Clinical trials · Colorado
Down Syndrome clinical trials in Colorado
We’re tracking 99 recruiting down syndrome studies with a site in Colorado — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Colorado
- NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Aurora, ColoradoAges birth–20 years - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Aurora, ColoradoAges Any age - NCT05052606Recruiting
Turner syndrome patient registry study
This is a registry study that collects health information from people who have Turner syndrome. It helps researchers better understand the condition and guide future care.
Aurora, ColoradoAges Any age - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Denver, ColoradoAges 18 years+ - NCT05127226RecruitingPhase 1/Phase 2
Test drug safety for Angelman syndrome in young children
This early-phase study tests a new experimental medicine called ION582 to see if it is safe, tolerable, and how the body processes it in people with Angelman syndrome. It may also look at early signs of how the medicine affects the brain and body, which could guide future treatments.
Aurora, ColoradoAges birth–50 years - NCT05410977Recruiting
Testing blood and stool for colon cancer in Lynch syndrome
This study collects blood and stool samples to see how well they can detect colorectal cancer or advanced growths in people with Lynch syndrome (an inherited colon cancer risk) or suspected Lynch syndrome. It may help find cancer or precancer earlier, which can improve next-step decisions.
Aurora, ColoradoAges 18 years+ - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT06247787RecruitingPhase 1
Imetelstat plus chemo for relapsed leukemia in kids
This trial tests a new drug called imetelstat combined with two chemotherapy drugs (fludarabine and cytarabine) for children and teens with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or juvenile myelomonocytic leukemia (JMML) that has come back or not responded to treatment. The goal is to find the safest dose of imetelstat and see if it helps control the cancer.
Aurora, ColoradoAges 1–18 - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Aurora, ColoradoAges 6 years+ - NCT06430385RecruitingPhase 1/Phase 2
Study of ION440 for MECP2 Duplication Syndrome
This trial tests an experimental medicine called ION440 for people with MECP2 Duplication Syndrome. The medicine is given as an injection into the spinal fluid, and the study aims to check its safety and how well it works.
Aurora, ColoradoAges 2–65 - NCT05419492RecruitingPhase 1/Phase 2
ETX101 for children with SCN1A Dravet syndrome
This early-phase study tests how safe ETX101 is and whether it can help reduce seizures in young children with Dravet syndrome caused by an SCN1A gene change. It mainly enrolls infants and children with a specific type of seizure history and genetic result.
Aurora, ColoradoAges 6 months–17 years - NCT06582914Recruiting
Lynch syndrome genetics and health study
This study looks at the genetics and health of people with Lynch syndrome, a condition that raises the risk for certain cancers. Researchers want to learn more about how different genetic changes affect health over time.
Aurora, ColoradoAges 18 years+ - NCT06598449RecruitingPhase 4
Safety of fenfluramine in children under 2 with Dravet syndrome
This trial tests the safety of a medicine called fenfluramine for children under 2 years old with Dravet syndrome. It aims to see if fenfluramine can help control seizures in very young children.
Aurora, ColoradoAges 1–2 - NCT06668805RecruitingPhase 2
Testing vosoritide for children with Noonan syndrome and slow growth
This study tests a medication called vosoritide for children with Noonan syndrome who are still growing slowly despite using human growth hormone. The goal is to see if vosoritide can help them grow taller.
Aurora, ColoradoAges 3–11 - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Denver, ColoradoAges birth–21 years - NCT06716411Recruiting
Acupuncture for Gulf War Illness relief
This study tests whether acupuncture can help relieve Gulf War Illness symptoms like fatigue, mood or thinking problems, and muscle or joint pain. You may be able to join if you were deployed to the Gulf region and have had these symptoms for more than 6 months.
Colorado Springs, ColoradoAges 18 years+ - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Fort Collins, ColoradoAges 18 years+ - NCT06840496RecruitingPhase 3
Study of oral NA-921 vs placebo for girls and women with Rett syndrome
This trial tests an oral medication called NA-921 in females with Rett syndrome to see if it works better than a placebo. It may be an option for those who have a confirmed MECP2 gene mutation and stable seizure patterns.
Aurora, ColoradoAges 5–20 - NCT07020819RecruitingPhase 3
Study of tanruprubart for people with Guillain-Barré syndrome
This trial tests a new medicine, tanruprubart (also called ANX005), for people with Guillain-Barré syndrome. It aims to see if the drug can help improve recovery when given soon after symptoms start.
Aurora, ColoradoAges 12–85 - NCT07209462RecruitingPhase 2
MRM-3379 for Fragile X Syndrome in males
This trial tests an investigational medicine called MRM-3379 in males with Fragile X syndrome. It looks at how the medicine affects thinking and behavior over time.
Aurora, ColoradoAges 13–45 - NCT07238465RecruitingPhase 3
Exploring nervous system function in Down syndrome
This trial studies how the nervous system works in people with Down syndrome. It may help understand differences in body functions and improve future care.
Aurora, ColoradoAges 18–50 - NCT01522183Recruiting
Registry for people with atypical hemolytic uremic syndrome
This is a registry that collects information from people diagnosed with atypical hemolytic uremic syndrome (aHUS). It helps researchers better understand the condition across different genetic causes and treatment needs.
Aurora, ColoradoAges Any age - NCT01950624Recruiting
DS-Connect registry for people with Down syndrome
This is a study registry that collects information from people with Down syndrome (or certain forms like mosaic or partial trisomy 21) and their families. It helps researchers learn about health and needs over time and makes it easier to contact people for future studies.
Aurora, ColoradoAges Any age
Down Syndrome trials by city in Colorado
Where these studies are running in Colorado
Institutions with a site for the recruiting down syndrome studies listed above.
- Children's Hospital Colorado · 12 studies
- University of Colorado Anschutz Medical Campus · 4 studies
- Linda Crnic Institute for Down Syndrome · 2 studies
- UCHealth University of Colorado Hospital · 2 studies
- Biomed Testing Facility
- Clinical Trial Site
- Denver Health Medical Center
- Tekton Research
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Down Syndrome trials in other states
Common questions
- Are there down syndrome clinical trials in Colorado?
- Yes. We're currently tracking 99 recruiting down syndrome studies with a site in Colorado, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study in Colorado?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Colorado to take part?
- Not necessarily. These studies have a site in Colorado, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open in Colorado regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.