Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07233421Enrolling by invitation
Blood sugar levels in children with Long QT syndrome on beta-blockers
This study looks at how often low blood sugar (hypoglycemia) happens in young children with Long QT syndrome who take beta-blocker medicine. It may help doctors understand if these children need extra monitoring.
HelsinkiAges Up to 7 years - NCT07219485Enrolling by invitationPhase 3
Pitolisant for Prader-Willi syndrome in ongoing study
This study tests an oral medication, pitolisant, in people with Prader-Willi syndrome who have already been in a pitolisant study. It aims to see if continuing treatment is safe and effective.
Morrisville, North CarolinaAges 7 years+ - NCT07183020Enrolling by invitation
Kappa Free Light Chains in MS and CIS
This study looks at a protein called kappa free light chains (KFLC) in the spinal fluid and blood of people with multiple sclerosis (MS) or a first MS-like episode (CIS). The goal is to better understand how this protein relates to the disease, which may help with diagnosis and monitoring.
Hanover, Lower SaxonyAges 18–70 - NCT07142135Enrolling by invitation
Long-term follow-up for Klinefelter syndrome patients
This study follows patients with Klinefelter syndrome over time to learn more about their health. It may help doctors better understand and care for people with this condition.
CopenhagenAges Any age - NCT07102849Enrolling by invitation
Studying bone marrow failure with biospecimens and data
This study analyzes blood, bone marrow, and medical information from people with bone marrow failure syndromes (BMFS) and healthy volunteers to better understand these conditions and find new ways to help patients.
Bethesda, MarylandAges 2–120 - NCT07090382Enrolling by invitation
Predicting shock risk in heart attack patients
This study uses an AI tool to predict which patients with a heart attack might develop cardiogenic shock, a serious complication where the heart can't pump enough blood. It aims to help doctors identify high-risk patients early.
BratislavaAges 18 years+ - NCT07065357Enrolling by invitationPhase 3
A study on a diabetes drug for metabolic syndrome
This trial tests if empagliflozin, a medication typically used for diabetes, can help people with metabolic syndrome (a cluster of conditions like large waist size, high blood sugar, and high blood pressure). It may improve health and reduce the risk of heart disease.
Hong KongAges 18–85 - NCT07051733Enrolling by invitation
Health literacy program for metabolic syndrome
This study tests a health information literacy program to help people with metabolic syndrome better understand and manage their health. It aims to see if the program improves how they take care of their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07032246Enrolling by invitation
AI-assisted care for multiple sclerosis
This study uses artificial intelligence to help doctors better manage MS care. It uses MRI scans and a phone app to track your condition over time.
Prague, PragueAges 18 years+ - NCT07000825Enrolling by invitation
Yerba mate extract for improving metabolic health in overweight adults
This trial tests whether a daily yerba mate extract can help reduce metabolic syndrome in overweight people. You would take the extract for a period while keeping your usual diet and activities.
Realeza, ParanáAges 40–65 - NCT06986668Enrolling by invitation
Warm wax and mud therapy for carpal tunnel syndrome
This trial tests if paraffin wax baths and peloidotherapy (mud therapy) help reduce symptoms of mild to moderate carpal tunnel syndrome (a hand nerve condition). It may be a good fit if you haven't had prior wrist surgery, steroid injections, or other nerve problems.
KonyaAges 18–65 - NCT06908473Enrolling by invitationPhase 3
Tongmai Jiangtang capsule for heart risks in metabolic syndrome
This trial tests whether the Tongmai Jiangtang capsule can reduce serious heart and stroke problems in older adults with metabolic syndrome who are also at high risk for heart disease. It focuses on people with a specific traditional Chinese medicine pattern called Qi-deficiency and Blood Stasis.
Guangzhou, GuangdongAges 65 years+ - NCT06843811Enrolling by invitationPhase 2
Sirolimus for Leigh Syndrome
This trial tests if sirolimus can help people with Leigh syndrome. It aims to see if the drug can improve neurological symptoms and is looking for participants aged 6 months to 55 years.
Philadelphia, PennsylvaniaAges 6 months–55 years - NCT06813625Enrolling by invitation
Shared reading for mental well-being in young people
This trial tests whether reading books together can improve mental well-being in young people with and without Down syndrome. It involves children with Down syndrome and college students from the University of Macau reading together.
MacauAges 2–35 - NCT06808321Enrolling by invitation
Benidipine for high blood pressure or chest pain
This study looks at how well Benidipine works for people with high blood pressure or stable chest pain from heart disease. If you are already taking Benidipine for at least a month, this trial may help doctors learn more about its benefits.
AntalyaAges 18–80 - NCT06798493Enrolling by invitation
CRPS and chronic pain measurement study
This study is testing a new way to measure CRPS symptoms and other chronic pain in one arm or leg. It aims to help doctors better understand and treat your condition.
New York, New YorkAges 18 years+ - NCT06786754Enrolling by invitation
Skin cell study for Marfan syndrome and aortic aneurysms
This study looks at skin cells (fibroblasts) from people with Marfan syndrome or other genetic conditions that cause thoracic aortic aneurysms. The goal is to understand how these cells behave, which may help improve future treatments.
San Donato Milanese, MilanAges 18 years+ - NCT06785766Enrolling by invitation
Yoga for PMS: Balance, focus, and body awareness
This trial tests whether yoga can help with PMS symptoms like poor balance, brain fog, and posture. It looks at how yoga might improve your body awareness and overall well-being during your menstrual cycle.
Siirt, Si̇i̇rtAges 18 years+ - NCT06780657Enrolling by invitation
Hypopressive exercises for overactive bladder syndrome
This trial tests a gentle exercise method (hypopressive exercises) for people with overactive bladder. The exercises involve special breathing and posture techniques to help strengthen the pelvic floor without putting strain on the body.
Denizli, DenizliAges 18–65 - NCT06758518Enrolling by invitation
Carpal tunnel syndrome in medical students: stress and depression
This study looks at how stress and depression might affect carpal tunnel syndrome in medical students. It could help us understand if emotional health plays a role in this common wrist condition.
Ioannina, EpirusAges Any age - NCT06758193Enrolling by invitation
Testing a hand symptom scale for carpal tunnel syndrome
This study tests whether a hand-related questionnaire called the MAP-Hand Scale is a reliable and accurate tool for people with carpal tunnel syndrome. If you have mild to moderate carpal tunnel syndrome in one hand, your answers could help improve how doctors measure symptoms.
Kırşehir, MerkezAges 18–65 - NCT06717477Enrolling by invitation
Improving care for carpal tunnel syndrome patients
This trial tests a new streamlined care pathway for patients with carpal tunnel syndrome. It aims to make appointments and treatments easier and faster.
Vancouver, British ColumbiaAges 18 years+ - NCT06707714Enrolling by invitation
Metabolic benefits after stomach cancer surgery
This study looks at how stomach cancer surgery affects metabolic syndrome (high blood pressure, diabetes, and related conditions). It aims to understand why some patients see improvements in these conditions after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06679790Recruiting
Understanding changes in Tourette Syndrome over time
This study tracks how tics and related symptoms change over time in people with Tourette Syndrome. It aims to better understand the condition and could help develop better treatments.
Minneapolis, MinnesotaAges 12–17
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.