Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+ - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06686537RecruitingPhase 2
Study on metabolism and hormones in women
This study looks at how metabolism and hormones are connected in women. It tests a treatment to see if it can improve metabolic health related to the menstrual cycle.
Aurora, ColoradoAges 18–38 - NCT06691178Recruiting
Vaginal changes after CO2 laser therapy
This study looks at how CO2 laser therapy affects the vagina in people who have gone through menopause and have genitourinary symptoms like dryness or discomfort. It aims to understand the benefits and changes that happen after treatment.
Irvine, CaliforniaAges 18 years+ - NCT06680752RecruitingPhase 1/Phase 2
A car-t cell therapy trial for AML or MDS
This trial tests a new CAR-T cell therapy, ARD103, for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has come back or is not responding to treatment. It aims to see if this therapy can help control the disease.
Charlotte, North CarolinaAges 18 years+ - NCT06678737RecruitingPhase 2
TMS plus behavioral therapy for teens with tics
This study tests whether combining a brain stimulation technique called TMS with behavioral therapy can reduce tics in adolescents and young adults. If you have had tics for at least a year and they are moderate or severe, this trial may be a good fit.
Minneapolis, MinnesotaAges 12–21 - NCT06679972Enrolling by invitation
Impact of pregnancy liver condition on baby's breathing
This study looks at how a pregnancy liver condition (intrahepatic cholestasis) affects the baby's breathing after birth. It compares newborns whose mothers had this condition (and took medication for it) with newborns whose mothers did not have any liver issues during pregnancy.
Bucharest, BucharestAges 1 hour–4 weeks - NCT06678646Recruiting
Ultrasound-guided elbow nerve release for Lacertus syndrome
This trial tests a minimally invasive ultrasound-guided procedure to release the median nerve at the elbow in people with Lacertus syndrome (a condition where the nerve gets compressed). It aims to relieve symptoms like pain, tingling, or weakness in the hand and forearm.
Versailles, YvelinesAges 18–70 - NCT06661655Recruiting
Testing a new ultrasound for liver fat in MASLD patients
This study tests a new ultrasound device that uses sound waves to measure fat in the liver without needles or surgery. It is for people with a type of fatty liver disease called MASLD or MASH, who are already getting an MRI to check their liver.
AngersAges 18–80 - NCT06662188RecruitingPhase 1/Phase 2
Gene therapy for children with SHANK3-related condition
This trial tests a gene therapy called JAG201 for children with a SHANK3 mutation or 22q13.3 deletion, which causes Phelan-McDermid syndrome. The goal is to see if it can help with development and daily function.
Chicago, IllinoisAges 2–9 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT06666777Recruiting
Speech therapy and parenting for early communication skills
This study tests a program that combines speech therapy with parenting support to help young children with developmental delays improve their communication and social skills. It is designed for children aged 6 months to 5 years who have developmental challenges, and their parents.
Como, ComoAges 6 months–4.9 years - NCT06664970Enrolling by invitationPhase 2
Treatment for MDS/MPN Overlap Syndrome
This study tests a combination of two drugs (azacitidine or ruxolitinib plus selinexor) for people with MDS/MPN overlap syndrome, a type of blood cancer. It aims to see if this treatment helps control symptoms and improve blood counts.
BeijingAges 18 years+ - NCT04532424Recruiting
Brain stimulation for repetitive behaviors in autism
This trial tests whether transcranial magnetic stimulation (a non-surgical treatment using magnets on the scalp) can reduce restricted and repetitive behaviors seen in autism. It’s designed for people with autism who have high levels of certain repetitive behaviors, like insistence on sameness or unusual interests.
Stanford, CaliforniaAges 12–45 - NCT05329935Recruiting
Registry for children with congenital thymus missing
This registry follows children born with congenital athymia (a missing or non-working thymus). It collects information around treatment with RETHYMIC, which may help researchers better understand how care and outcomes look over time.
Durham, North CarolinaAges birth–21 years - NCT06378437RecruitingPhase 1
GLB-001 for blood cancers that have returned or not responded
This trial is testing a new drug called GLB-001 for people with certain blood cancers or bone marrow disorders that have not gotten better with standard treatments. The goal is to see if the drug is safe and how well it works.
Hefei, AnhuiAges 18 years+ - NCT06656494RecruitingPhase 1
New drug combo for myeloid blood cancers
This trial tests a new drug (ICP-248) combined with standard treatment azacitidine for people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). It aims to find out if the combo is safe and effective for those who haven't been helped by other treatments or cannot have strong chemotherapy.
Orange, CaliforniaAges 18 years+ - NCT06653985Recruiting
Hip injection plus physical therapy for mild hip problems
This trial tests a combination of a steroid and lubricant injection into the hip joint plus physical therapy to treat mild hip arthritis or related issues like a labral tear. It aims to see if this approach can reduce pain and improve function without surgery.
Hamilton, OntarioAges 40–60 - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06265519Recruiting
Urine markers for enlarged prostate check
This study looks at two natural substances in urine (BDNF and NGF) to see if they can help doctors understand how the lower urinary tract is working in men with an enlarged prostate. It is a simple, non-invasive test that may lead to better ways to diagnose and treat bladder problems.
IstanbulAges 50–80 - NCT06619574Recruiting
Testing the dental compass for jaw joint positioning
This study tests a new tool called a Dental Compass that helps dentists place your jaw joint back in the right position more accurately and quickly. It may help relieve TMJ pain and improve jaw function.
Gainesville, TexasAges 18–90 - NCT06628674Recruiting
Online videos for recovery after rectal cancer surgery
This trial tests if watching online interactive videos can help people who have had surgery for stage I to III rectal cancer deal with common bowel problems after treatment. Your participation could lead to better support tools for other patients.
Taoyuan, 中和區Ages 20 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.