Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,060 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02762162Recruiting
Registry of heart artery patients’ platelet test results
This registry collects information from people with coronary (heart) artery disease who already had platelet-related blood tests as part of usual care. The goal is to better understand how platelet responses relate to treatment and outcomes, which may help future care.
ParisAges 18 years+ - NCT03473912Recruiting
Rheumatoid disease biobank study for adults
This study asks adults with a rheumatoid condition to join a biobank, which is a safe place to store health information and biological samples for future research. It may help researchers better understand rheumatoid conditions and develop better treatments.
Kfar SabaAges 18–120 - NCT03991507Recruiting
Study for people with polycystic ovary syndrome (PCOS)
This study is looking for people who have PCOS based on a specific medical diagnosis standard called the Rotterdam criteria. If you match that diagnosis, the study may test treatments or strategies for PCOS and how well they work.
Zhengzhou, HenanAges 18–40 - NCT04149496Recruiting
IVF cycle study using modified egg-retrieval timing
This study tests an IVF approach that changes how ovarian stimulation is started, helps retrieve eggs more effectively, and may delay embryo transfer. It may help people who have many small eggs (called antral follicles) and higher AMH levels, which can affect how IVF works.
Jacksonville, FloridaAges 18–38 - NCT04218344Recruiting
Heart attack and chest pain study at Harefield hospital
This study follows people who come to Harefield for urgent heart-related chest pain and planned heart-vessel imaging (coronary angiography). It aims to better understand these conditions and what doctors see during the procedure, which may improve care for future patients.
Harefield, MiddlesexAges Any age - NCT03040583Recruiting
Study of people with primary Sjögren’s syndrome
This study follows adults with primary Sjögren’s syndrome. It may help researchers understand the condition better by using information from people who have already joined the earlier ASSESS study.
Le Kremlin-Bicêtre, Val De MarneAges 18 years+ - NCT04371042Recruiting
Study of liver disease and genes in people with fatty liver
This study collects information about metabolic and unexplained (cryptogenic) liver disease and looks at “omics” tests, which are lab tests that measure patterns in blood or tissue to learn what drives the disease. It may help researchers better understand fatty liver and related serious complications, like liver scarring and liver cancer.
Roma, Rome/lazio/italyAges 18 years+ - NCT04407780Recruiting
Cardio-oncology patient registry
This is a registry (a research database) for people who are being followed in cardio-oncology, which means care for heart problems related to cancer or cancer treatments. It may help doctors better understand these conditions and improve future care.
ParisAges 18 years+ - NCT04538937Recruiting
Study of high eosinophils causing lung/airway damage
This registry study looks at adults with high eosinophils (a type of immune cell) that are believed to be causing damage in the airways or lungs. It aims to better identify these eosinophils and understand what is going on so future treatments can improve.
InnsbruckAges 18 years+ - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT03261934Recruiting
Modeling risk and progression in chronic stomach lining disease
This study looks at people with chronic atrophic gastritis to estimate who may be at higher risk of stomach cancer over time. It collects symptom and medical data, plus blood and tissue samples, to build prediction models that may improve future care.
Beijing, Beijing MunicipalityAges 18–75 - NCT04781790Recruiting
Registry for bone marrow failure patients
This study is a national registry that collects health information and some blood or tissue samples from people diagnosed with bone marrow failure. It helps researchers understand causes and long-term outcomes, and may improve care by building a large patient database.
ParisAges Any age - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT03569826Recruiting
Study for primary biliary cholangitis and autoimmune hepatitis
This study is for people diagnosed with primary biliary cholangitis or autoimmune hepatitis. It aims to learn more about these autoimmune liver conditions and may help guide better care in the future.
Calgary, AlbertaAges 18 years+ - NCT04302116Recruiting
Vigabatrin plus high-dose steroid versus vigabatrin alone
This trial tests whether adding a high-dose steroid (prednisolone) to vigabatrin works better than vigabatrin alone for infants with infantile spasms. It may help reduce seizures and improve early development, but your child’s prior treatments and health conditions must fit the study rules.
Ratchathewi, BangkokAges 2 months–1.2 years - NCT05030259Recruiting
Study of recovery after thigh artery injuries
This trial looks at outcomes in adults who have injuries to the femoropopliteal (thigh-to-knee) artery. It may help doctors understand what affects recovery and discharge, especially for preventing complications.
Shijiazhuang, HebeiAges 18 years+ - NCT05043571RecruitingPhase 1
CAR T-cell therapy for relapsed T-cell leukemia
This early-phase trial tests a lab-made immune cell treatment (CAR T-cells) aimed at T-cell leukemia that has come back or did not respond. It may help by targeting leukemia cells with a specific marker (CD7), especially in patients who failed standard treatment.
SingaporeAges 6 months–65 years - NCT03218332Recruiting
Study of concussion symptoms in professional athletes
This study looks at persistent symptoms after concussions in professional athletes and compares different concussion histories. It aims to understand what contributes to ongoing problems and whether certain patterns can be identified to guide better care.
Toronto, OntarioAges 25–85 - NCT03418857RecruitingPhase 1/Phase 2
Probiotics for weight- and blood-sugar–related gut health
This trial tests whether taking probiotics can improve gut health in people with early metabolic problems related to extra body fat, cholesterol, blood pressure, or blood sugar. It’s a Phase 1/2 study, meaning safety and early effectiveness are being tested.
University Park, PennsylvaniaAges 55–75 - NCT04308564Recruiting
Study of lab and clinic data in antiphospholipid patients
This study looks at lab results and clinic information in people who have antiphospholipid antibodies. The goal is to better understand these antibody-positive conditions and what happens over time, which may help improve care.
LilleAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT05177562Recruiting
Study of hormone and pregnancy blood conditions in women
This study looks at hormone and blood test patterns in certain women, including those with PCOS, repeat miscarriages, or specific pregnancy sugar/itching conditions. It may help doctors better understand what’s going on and how these conditions relate to reproductive outcomes.
Oxford, OxfordshireAges 16–45 - NCT05185609Recruiting
Tests anal function in people with inflammatory bowel disease
This study checks how well the anal area works in people with inflammatory bowel disease (IBD), even when your bowel disease is “in remission” but you may still have symptoms. It may help doctors better understand the cause of ongoing problems and guide future care.
ÖrebroAges 18–65
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,060 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.