Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06622902Recruiting
How flow changes affect CO2 in preemies on high-flow breathing support
This study watches how changing the flow of air through a breathing device (high-flow nasal cannula) affects carbon dioxide levels in preemies. It helps doctors learn the safest way to adjust breathing support for fragile infants.
HaifaAges Any age - NCT06611228Recruiting
Preventing disability in older hospital patients
This study tests if a program designed for older, frail hospital patients can prevent loss of ability to do daily tasks. It focuses on physical activity, mental engagement, and nutrition to help you stay independent.
Monza, LumbardyAges 70 years+ - NCT06616363Recruiting
Brain and nerve connection in POTS and after infection
This study looks at why some people develop POTS (a condition that causes a fast heart rate and dizziness when standing) and if it's linked to how the brain and vagus nerve work together. It also includes people recovering from a serious infection and healthy volunteers for comparison.
Richmond, VirginiaAges 12–21 - NCT06615622Recruiting
Using ultrasound to detect nerve changes in GBS and CIDP
This study tests if ultrasound can find nerve problems in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP), and if it helps doctors diagnose and predict outcomes early.
AsyutAges 18–75 - NCT06613204Recruiting
Support program for family caregivers of FTD patients
This study tests a behavior change program for family members caring for someone with frontotemporal degeneration (FTD). It aims to help caregivers manage upsetting behaviors and reduce stress.
Portland, OregonAges 18–100 - NCT06601452Enrolling by invitationEarly Phase 1
Chinese medicine for anovulatory infertility in IVF
This trial tests a treatment for women with infertility caused by ovulation problems, like PCOS or low ovarian reserve, or when IVF is needed due to a male factor. It aims to see if a Chinese medicine approach can help improve IVF success.
Nanjing, JiangsuAges 20–41 - NCT03850574RecruitingPhase 1/Phase 2
Tuspetinib for relapsed or hard-to-treat AML
This early-phase study tests tuspetinib in people with AML that has come back or did not respond to treatment. The goal is to learn whether it is safe and tolerable, how the drug behaves in the body, and whether it shows signs of benefit.
Birmingham, AlabamaAges 18 years+ - NCT05431101Recruiting
Absorbable versus non-absorbable stitches after carpal tunnel surgery
This study compares two types of stitches used to close the skin after carpal tunnel release surgery. It may help show which stitch type leads to better healing and comfort afterward.
ApeldoornAges 18 years+ - NCT06594445RecruitingPhase 1
GTB-3650 TriKE for high-risk MDS and relapsed AML
This trial tests a new immunotherapy called GTB-3650 TriKE for people with high-risk MDS or AML that has come back or not responded to treatment. It aims to boost your immune system to fight the cancer.
Minneapolis, MinnesotaAges 18 years+ - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT06585605Recruiting
Study of epilepsy and movement disorder genes in children
This study looks at children with epilepsy and movement disorders to better understand the genes involved. It aims to help doctors recognize and treat these conditions more effectively.
Boston, MassachusettsAges birth–18 years - NCT06588868Recruiting
Systemic treatments for cutaneous T-cell lymphoma
This trial looks at the results of different systemic (whole-body) treatments for cutaneous T-cell lymphoma (CTCL), a rare type of lymphoma that affects the skin. It aims to understand how well these therapies work and help guide future treatment choices.
AnconaAges 18 years+ - NCT06388174Recruiting
Idiopathic Generalized Epilepsy Study
This study is looking at people with a specific type of epilepsy called idiopathic generalized epilepsy (IGE). The goal is to collect health information and use a 24-hour brain wave test to learn more about the condition.
Hangzhou, ZhejiangAges 4–40 - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+ - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06576323Recruiting
Support for mothers with opioid use disorder and babies in the NICU
This study aims to improve care for mothers with opioid use disorder and their babies with neonatal abstinence syndrome. Researchers will interview healthcare providers and mothers to develop better support programs.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06576726Recruiting
Tracking tic disorder in teens over time
This study follows teens with chronic tic disorders (like Tourette syndrome) for a few years to understand how their symptoms and social life change. It also looks at brain signals using EEG, but you can join the main study even if you can't do the EEG part.
Nashvile, TennesseeAges 11–17 - NCT05737342Recruiting
Test supplement to lower A1c and steady blood sugar
This trial studies ANKASCIN 568-P products to see if they can lower A1c (a blood sugar average) and help regulate blood glucose. It may help people with early blood sugar problems, but you must avoid diabetes medicines during the study.
TaipeiAges 20 years+ - NCT06553898RecruitingPhase 1
CAR-T cell therapy for hard-to-treat kidney disease
This trial tests a new CAR-T cell treatment for children and adults with steroid-resistant nephrotic syndrome (SRNS), a kidney condition that doesn't get better with standard medicines. The goal is to see if this therapy can help improve kidney function when other treatments have failed.
Hangzhou, ZhejiangAges 2 years+ - NCT06566625Recruiting
MRI before heart catheterization for heart attack
This trial compares using a cardiac MRI before the standard catheterization (angiogram) in people with a suspected heart attack that doesn't show the typical ECG changes. It aims to see if the MRI can help guide decisions and avoid unnecessary procedures.
Stockholm, SwedenAges 18 years+ - NCT06560242Recruiting
Tracking early sound perception in Fragile X syndrome
This study uses safe brain monitoring (fNIRS and EEG) to see how infants with Fragile X syndrome process sounds compared to other infants. The goal is to find early signs of hearing or perception issues.
Cincinnati, OhioAges 6 months–2.2 years - NCT06566664Enrolling by invitation
Peripheral neurostimulation for improving nerve block placement in upper limb surgery
This study looks at using peripheral neurostimulation to improve the placement of nerve blocks for upper limb surgery. It may help you get better pain control during and after your operation.
Stanford, CaliforniaAges 18 years+ - NCT06551584RecruitingPhase 1
Advanced blood cancer trial with stem cell transplant
This trial tests a new approach for people with advanced blood cancers who are getting a donor stem cell transplant. It aims to improve outcomes by using your own regulatory T cells along with the donor cells.
Palo Alto, CaliforniaAges 18–70 - NCT06566742RecruitingPhase 2
Olutasidenib for IDH1-mutated blood disorders
This trial tests an oral drug called olutasidenib in people with certain low-risk blood cancers or a pre-cancer condition. It may help by targeting a specific genetic change (IDH1 mutation) found in your blood cells.
Miami, FloridaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.