabetes and early kidney disease
This study looks at how well a kidney test tool called KidneyIntelX works in real-world care for people with type 2 diabetes and certain stages of kidney disease. It may help doctors use the tool to better understand kidney risk and guide next steps.
New York, New YorkAges 23 years+ - NCT01245179RecruitingPhase 1
Panobinostat for adults with severe sickle cell
This early-phase study tests panobinostat, a medicine aimed at reducing sickle-cell problems, in adults with severe disease. It’s mainly looking at safety and whether it can improve blood-related issues that drive pain and complications.
Augusta, GeorgiaAges 18 years+ - NCT03671889Recruiting
Ultrasound treatment to open the brain barrier for Alzheimer’s
This trial tests a non-surgical ultrasound procedure (called MR-guided focused ultrasound) meant to temporarily “open” the brain’s protective barrier so treatments may work better for Alzheimer’s disease. It also looks at safety and how well people tolerate the procedure and related tests.
Delray Beach, FloridaAges 50–85 - NCT04715568RecruitingPhase 4
Testing how smoke exposure affects heart health
This study looks at whether being exposed to secondhand tobacco smoke at work affects heart and blood vessel health. It may help researchers understand which people are at higher risk and how the body responds to that exposure.
San Francisco, CaliforniaAges 40 years+ - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,374 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.