Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06652087Recruiting
Testing rifaximin for heart failure with preserved pumping
This trial tests whether the antibiotic rifaximin (taken by mouth) can improve heart function in people with a type of heart failure where the heart pumps well but is still weak (HFpEF). Rifaximin might help by changing the bacteria in your gut.
MoscowAges 18–80 - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT06653985Recruiting
Hip injection plus physical therapy for mild hip problems
This trial tests a combination of a steroid and lubricant injection into the hip joint plus physical therapy to treat mild hip arthritis or related issues like a labral tear. It aims to see if this approach can reduce pain and improve function without surgery.
Hamilton, OntarioAges 40–60 - NCT06657326Recruiting
New stent for high bleeding risk patients
This trial tests a new type of stent (BioFreedom Ultra) compared to a standard one (BioFreedom) in people who have a high risk of bleeding. Both stents release medicine to keep arteries open, and the study checks if the newer stent works better with a shorter course of blood thinners.
Johor Bahru, JohorAges 18 years+ - NCT06661278Recruiting
Exercise testing in kids with inherited heart rhythm conditions
This study looks at how children with certain genetic heart rhythm problems, like long QT syndrome, respond to exercise. It may help doctors understand how to better manage these conditions.
LondonAges 6–16 - NCT06661655Recruiting
Testing a new ultrasound for liver fat in MASLD patients
This study tests a new ultrasound device that uses sound waves to measure fat in the liver without needles or surgery. It is for people with a type of fatty liver disease called MASLD or MASH, who are already getting an MRI to check their liver.
AngersAges 18–80 - NCT06662630Recruiting
Oscillatory ventilation study for ICU patients on breathing machines
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06665867Recruiting
Video Follow-Up for Kids With Stomach Pain
This trial tests whether video consultations (video calls) are a good option for follow-up appointments in children with functional abdominal pain disorders. It aims to make check-ups easier for families.
AmsterdamAges 4–17 - NCT06666777Recruiting
Speech therapy and parenting for early communication skills
This study tests a program that combines speech therapy with parenting support to help young children with developmental delays improve their communication and social skills. It is designed for children aged 6 months to 5 years who have developmental challenges, and their parents.
Como, ComoAges 6 months–4.9 years - NCT06668714Recruiting
Does lactate affect nutrient absorption and fat storage?
This study tests whether taking lactate (a natural substance) with a meal affects how your body absorbs nutrients and stores fat. It is for people with prediabetes who are not on glucose-lowering medication.
AarhusAges 50 years+ - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT06669962Recruiting
Studying heart function in Takotsubo syndrome
This trial aims to understand the chemical and physical changes in the heart's blood vessels during Takotsubo syndrome, a temporary heart condition often triggered by stress. It may help doctors better diagnose and treat this condition.
Turin, TurinAges 18–90 - NCT06677580Recruiting
OSA digital network for early diagnosis and monitoring
This trial tests a digital tool to help diagnose and monitor obstructive sleep apnea earlier. It may help people with sleep apnea get better care.
Milan, ItalyAges 18 years+ - NCT06678737RecruitingPhase 2
TMS plus behavioral therapy for teens with tics
This study tests whether combining a brain stimulation technique called TMS with behavioral therapy can reduce tics in adolescents and young adults. If you have had tics for at least a year and they are moderate or severe, this trial may be a good fit.
Minneapolis, MinnesotaAges 12–21 - NCT06680752RecruitingPhase 1/Phase 2
A car-t cell therapy trial for AML or MDS
This trial tests a new CAR-T cell therapy, ARD103, for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has come back or is not responding to treatment. It aims to see if this therapy can help control the disease.
Charlotte, North CarolinaAges 18 years+ - NCT06682286Recruiting
Breathing patterns during nighttime NIV
This study looks at how people breathe while using their nighttime breathing machine (NIV). It helps doctors understand breathing patterns better for people with COPD or OHS.
AucklandAges 18 years+ - NCT06684119Recruiting
Testing best breathing tube pressure for children on a ventilator
This trial uses a special imaging tool (EIT) to find the best air pressure in the breathing tube for children on a ventilator. It aims to improve lung function in children with a lung condition called PARDS.
Los Angeles, CaliforniaAges birth–18 years - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06688214Recruiting
Kinesiology taping and shoulder exercises for shoulder pain
This trial tests if kinesiology taping (a special type of tape applied to the shoulder) plus exercises that strengthen the shoulder blades works better than just exercises alone for people with shoulder impingement syndrome (a common cause of shoulder pain). You may qualify if you have had pain on the front or side of your shoulder for at least 3 months and have certain positive tests from a physical therapist.
Lahore, Punjab ProvinceAges 18–55 - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+ - NCT06696287Recruiting
6-minute hand and arm test in fibromyalgia
This study tests a simple 6-minute hand and arm exercise (pegboard and ring test) in people with fibromyalgia. It helps researchers understand how well you can use your hands and arms during daily activities.
KırşehirAges 18–65 - NCT06696638Recruiting
Guiding breathing help with lung imaging vs. pressure in ARDS
This trial compares two ways to set the breathing machine for people with ARDS (a serious lung injury). One method uses a special imaging belt (EIT) to see how the lungs are working, while the other uses pressure measurements. The goal is to find the best way to adjust ventilator support to help you breathe more easily.
Wuhan, HubeiAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.