Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05584397Enrolling by invitation
Compare immune activity and HIV hidden reservoir on two treatments
This study compares how active the immune system is and how large the “hidden” HIV reservoir is in people on two different HIV treatment types. It may help researchers understand whether staying on a tenofovir-containing regimen leads to better control of HIV hiding in the body.
Seattle, WashingtonAges 18–65 - NCT05589714Recruiting
Study your rare eye gene and track retinal disease over time
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
Little Rock, ArkansasAges 4 years+ - NCT05582837RecruitingPhase 4
Using migraine medicines to treat Meniere’s disease symptoms
This Phase 4 study tests whether migraine-type medications can help people with active or frequent Meniere’s disease. If you have symptoms like inner-ear episodes, the trial may help find a better way to control them.
Orange, CaliforniaAges 25–85 - NCT05570994Enrolling by invitationPhase 1/Phase 2
PSMA-targeted radioactive drug for advanced prostate cancer
This Phase 1/2 study tests a radioactive treatment that targets PSMA, a protein often found on prostate cancer cells. It’s for men whose prostate cancer has worsened despite hormone-blocking pills like abiraterone or enzalutamide, aiming to help shrink or control the disease.
Vancouver, British ColumbiaAges 18 years+ - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05588063Recruiting
Device-based nerve stimulation for relapse-preventing kidney disease in kids
This trial tests whether a small non-surgical device can help keep children with steroid-sensitive nephrotic syndrome in remission. If it works, it could lower the chance of relapse (kidney flare-ups) and help maintain kidney health.
New Hyde Park, New YorkAges 3–17 - NCT05558605Recruiting
AI ultrasound guidance for heart risk management
This trial tests whether using an artificial-intelligence (AI) tool during a heart ultrasound can help guide care for people at risk for heart problems. You might benefit if you have symptoms with exercise or heart risk factors, but you do not already have known heart failure or major heart disease.
Alice Springs, Northern TerritoryAges 45 years+ - NCT05587049Recruiting
Testing an oral medicine plus azacitidine to improve AML disease
This study looks at how a standard AML treatment plan affects a person’s disease status over time. It focuses on newly diagnosed adults who cannot safely get intensive chemotherapy, using oral venetoclax plus azacitidine.
Medellín, AntioquiaAges 18 years+ - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05545306Recruiting
Study tests how extra calories change your daily energy use
This study looks at how eating more calories affects your body’s natural heat production and total energy use over a full day. It may help researchers better understand how the body manages weight and energy.
Phoenix, ArizonaAges 18–60 - NCT05514769Recruiting
Surgery type comparison for early-to-mid stomach cancer
This trial compares two different stomach cancer surgeries after removing the tumor, to see which works better for patients with stomach adenocarcinoma. It may help determine the safest approach and best recovery outcomes for people whose cancer has not spread.
Nanchong, SichuanAges 18–85 - NCT05548972Enrolling by invitation
Follow-up study of a hip replacement to improve implant wear
This study checks how well a specific hip replacement bearing surface (called dual mobility with Vivacit-E or Longevity) performs over time in real-world patients. It may help people by tracking long-term safety and performance to guide better hip replacement choices.
Little Rock, ArkansasAges 18–80 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05530408Recruiting
Pulmonary scan imaging registry and blood sample collection
This trial builds a research database from people who take lung scans like pulmonary MRI or CT at the University of Kansas Medical Center. It may help researchers better understand lung disease and improve future diagnosis or treatment.
Kansas City, KansasAges 18 years+ - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT05544968RecruitingPhase 1
CD30-targeted cell treatment for hard-to-treat blood cancers
This Phase 1 trial studies an experimental treatment that targets a marker called CD30 on cancer cells. It is for adults with certain relapsed or refractory CD30-positive blood cancers to see how well the treatment works and what side effects it causes.
Milwaukee, WisconsinAges 18 years+ - NCT05525312Recruiting
Two breathing strategies during lung surgery for lung cancer
This trial compares two ways of managing breathing while you have surgery to remove lung cancer. It may help doctors figure out which strategy is safer and works better during the operation.
MontpellierAges 18 years+ - NCT05533528Recruiting
Save gum tissue in surgery for severe periodontitis
This trial studies a way to preserve gum (periodontal) “granulation” tissue during surgical treatment for severe periodontitis (gum disease). It may help patients heal better after surgery, especially when deep gum pockets do not improve after non-surgical care.
MurciaAges 18 years+ - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70 - NCT05534321RecruitingPhase 1/Phase 2
Preventive radiation for high-risk spinal bone metastases
This trial tests whether preventive (before serious problems happen) radiation to the spine can help people with high-risk, mostly symptom-free bone metastases. It may reduce the chance of pain escalation or dangerous complications from cancer in the spine.
Miami, FloridaAges 18 years+ - NCT05545865Recruiting
Test how grape-based drinks affect blood flow response
This study tests whether a grape product (“Chardonnay Marc”) can change how your blood vessels respond to stress, measured with a finger sensor. It may help researchers understand how diet influences circulation in people with a low baseline blood-flow response.
Davis, CaliforniaAges 30–50 - NCT05521503Recruiting
Collecting heart tissue samples for a shared research database
This trial builds a database by collecting and storing biopsy or biopsy-related samples from adults being evaluated for certain heart conditions. It may help researchers study heart disease and amyloidosis by making past tissue samples easier to access for future research.
Lexington, KentuckyAges 18 years+ - NCT05528744Recruiting
Study genes and symptoms in ANKRD17-related CAGS
This study looks at how a specific gene change in ANKRD17 relates to the symptoms, brain/scan findings, and brain-cells in people with Chopra-Amiel-Gordon syndrome (CAGS). It may help families understand the condition better and connect gene results to what is seen clinically.
Boston, MassachusettsAges Any age
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,350 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.