Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07652879RecruitingPhase 2
KCD drug combination for newly diagnosed POEMS syndrome
This trial tests a combination of three drugs (carfilzomib, cyclophosphamide, and dexamethasone) for people newly diagnosed with POEMS syndrome. It aims to see how well this treatment helps control the disease and its symptoms.
ShanghaiAges 18–75 - NCT07653789Recruiting
Hand exercises for carpal tunnel in pregnancy
This study compares three types of hand and wrist exercises to see which works best for mild to moderate carpal tunnel syndrome during pregnancy. It may help reduce pain and improve hand function.
Islamabad, ICTAges 18–45 - NCT07655492Recruiting
Tailored brain training for Sturge-Weber syndrome
This study tests a personalized memory and thinking skills program designed for people with Sturge-Weber syndrome. It aims to see if this program can help improve daily life and brain function.
Roma, RomaAges 2 years+ - NCT07659444Recruiting
Metformin withdrawal study for metabolic syndrome
This study looks at what happens when people with metabolic syndrome temporarily stop taking metformin. It aims to understand how their bodies respond when the medication is paused for 14 days.
Toledo, ToledoAges 18 years+ - NCT07668011Recruiting
Shockwave therapy for iliotibial band syndrome
This study tests whether a type of sound wave therapy (radial shockwave) can help relieve pain from iliotibial band syndrome (ITBS) in active adults. If you have outer knee pain when running and have been diagnosed with ITBS in the last month, you may be able to join.
Giza, Giza GovernorateAges 18–45 - NCT07668908Enrolling by invitation
Virtual reality exercise program for Down syndrome
This trial tests whether an immersive virtual reality exercise program can help people with Down syndrome improve their fitness and health. Participants will do high-intensity workouts in a virtual reality environment.
Pontevedra, PontevedraAges 16–50 - NCT07640503Enrolling by invitationPhase 2
Lamivudine Treatment Study for Rett Syndrome
This study tests whether lamivudine, a medication originally used for HIV, might help improve symptoms in people with Rett syndrome. Researchers will monitor how safe and effective the treatment is over time.
Fortaleza, CearáAges 2 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07578168Enrolling by invitation
Kinesio Tape for Rotator Cuff Shoulder Pain
This study tests whether kinesiology tape (a special stretchy tape applied to the skin) can reduce pain and improve function in people with rotator cuff syndrome, a common shoulder condition. You'll be randomly assigned to receive the tape or a control treatment and tracked over several weeks.
Kırşehir, MerkezAges 18–65 - NCT07563101Enrolling by invitation
Understanding Visual Hallucinations in Low Vision Patients
This study investigates Charles Bonnet Syndrome, which causes people with significant vision loss to see things that aren't there (visual hallucinations). Researchers want to better understand why this happens and how it affects patients' quality of life.
RomaAges 40–70 - NCT07502573Enrolling by invitation
Comparing two exercise programs for piriformis syndrome
This trial compares a home exercise program with a telerehabilitation program for people with piriformis syndrome. Researchers want to see which approach helps reduce pain and improve function better.
Ankara, KeciorenAges 18–45 - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT07486284Enrolling by invitation
Ultrasound test for carpal tunnel syndrome
This trial uses a special ultrasound technique to check for carpal tunnel syndrome (a condition where a nerve in your wrist gets squeezed, causing numbness or pain in your hand). It compares people with the condition to healthy volunteers to see if the ultrasound can help diagnose it.
Da NangAges 18 years+ - NCT07471490Enrolling by invitation
Stool test study for inflammatory bowel disease vs. irritable bowel syndrome
This study collects stool samples and health information to help develop a new test that may tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have not been diagnosed with a chronic gut disorder, you may be able to join.
Minneapolis, MinnesotaAges 2 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT07464639Enrolling by invitation
Comparing two ways to help shoulder pain with movement feedback
This study compares using ultrasound images (dynamic visual feedback) versus manual guidance to help activate shoulder blade muscles and improve space in the shoulder joint for people with shoulder pain when lifting their arm.
Long Beach, CaliforniaAges 18–70 - NCT07413224Enrolling by invitation
Effects of AEF0217 in People with Down Syndrome
This study looks at the effects of a medication called AEF0217 in people with Down syndrome. It is for participants who have already completed an earlier study of AEF0217 and their caregivers.
BarcelonaAges Any age - NCT07380373Enrolling by invitation
Testing markers in body fluids for lung injury in children
This study looks at two substances in saliva and lung fluid—called IL-6 and TNF-α—in children with severe lung failure (ARDS) who are on a breathing machine. Measuring these markers may help doctors better understand the condition and guide treatment.
CairoAges 1–10 - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT07322185Enrolling by invitation
Comparing two bodywork methods for piriformis syndrome
This study compares two hands-on treatments, Stecco-fascial manipulation and Rolfing, for people with piriformis syndrome—a condition that causes buttock pain. The goal is to see which approach works better for reducing pain and improving movement.
Sambrial, Punjab ProvinceAges 25–45 - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT07312136Enrolling by invitation
Liver health follow-up in type 2 diabetes
This study follows up on people who already joined the EPSONIP trial to check how their liver health (MASLD) has changed over time. It uses MRI to look at the liver and does not test any new medicine.
Linköping, Östergötland CountyAges 18 years+ - NCT07298603Enrolling by invitation
Nutrition plan for women with PCOS
This study tests whether a specific nutrition plan can help women with PCOS improve their health. You would follow a guided diet and have check-ins to see how it affects your symptoms and well-being.
Samsun, AtakumAges 20–45 - NCT07253298Enrolling by invitation
Kegel exercises with biofeedback for bowel recovery after rectal cancer surgery
This trial studies whether doing Kegel exercises with biofeedback (a technique that helps you see how your muscles are working) can improve bowel function, reduce emotional distress, and boost quality of life after rectal cancer surgery.
TaipeiAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.