Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06980870RecruitingPhase 2
Pain medicine before root canal for less discomfort
This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.
RawalpindiAges 18–50 - NCT05775211Recruiting
PBMC immune therapy added during fertility treatment
This trial studies whether giving your own immune cells (PBMC) to the uterus, modified with interferon (IFN‑t), can improve how endometrial (uterine lining) cells behave during infertility treatment. It may help some people with primary infertility who are undergoing assisted reproduction.
Sofia, SofiaAges 18–50 - NCT05235945Recruiting
Exercise program for people waiting for weight-loss surgery
This trial studies whether an exercise program can help people prepare for bariatric (weight-loss) surgery. It aims to see if exercise is safe and beneficial while you’re waiting for your surgery date.
LondonAges 18 years+ - NCT05192876Recruiting
Review of outcomes and side effects during radiation treatment
This study collects information about results and side effects from people receiving radiation therapy at a specific hospital. It may help improve how radiation treatment is planned and monitored in the future.
Winterthur, Canton of ZurichAges 16–105 - NCT05421364Recruiting
Boosting your own immune cells to improve the uterine lining
This study gives a small amount of your own immune cells into the uterus to change the immune environment in the uterine lining. It aims to improve how the uterine lining supports implantation, especially for people trying to conceive with embryo transfer of normal (euploid) embryos.
Sofia, SofiaAges 20–50 - NCT05775198Recruiting
IVF trial using your own immune cells to support embryo transfer
This trial studies whether placing your own immune cells (PBMCs) that have been adjusted with a medicine called IFN-<i>t</i> before embryo transfer can improve IVF success. It may help support the uterine environment around the time of implantation.
Sofia, SofiaAges 18–50 - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06764225Recruiting
Low-Sodium Salt for Heart Failure Patients
This study tests whether using a low-sodium salt substitute can help people with heart failure live longer, avoid hospital visits, and feel better. It's for adults with a weakened heart pump who have a caregiver and eat home-cooked meals.
Beijing, Beijing MunicipalityAges 18–75 - NCT06244745RecruitingPhase 3
Letrozole after ovarian stimulation in egg donors
This study tests whether giving the drug letrozole after ovarian stimulation can help egg donors. The goal is to see if it reduces the risk of ovarian hyperstimulation syndrome, a side effect that can happen after donating eggs.
MadridAges 18–34 - NCT06971016Recruiting
Mobilization and balance exercises for knee osteoarthritis
This study tests whether a special hands-on technique (Mulligan mobilization) combined with balance exercises can help people with knee osteoarthritis feel better and move easier. It's for people with mild to moderate knee OA who can walk without help.
Karachi, SindhAges 40 years+ - NCT06982079RecruitingPhase 3
SGLT2 inhibitors for advanced kidney disease
This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.
CairoAges 18 years+ - NCT07068074RecruitingPhase 3
Comparing less invasive surgery to standard care for older adults with early-stage melanoma
This trial compares less invasive procedures with the current standard treatment for early-stage melanoma in adults 75 and older. The goal is to find out if these less invasive options work just as well and help patients recover better.
Birmingham, AlabamaAges 75 years+ - NCT07075614Enrolling by invitation
Parent training for kids with autism or high-risk infants
This study tests a parent training program for children with autism or for infants under 2 who show early signs of autism. The program helps parents learn ways to support their child's development.
IstanbulAges birth–5 years - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT06983054RecruitingPhase 4
Salt, kidneys, and ertugliflozin in type 2 diabetes
This study tests if changing how much salt you eat affects how the drug ertugliflozin works in people with type 2 diabetes. You would take either the drug or a placebo (a dummy pill) for a short time while following a low- or high-salt diet, to see how your kidneys and blood vessels respond.
Denver, ColoradoAges 18–85 - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
Huntsville, AlabamaAges 18 years+ - NCT07073950RecruitingPhase 4
A study on a triple inhaler for COPD with hyperinflation
This study tests a triple-combination inhaler (budesonide, glycopyrronium, formoterol) against a placebo inhaler to see how it affects your heart and lungs if you have COPD and over-inflated lungs.
AhrensburgAges 40–80 - NCT07068204Recruiting
Comparing two toothpastes to prevent cavities in healthy adults
This study tests whether a new 2% calcium hypophosphite toothpaste is better than standard fluoride toothpaste at preventing cavities. You may be able to join if you have healthy teeth and are willing to use an electric toothbrush and floss.
Bialystok, PolandAges 18–45 - NCT07073079Recruiting
Study of upadacitinib and risankizumab for Crohn's after first therapy
This study tests two oral/ injectable medicines (upadacitinib and risankizumab) in adults with moderate-to-severe Crohn's who have already tried a TNF-blocker. It aims to see how well these treatments work in everyday practice.
Castellana Grotte, BariAges 18 years+ - NCT06474793Recruiting
Aromatherapy for fatigue and sleep in ICU nurses
This trial tests whether smelling lavender or chamomile essential oils can help intensive care nurses feel less tired and sleep better. If you work night shifts and have trouble sleeping or feel very fatigued, you might be able to join.
Kayseri, KocasinanAges 18 years+ - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06985836Recruiting
Gentle therapy for frozen shoulder: comparing two approaches
This study compares two types of gentle, hands-on physical therapy (Mulligan mobilization with or without the Niel Asher technique) for treating frozen shoulder. It aims to find which approach reduces pain and improves movement better.
Multan Khurd, Punjab ProvinceAges 40–60 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07067424Recruiting
Aromatherapy for anxiety during colonoscopy
This study tests if smelling lavender or bergamot oil can reduce anxiety for people having a colonoscopy. If you are nervous about the procedure, this simple treatment might help you feel calmer.
FamagustaAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.