Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06642636Recruiting
Virtual reality before ICU for lung transplant patients
This study tests if a virtual reality experience before entering the ICU can help prepare you. It is for people waiting for a lung transplant.
Rotterdam, South HollandAges 18–71 - NCT07348341Recruiting
Laser treatment for blocked heart arteries registry
This study collects information from patients with blocked heart arteries who receive a special laser treatment (ELCA) to open the blockage. It will help doctors understand how well this laser works in different situations.
MadridAges 18 years+ - NCT07348081Recruiting
Digital support program for caregivers of ER patients
This trial tests a digital program that helps caregivers coordinate and monitor care for adults leaving the emergency department. It may reduce stress and make caring easier.
ParisAges 18 years+ - NCT07351006Recruiting
Exercise for menopause symptoms
This study tests whether a supervised exercise program can help relieve menopausal symptoms without using medication. If you are 45-55 and bothered by symptoms like hot flashes, poor sleep, or mood swings, you may be able to join.
KalmarAges 45–55 - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT07347418RecruitingPhase 1
CD64 CAR T cell therapy for relapsed or refractory AML
This trial tests a type of immunotherapy called CAR T cells that target a protein called CD64 on leukemia cells. It is for adults with AML that has come back or not responded to treatment, including venetoclax.
Aurora, ColoradoAges 18 years+ - NCT07347171RecruitingPhase 1
Testing CG009301 for blood cancers that returned or didn't respond
This trial tests a new drug called CG009301 for people with blood cancers that have come back or haven't responded to standard treatments. The goal is to see if the drug is safe and works against these cancers.
NanchangAges 18–75 - NCT07352254Recruiting
At-home medical care for housebound ME/CFS patients
This study is testing a way to improve medical care for people with ME/CFS (including post-COVID ME/CFS) who are mostly homebound. The goal is to see if bringing healthcare to your home helps you better manage your condition.
HanoverAges 18–69 - NCT07335523Recruiting
Testing for poor digestion in Alagille syndrome after liver transplant
This study looks for signs of poor digestion after a liver transplant in people with Alagille syndrome. You collect stool samples for 3 days while on a high-fat diet to see if your pancreas is making enough enzymes.
Aurora, ColoradoAges 7–50 - NCT07334444Recruiting
Improving sleep apnea care for children with Down syndrome
This study looks at how sleep apnea is managed in children with Down syndrome. It aims to find better treatment approaches by reviewing data from kids who visited ear, nose, and throat (ENT) or sleep specialists in Strasbourg.
StrasbourgAges birth–17 years - NCT07339189Recruiting
AI Suicide Prevention for Older Adults With HIV
This trial tests a smartphone-based AI program designed to help people with HIV who have had suicidal thoughts. It aims to reduce suicide risk by teaching coping skills through text-based conversations.
Newark, New JerseyAges 50 years+ - NCT07338929Recruiting
Physical performance test for kidney transplant evaluation
This study measures physical performance in adults being evaluated for a kidney transplant. It helps understand how fitness levels may affect transplant outcomes.
MartinAges 18 years+ - NCT07336394Recruiting
Study on rare heart muscle diseases using advanced MRI
This study uses a special heart MRI to better diagnose and understand rare heart muscle diseases. It may help doctors predict risks and make more accurate treatment decisions.
BeijingAges Any age - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT06701968Recruiting
Healthy Nordic diet for heart artery health after heart attack
This study tests whether a healthy Nordic diet (like whole grains, berries, fish, and vegetables) can slow down hardening of the arteries in people who have had a heart attack or have stable chest pain. It lasts 18 months and aims to improve heart health.
UppsalaAges 50–80 - NCT07327775Recruiting
ADHD and fibromyalgia in mothers
This study looks at how having fibromyalgia affects mothers who also have a child with ADHD. It compares them to mothers of children without ADHD to see if the burden of care is different.
EdirneAges 18–50 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06864520Recruiting
GABA supplement for menopause symptoms
This study tests whether a natural supplement containing GABA (a chemical that helps calm the brain) can reduce menopause symptoms like hot flashes, mood swings, and sleep problems. It may be a good option if you are looking for a non-hormonal way to manage your symptoms.
Genova, ItaliaAges Any age - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07325110Recruiting
Teens with chronic pain: yoga in occupational therapy
This study looks at whether adding yoga to occupational therapy helps teens with chronic pain better understand their body's signals. It aims to improve daily function and well-being.
Hartford, ConnecticutAges 11–21 - NCT07327684Recruiting
Imaging brown fat activity with ultrasound
This study uses a special camera (photoacoustic/ultrasound) to look at a type of fat called 'brown fat' that helps your body burn energy. You may be able to join as a healthy volunteer or if you have a condition like type 2 diabetes or PCOS.
BeijingAges 18–80 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.