Clinical trials
Drug Use clinical trials
Below are recruiting drug use clinical trials, each written for real people, not researchers. We’re tracking 143 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05722561RecruitingPhase 2
E-cigarettes to reduce smoking in opioid use disorder
This Phase 2 study tests whether e-cigarettes can help people who use opioids (and also smoke cigarettes) cut down on combustible cigarette smoking. It looks at whether switching to e-cigarettes for “harm reduction” is safe and helps you smoke fewer cigarettes without requiring you to quit completely.
New York, New YorkAges 21–75 - NCT05957848RecruitingPhase 2
Guanfacine for teens with cannabis use problems
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Parkville, VictoriaAges 12–25 - NCT06115746Recruiting
A drug education program for middle and high school students
This study tests a program called iDECIDE, which helps students who have had a substance use issue at school. The program aims to provide education and support instead of punishment. Participants will attend up to 9 online study visits over about a year.
Boston, MassachusettsAges 9–22 - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06759623Recruiting
Lung function and anesthesia in bariatric surgery
This study checks how well your lungs work after you receive anesthesia (sleep medicine) for weight-loss surgery. It will help doctors choose the best anesthetic for people with obesity.
GdanskAges 18 years+ - NCT07491380Recruiting
Blood monitoring for breast cancer drugs at home
This study tests a finger-prick blood test you can do at home to check levels of your breast cancer medication (ribociclib, abemaciclib, or palbociclib). The goal is to make monitoring easier and more convenient.
ParisAges 18 years+ - NCT06409884Recruiting
Amoxicillin allergy testing trial
This trial is testing a new way to diagnose allergies to amoxicillin, a common antibiotic. It may help people who think they might be allergic to amoxicillin find out for sure.
Edegem, AntwerpAges 6 years+ - NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT07344363Recruiting
Prostate cancer hormone drug level monitoring study
This study looks at how levels of common prostate cancer hormone treatments (abiraterone, apalutamide, darolutamide, or enzalutamide) stay in your blood over time. By checking drug levels, doctors hope to personalize dosing to make treatment safer and more effective.
Aviano, PordenoneAges 18 years+ - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Birmingham, AlabamaAges 18 years+ - NCT06793293Enrolling by invitation
Laser therapy for c-section incision pain
This trial tests if a high-level laser can reduce pain and help healing after a cesarean section. If you've had a C-section and have incision pain, this treatment may offer relief without medication.
CairoAges 20–40 - NCT07858565Recruiting
Quality of life with quetiapine for schizophrenia or bipolar disorder
This study looks at how well patients feel and how safe it is when taking quetiapine alone or with other medicines for schizophrenia or bipolar disorder. It aims to help doctors understand the best ways to use this treatment.
SarajevoAges 18–65 - NCT07432867RecruitingPhase 1/Phase 2
Gene therapy for severe sickle cell disease in teens and adults
This trial tests a new gene therapy for sickle cell disease. It uses your own blood stem cells (collected from bone marrow) that are modified in a lab to help produce healthy red blood cells, then given back to you after a short chemotherapy. The goal is to reduce or stop severe complications like pain crises and lung problems.
Paris, Île-de-France RegionAges 12–35 - NCT06399107RecruitingPhase 1/Phase 2
Gene therapy trial for sickle cell disease using BAH243
This trial tests a gene therapy that uses a modified virus to deliver a healthy gene to your blood stem cells. It aims to help people with sickle cell disease produce normal red blood cells and reduce painful crises.
Beijing, Beijing MunicipalityAges 2–90 - NCT06644976Recruiting
Bleeding study for hip fracture patients on blood thinners
This trial looks at patients with a broken hip who take a type of blood thinner called a NOAC. It measures bleeding during surgery to fix the hip, without stopping or delaying the surgery. The goal is to see if it is safe to operate right away.
Kfar SabaAges 18 years+ - NCT07330349Recruiting
Trauma and substance use in penetrating abdominal injury
This study looks at alcohol, drug use, and painkiller use in people with a penetrating abdominal injury (like a stab or gunshot wound to the belly). It aims to understand how these substances affect patient outcomes.
Cali, Valle del Cauca DepartmentAges 15 years+ - NCT05770622RecruitingPhase 4
Vancocin dosing check in young infants with infections
This trial studies a better way to monitor and adjust vancomycin (an antibiotic) dosing in very young infants. It may help your baby get the right dose while reducing the risk of under- or over-dosing.
Melbourne, VictoriaAges birth–3 months - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT07771283Enrolling by invitation
Comparing ovarian stimulation methods for IVF
This study compares two methods of stimulating the ovaries before IVF: one using a standard hormone (hCG) and another using a different protocol. The goal is to see if the new method works as well as the standard one, while possibly being more cost-effective.
KampalaAges 18–40 - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT07309094Recruiting
Effects of a diabetes drug on fat tissue in kidney disease
This trial tests whether a GLP-1 receptor agonist (a type of diabetes medication) can improve fat tissue health in people with chronic kidney disease who also have type 2 diabetes, cardiovascular disease, or obesity. It may help protect your kidneys and overall health.
Valencia, ValenciaAges 18–90 - NCT04900623RecruitingPhase 2
Using HPV blood test to guide treatment for HPV throat cancer
This Phase 2 study tests a “risk-adapted” treatment plan for HPV-related throat cancer, using an HPV DNA blood test to help decide how treatment is done. If your baseline blood test shows detectable HPV DNA, the study may help tailor therapy to your risk and potentially improve outcomes while limiting unnecessary treatment.
Boston, MassachusettsAges 22 years+
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Common questions
- Are there clinical trials for drug use?
- Yes. Clin2 currently lists 143 recruiting drug use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.