Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04234971RecruitingPhase 4
Compare costs of bone grafting for cleft jaw repair
This study looks at whether alveolar bone graft surgery is cost-effective for people with cleft lip and palate. It may help clinics choose the most practical approach for the best outcomes while managing overall costs.
Houston, TexasAges 6–15 - NCT04244721Recruiting
Parent training program for children with autism
This trial tests whether a parent-led program (with PACT) can improve autism-related symptoms in children. It focuses on giving parents structured support, and it compares outcomes after families complete the program.
BronAges 1.5 years–3 years - NCT04252547Recruiting
Skin-to-skin care during weighing for preterm babies
This study tests whether “kangaroo care” (skin-to-skin holding) affects how test weights are done for preterm babies in the NICU. It may help staff get more accurate weights and support parents during care.
Istanbul, IstanbulAges 7 months–9 months - NCT04262492Recruiting
Registry of adults with APS on blood thinners
This study keeps an international registry of people with antiphospholipid syndrome (APS) who are taking direct oral blood thinners. It may help doctors better understand how APS patients do over time and improve future care, even if you’re not asked to change treatment.
NancyAges Any age - NCT04267003Recruiting
Brain stimulation study for thinking and brain chemistry in schizophrenia
This study tests whether a brain stimulation approach can improve thinking (cognition) in people with schizophrenia and how it changes brain electrical signals and a brain chemical called GABA. It may help researchers understand new ways to support thinking and symptoms.
Sacramento, CaliforniaAges 18–47 - NCT04273061RecruitingPhase 2
Atezolizumab for tumors that look sensitive on DNA/RNA testing
This Phase 2 study tests atezolizumab, an immunotherapy drug, in people with advanced, incurable solid tumors whose tumor DNA/RNA suggests they may respond. The goal is to see if the treatment works better for patients selected by these lab results.
Vancouver, British ColumbiaAges 18 years+ - NCT04275453RecruitingPhase 1/Phase 2
Test diet vs ketone drinks to reach ketosis safely
This early-stage study compares how quickly and effectively a low-carbohydrate diet versus taking ketone supplements helps the heart use less sugar (measured with PET/CT scans). It also looks at how long it takes to reach a “ketosis” state, which may be helpful for metabolic health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT04299945Recruiting
Beetroot juice to boost exercise in fibrotic lung disease
This trial tests whether drinking beetroot juice can improve exercise performance in people with fibrotic interstitial lung disease (scarring in the lungs). It may help your body use oxygen better during activity if you meet the study’s safety and lung-function requirements.
Vancouver, British ColumbiaAges 19 years+ - NCT04303325RecruitingPhase 4
Esketamine after breast surgery for depression and gut changes
This trial studies whether esketamine given around the time of breast cancer surgery can improve depression and change gut bacteria. It also monitors your sleep/deep anesthesia level (with a simple monitoring number).
Shenyang, LiaoningAges 18–65 - NCT04318041RecruitingPhase 3
Diacerein to improve knee osteoarthritis symptoms
This Phase 3 study tests diacerein (Artrodar®) to see if it can improve symptoms in people with knee osteoarthritis, and it uses movement and scan-based assessments. It may help reduce walking pain and improve knee function for the right patient group.
Bangkoknoi, BangkokAges 40–65 - NCT04320199Recruiting
Fermented beetle powder for alcohol-related liver problems
This trial tests whether a fermented powder made from a specific beetle can improve or protect the liver after alcohol-related liver injury. It’s looking for people with certain liver blood test levels, and it excludes several conditions and recent herbal or liver-affecting treatments.
Pusan, Ami-dongAges 19 years+ - NCT04325958Recruiting
Test how cannabis affects driving in different age groups
This study looks at how smoked cannabis changes driving performance when compared across two age groups. It may help researchers understand safety risks and differences by age.
Toronto, OntarioAges 19–45 - NCT04330729Recruiting
Aspirin effect on blood clotting in kidney disease
This study checks how aspirin (also called salicylate) affects how platelets work, which helps blood clot. It involves people with advanced chronic kidney disease who are treated with Aranesp, and it may help guide safer care.
RoskildeAges 18–85 - NCT04339218RecruitingPhase 3
Cryoablation plus pembrolizumab and chemotherapy for lung cancer spread
This trial studies whether freezing a small number of lung cancer spots (cryoablation) alongside standard immunotherapy (pembrolizumab) and chemotherapy can improve outcomes in people with metastatic lung adenocarcinoma. It’s meant for people who have measurable tumors that can be safely targeted with the freezing treatment.
Bordeaux, GirondeAges 18 years+ - NCT04347434RecruitingPhase 4
Long-term cholesterol medicines after heart attack
This trial studies how well long-term cholesterol-lowering treatment works in people who recently had a heart attack (STEMI or NSTEMI). It may help your care team understand which patients benefit most and how treatment should be continued safely.
PenzaAges 30–70 - NCT04366999Recruiting
Bariatric surgery for fatty liver disease in people with obesity
This trial looks at whether weight-loss (bariatric) surgery helps people with fatty liver disease, including “NASH,” and related liver scarring. If you have obesity and a confirmed liver fat diagnosis (and for NASH, biopsy-proven NASH with some fibrosis), the study may follow your outcomes after surgery.
Beijing, Beijing MunicipalityAges 16–65 - NCT04368663Recruiting
TJ-134 for bowel cysts causing symptoms
This trial looks at whether TJ-134, a traditional herbal medicine, helps people who have symptomatic pneumatosis cystoides intestinalis (bowel cysts). It may help reduce symptoms if the condition matches the typical colonoscopy findings.
Komagane, NaganoAges 18–100 - NCT04373564RecruitingPhase 4
Tracking brain and movement changes after repeated MRI contrast
This study looks at whether getting the MRI contrast dye multiple times over 5 years affects body movement and thinking skills. It compares people who had the dye repeatedly with people who have little or no exposure, using brain MRI scans and regular mental and movement testing.
Scottsdale, ArizonaAges 18–64 - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT04409431Recruiting
Spironolactone plus adrenal nerve treatment for adrenal overactivity
This trial studies whether blocking part of the adrenal blood supply (“adrenal artery ablation”) along with spironolactone can improve hormone-driven high blood pressure caused by primary aldosteronism. It may help people who have confirmed adrenal overactivity and do not want surgery.
Chongqing, Chongqing MunicipalityAges 30–60 - NCT04410003RecruitingPhase 1
Stool-sample capsules to study gut microbiome in unexplained atherosclerosis
This early-phase study tests whether taking stool-based capsules can change gut bacteria in people with severe atherosclerosis that can’t be explained by usual risk factors. Researchers also measure related metabolic (body chemistry) and microbiome (gut bacteria) changes to see how this approach might help.
London, OntarioAges 18 years+ - NCT04411225RecruitingPhase 3
CBD may help early psychosis along with usual treatment
This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.
La Jolla, CaliforniaAges 16–30 - NCT04421768Recruiting
Training for cervical exams in labor and delivery care
This trial studies whether a structured training program helps healthcare staff perform cervical exams more effectively during labor. It may improve how labor and delivery care is delivered at the hospital.
Winston-Salem, North CarolinaAges Any age
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.