Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT05261607Recruiting
Study outcomes for people in the intensive care unit
This study looks at how mortality (whether patients survive) changes over time for people treated in an intensive care unit. It may help hospitals understand what happens to ICU patients and improve care planning.
Getafe, MadridAges Any age - NCT05274854Recruiting
Practice change study for severe unexplained gut symptoms
This study looks at a new approach to care for adults with severe, long-lasting stomach or bowel symptoms when no clear cause has been found. It may help you get more coordinated support through an integrated care clinic.
Woolloongabba, QueenslandAges 18–90 - NCT05279963Recruiting
Study for bladder pain using a nerve-based treatment (EA)
This trial tests whether a nerve-based therapy called EA can reduce bladder pain. It also aims to understand why the treatment may help by looking at underlying mechanisms.
Hangzhou, ZhejiangAges 18–70 - NCT05284006Recruiting
Non-invasive tests for Morquio A
This trial studies Morquio A (MPS IVA) using non-invasive ways to measure how the body is working, and to better understand why the condition happens. If you have Morquio A, this may help researchers learn more and improve care.
Wilmington, DelawareAges Any age - NCT05293769Recruiting
Food diary questionnaire test for IBS and activity levels
This study checks whether a food questionnaire can reliably estimate what you eat, including certain carbs that can affect digestion (FODMAPs). It also looks at how the results relate to IBS symptoms and your self-reported physical activity.
Jette, Brussels CapitalAges 18–65 - NCT05305482Recruiting
Compare two stents after heart attack treatment
This trial compares two types of stents that release medicine to help keep arteries open after an acute coronary syndrome event (often called a heart attack or unstable angina). It tests whether the standard short course of two blood-thinning medicines for one month is enough, and which stent strategy works best.
SeoulAges 19 years+ - NCT05315895Recruiting
Study of people with “dampness” signs in Chinese medicine
This is an observational study that looks at a Chinese-medicine pattern called “dampness” by collecting health and biological information from volunteers. It may help researchers better understand what this pattern looks like and how it relates to people’s health.
Guangzhou, GuangdongAges 35–79 - NCT05321355Recruiting
Sleep disorder patient registry for narcolepsy and other conditions
This is a research registry that collects information from people with narcolepsy and other neurological sleep disorders. It may help doctors better understand sleep problems and improve future care.
Mainz, Rhineland-PalatinateAges 18–120 - NCT05325034Recruiting
Lipid-lowering plan after heart attack in adults
This study tests a cholesterol-lowering treatment plan for adults admitted for a Type 1 heart attack. It may help your care team choose guideline-based cholesterol goals and treatments after the event.
Wollongong, New South WalesAges 18 years+ - NCT05326919Recruiting
Study biobank for people newly diagnosed with certain blood cancers
This study follows people who are newly diagnosed (and haven’t been fully treated yet) with specific leukemia or related blood disorders to help researchers learn which treatments may work best. It may help by connecting you to a larger “precision medicine” patient group for future research.
BobignyAges Any age - NCT05339529Recruiting
Thymosin A1 to help protect organs after emergency aortic surgery
This study looks at whether thymosin A1 can reduce immune-related problems and organ injury after emergency surgery for an acute aortic condition. If you qualify, you may receive thymosin A1 as part of the treatment plan to see if it improves recovery.
Bengbu, AnhuiAges 18–90 - NCT05342584RecruitingPhase 1
Venetoclax plus intensive chemo for AML and advanced MDS
This early-phase study tests whether venetoclax combined with intensive chemotherapy can treat AML (acute leukemia) and certain advanced MDS. It’s for people who are newly diagnosed (or certain high-risk blood cancers) and can safely tolerate strong treatment.
The Bronx, New YorkAges 18–75 - NCT05343572RecruitingEarly Phase 1
Stem cell treatment to improve abnormal uterine lining
This early-phase study tests whether mobilized stem cells from bone marrow can help women with certain abnormal uterine lining problems become healthier and possibly improve fertility. It’s aimed at people who are not pregnant and meet specific diagnoses and test results.
Orange, ConnecticutAges 18–40 - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT05347069RecruitingPhase 4
Aspirin study for people with stable heart artery disease
This trial tests whether daily aspirin is safe and effective for people who have stable (chronic) coronary artery disease but cannot have procedures to open blocked arteries. It may help reduce future heart problems, while also checking for side effects and risks from aspirin.
KyotoAges 20 years+ - NCT05348564Recruiting
Family genetic screening methods for heart rhythm risk
This study compares two ways to find relatives who may carry a specific inherited genetic change. It may help your family learn faster who should get follow-up testing and care.
Lancaster, PennsylvaniaAges 18 years+ - NCT05355272RecruitingPhase 2
Growth hormone treatment for Gulf War illness with low growth hormone
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
Houston, TexasAges 18–64 - NCT05355415Recruiting
Eye imaging study for outer retina diseases using adaptive optics
This study uses a special, high-detail eye imaging machine to take clear pictures of the outer retina. It may help researchers understand these eye conditions better, and how the eye images look when people have an outer retinal disease.
Bethesda, MarylandAges 21 years+ - NCT05365282Recruiting
Check how a wrist artery procedure affects hand nerve symptoms
This study looks at whether a procedure on an artery in the wrist is linked to new or worsening nerve symptoms in the hand. It may help doctors understand who is at higher or lower risk and improve safety.
AarhusAges 18 years+ - NCT05366452Recruiting
Early heart pump implant for shock after a heart attack
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Marseille, Bouche DU RhoneAges 18–80 - NCT05372393Recruiting
Carpal tunnel surgery with local anesthesia, with or without nerve block
This study compares two ways of giving pain control during carpal tunnel release surgery: local anesthesia alone versus local anesthesia plus a targeted nerve block. It may help find the safest and most comfortable option for people having carpal tunnel surgery.
Kuopio, Northern SavoniaAges 18 years+ - NCT05382754Recruiting
Home sleep testing for children being checked for sleep apnea
This trial tests whether home sleep testing can help diagnose sleep apnea in children. It is for kids who are already being referred for an in-lab sleep study at CHOP.
Philadelphia, PennsylvaniaAges 5–12 - NCT05384691RecruitingPhase 2
Luspatercept for anemia in lower-risk MDS not needing transfusions
This Phase 2 trial studies whether luspatercept can improve anemia in people with lower-risk myelodysplastic syndrome (MDS) who do not currently need red-blood-cell transfusions. It’s also looking to see if the benefit is similar whether or not you have ring sideroblasts.
BerlinAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.