Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07721701Recruiting
Digital Dementia Registry for Bavaria
This study follows people with mild cognitive impairment or dementia and their family caregivers over time. It aims to learn more about how these conditions progress and how to improve care, especially for those living in Bavaria.
AschaffenburgAges Any age - NCT06506942Recruiting
TRICURE device study for leaky heart valve
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT07616154RecruitingPhase 2
Gene-Matched Family Stem Cell Transplant for Severe Sickle Cell
This trial tests whether a stem cell transplant from a partially gene-matched family member can cure severe sickle cell disease in children and young adults. The transplant uses a new approach that may work even when a perfectly matched sibling isn't available, and it might help patients whose sickle cell is causing serious complications like strokes, organ damage, or frequent pain crises.
Memphis, TennesseeAges Up to 22 years - NCT07245706Recruiting
Shoulder Health After Rehab and Performance Training
This study looks at how shoulder health changes after a rehabilitation and performance training program for people with paraplegia who use manual wheelchairs. It may help you strengthen your shoulders and prevent injuries as you start your life after rehab.
Nottwil, Canton of LucerneAges 18–70 - NCT07537075Enrolling by invitationPhase 2/Phase 3
Continuing SKY-0515 treatment for Huntington's disease
This is a follow-up study for people with Huntington's disease who already completed an earlier SKY-0515 trial and tolerated it well. Researchers want to see how safe and effective the drug continues to be with longer-term use.
New Lambton Heights, New South WalesAges 25 years+ - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT06188793Recruiting
Virtual reality for IBD pain during hospital stay
This study tests if using virtual reality can help manage pain for people with inflammatory bowel disease (IBD) while they are in the hospital. It may offer a drug-free way to feel better.
Ann Arbor, MichiganAges 18 years+ - NCT06810622Recruiting
NAVIGATE Kidney: Reducing Kidney Health Disparities
This study is testing a program called NAVIGATE Kidney that aims to improve kidney health and reduce racial or ethnic gaps in care. It is for adults with advanced kidney disease (eGFR 15-29) who are not yet on dialysis or had a transplant, and it involves education and support to help manage their condition.
Denver, ColoradoAges 18–75 - NCT07288554RecruitingPhase 1
Study of BBT002 for healthy people and COPD patients
This trial tests an experimental drug called BBT002 in healthy volunteers and people with chronic obstructive pulmonary disease (COPD), a lung condition that makes breathing hard. It aims to see if the drug is safe and how the body processes it.
Hefei, AnhuiAges 18–75 - NCT07710625Recruiting
Heat sensitivity scale for Parkinson's disease
This study is testing a new questionnaire to measure how heat affects people with Parkinson's disease. If you have Parkinson's and notice changes with heat, this may help doctors better understand your symptoms.
Istanbul, TurkeyAges 40–85 - NCT06214507Recruiting
Danon disease natural history study
This study follows people with Danon disease over time to better understand how the condition progresses. It may help guide future treatments.
Phoenix, ArizonaAges 8 years+ - NCT07512687Recruiting
Portable Oxygen During Daily Activity for Lung Disease
This study tests whether using portable oxygen during everyday activities helps people with certain lung diseases (like pulmonary fibrosis or COPD) who only experience low oxygen levels when moving around. Researchers want to see if a portable oxygen device improves how well participants can function and feel during daily life.
Buffalo, New YorkAges 18–85 - NCT07704567Recruiting
Using MoblO2 to maintain oxygen levels during activity
This study tests a device called MoblO2 to help people with COPD or interstitial lung disease keep their oxygen levels up during activity. If you normally use oxygen when you walk or exert yourself, this might help you stay active more safely.
Denver, ColoradoAges 25–95 - NCT04925375RecruitingPhase 2
Abatacept for children with CVID and lung scarring
This Phase 2 trial tests abatacept to improve a specific type of lung disease in children with common variable immunodeficiency (CVID). It aims to slow or reduce ongoing lung changes seen on CT scans while they continue their usual immune “replacement” therapy.
San Francisco, CaliforniaAges 4 years+ - NCT03549754Recruiting
iCaReMe registry for adults with diabetes, blood pressure, or heart/kidney disease
This is a health “registry,” meaning it collects information about people living with common chronic conditions. It may help researchers better understand real-world health needs and outcomes for people with type 2 diabetes, high blood pressure, heart failure, and/or chronic kidney disease.
Fortaleza, CearáAges 18 years+ - NCT04799470Recruiting
Testing new brain-stimulation patterns for Parkinson’s with DBS
This study tests whether different deep brain stimulation settings can improve symptoms in people with Parkinson’s who already have an implanted DBS system in the subthalamic nucleus (STN). To join, you must already have the specific Medtronic device and show good brain signal and symptom response after surgery.
Omaha, NebraskaAges 19–80 - NCT04877197Recruiting
Home telehealth coaching to improve mood after heart hospitalization
This Phase 3 study tests a home-based telehealth program (behavioral activation coaching) to improve functioning in people who recently left the hospital after a heart-related event and also have major depression. It may help you feel more able to do everyday activities and better manage depression symptoms.
Charleston, South CarolinaAges 21 years+ - NCT05266417RecruitingPhase 2
Nasal insulin plus glutathione for Parkinson’s symptoms
This Phase 2 study tests whether adding nasal insulin and glutathione can improve Parkinson’s disease symptoms and function. You would use study medicine through the nose while keeping your other treatments mostly the same during the trial.
Davie, FloridaAges 30 years+ - NCT07718334Recruiting
Can a medication reminder app improve sticking to treatment?
This study tests whether a mobile app that reminds you to take your medicine can help people who have both chronic health conditions and memory problems stick to their treatment plan. A nurse leader will help guide the program, and you or a caregiver will use the app on a smartphone.
Gamasa, Dakahlia GovernorateAges 18 years+ - NCT07716397Recruiting
MRI study for thyroid eye disease diagnosis and care
This study uses MRI scans of the eye area to better understand and classify thyroid eye disease (TED). It aims to help doctors predict outcomes and personalize treatment. You may be eligible if you have stable TED or are a healthy volunteer.
Shanghai, Huangpu DistrictAges 18–75 - NCT05680012Recruiting
Testing how gluten affects healing in celiac disease
This study looks at how the gut lining “tissues” are affected during gluten eating versus avoiding gluten in people with celiac disease. It may help researchers understand what drives healing and tissue damage in celiac disease.
Pasadena, CaliforniaAges 18–75 - NCT06967389Recruiting
Helping kids with severe obesity reduce heart risks
This trial tests whether semaglutide can lower heart disease risks in children with extreme obesity. It aims to improve weight and heart health over time.
Lexington, KentuckyAges 12–17 - NCT07710157RecruitingPhase 2
Obinutuzumab for first episode of minimal change disease
This trial tests if obinutuzumab, a targeted therapy, can safely and effectively treat adults with their first episode of minimal change disease (MCD), a kidney condition causing protein leakage. Participants will receive the drug to see if it reduces protein in urine and improves symptoms.
GrazAges 18 years+ - NCT06653413Recruiting
Using dynamic chest x-ray to diagnose COPD
This study tests if a new type of chest x-ray (dynamic chest x-ray) can help diagnose COPD. You would breathe normally and deeply while the x-ray takes images for 20 seconds. This could be a more comfortable way to check for COPD compared to standard breathing tests.
Guangzhou, GuangdongAges 40–80
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.