Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02422641RecruitingPhase 2
High-dose methotrexate for breast cancer in the brain lining
This Phase 2 trial tests whether giving high-dose methotrexate into the bloodstream can help treat breast cancer that has spread to the thin lining covering the brain and spinal cord. It may help reduce cancer in the leptomeningeal (brain-lining) area and control symptoms.
Baltimore, MarylandAges 18 years+ - NCT02454569Recruiting
Study for people living with HIV willing to join
This study follows people who have tested positive for HIV. It aims to better understand HIV over time, but you can only participate if you agree to join the study.
Battalapalli, Andhra PradeshAges Any age - NCT02918188RecruitingPhase 2
Hydrogen therapy for steroid-resistant graft-versus-host disease
This Phase 2 study tests whether hydrogen therapy can improve symptoms in people with chronic graft-versus-host disease (cGVHD) who cannot tolerate steroid treatment. If steroids aren’t working or can’t be used, this trial may offer an alternative approach to help control the illness.
Beijing, Beijing MunicipalityAges Up to 65 years - NCT02823821RecruitingPhase 4
Testing different salt levels in dialysis fluid to prevent blood vessel events
This study tests whether changing the salt (sodium) level in dialysis fluid can reduce problems in blood vessels. It is done in adult dialysis centers to compare outcomes between two sodium levels.
AdelaideAges 18 years+ - NCT02485847Recruiting
Join an eye health research registry
This trial is a research registry that collects information from people who are getting eye care. It helps researchers better understand eye disease and outcomes over time, which may improve future care.
San Francisco, CaliforniaAges 6 months+ - NCT02550236Recruiting
LIFE Child study for children and pregnancy in Leipzig
This research study enrolls children with their families and pregnant women living in the Leipzig area. It is intended to improve understanding of health factors in childhood and pregnancy.
Leipzig, SaxonyAges birth–20 years - NCT02541435Recruiting
Breast cancer radiotherapy side effects study
This study looks at heart and blood-vessel side effects after modern radiation treatment for breast cancer, both soon after and years later. It may help doctors understand who is at risk and how to monitor heart health over time.
ÅlesundAges 30–70 - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT02579967RecruitingPhase 2
Stem cell transplant for primary immune system disorders
This study tests whether an allogeneic stem cell (bone marrow) transplant can correct an inherited immune problem in people with severe primary immunodeficiencies. It may help reduce life-threatening infections and improve quality of life, depending on your overall health and donor match.
Bethesda, MarylandAges 4–75 - NCT02614911Recruiting
Genetics and health profile study for early severe bowel disease
This study looks at how an early-onset bowel illness looks and what genetic changes may be involved. It may help researchers better understand inherited causes and improve future care for families affected by these conditions.
BordeauxAges Any age - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT02685969Recruiting
Brain scan study of amyloid and brain sugar use
This study uses brain imaging to measure two things in the brain—amyloid protein and how the brain uses sugar. It may help researchers better understand early brain changes in people in the ALFA project.
Barcelona, CataloniaAges 45–75 - NCT02763683Recruiting
Study brain changes in Parkinson-related dementia
This study looks at brain features linked to dementia in people who have Parkinson disease. It may help researchers understand why dementia happens in Parkinson and how it could be detected or treated in the future.
St Louis, MissouriAges 50 years+ - NCT02777879Recruiting
Study gut-like lung bacteria and inflammation in early COPD
This study looks at the lung’s tiny bacteria (microbiome) and inflammation in people with early COPD who have a smoking history. It compares them with smokers who have normal breathing tests, to better understand what may drive COPD early on.
New York, New YorkAges 18–70 - NCT02850588Recruiting
Track outcomes after carotid stent or surgery
This study follows people who need a procedure to treat narrowed carotid arteries, comparing results after either surgery (CEA) or a less invasive procedure (TCAR). It mainly looks at patient safety and outcomes, which can help improve future care.
Chicago, IllinoisAges 18 years+ - NCT02892877Recruiting
Study for certain pregnancy-related tumor conditions
This study is for people who have a pregnancy-related tumor called gestational trophoblastic disease. It looks at this condition in patients who were diagnosed by blood test (hCG) changes or tissue testing, to better understand and manage the disease.
Pierre-BéniteAges Any age - NCT02917460Recruiting
Join a children’s genomic sample and data library
This study collects and stores DNA samples and related health information from people of all ages. It helps researchers understand childhood diseases better and may support future discoveries and treatments.
San Diego, CaliforniaAges Any age - NCT02986516Recruiting
Surgery or definitive radiation for primary sacral chordoma
This trial compares two standard treatment approaches—surgery versus definitive radiation—for people with a primary sacral chordoma (a bone tumor at the lower spine/pelvis area). It aims to find which approach works best for controlling the tumor while considering treatment side effects.
GrazAges 18–80 - NCT03049462RecruitingPhase 1
Study how a beta-3 drug changes body fat in healthy adults
This Phase 1 study tests how chronic treatment with a beta-3–type medicine affects brown fat (a special kind of body fat) in the body. It mainly looks at safety and how the body responds over time, which could help future treatments for weight and metabolic health.
Bethesda, MarylandAges 18–40 - NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT03358979Recruiting
3D eye-surface testing for severe dry eye
This study looks at how a specific eye-surface marker (EMMPRIN) changes on the surface cells in people with severe dry eye. It may help researchers understand disease severity and how new treatments could work for severe symptoms.
ParisAges 18 years+ - NCT03209583Recruiting
Test of fast-pacing therapy for congenital heart rhythm issues
This trial studies whether a device-based fast pacing therapy (called ATP) can better treat certain rapid heart rhythm problems in people born with a heart condition. It may help prevent or reduce episodes of atrial (upper-chamber) arrhythmias that occur despite having a pacing/defibrillator device.
Los Angeles, CaliforniaAges Any age - NCT03358693Recruiting
Study of inflammation patterns in chronic skin diseases
This study looks at molecular (body-level) signatures in people with chronic inflammatory skin conditions. You may help researchers understand what drives inflammation, while receiving standard (already approved) systemic treatment through routine care.
KielAges Any age - NCT02945345Recruiting
Test how skin scores change in cutaneous dermatomyositis
This study looks at how well skin symptoms improve in adults with cutaneous dermatomyositis by using a specific skin-scoring tool. The results may help doctors better measure treatment response and guide care.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.