Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06487078Recruiting
Study of Lorlatinib for untreated ALK-positive lung cancer
This study looks at how well and how safely the drug lorlatinib works in people with a certain type of advanced lung cancer (ALK-positive NSCLC) who have not had treatment for their advanced cancer yet. The goal is to see how effective it is in the real world.
Paris, ParisAges 18 years+ - NCT06494540Recruiting
TDC treatment for advanced non-squamous lung cancer
This study is looking at how well a new treatment called TDC (which includes durvalumab and chemotherapy) works for people with a certain type of advanced lung cancer that has spread and has specific genetic features. It aims to see if this treatment is effective and safe in the real world, and it might be an option if you are starting this therapy anyway.
Bad HomburgAges 18–120 - NCT06493851Recruiting
Hyperbaric oxygen therapy to speed recovery after ACL reconstruction
This trial tests whether hyperbaric oxygen therapy (breathing oxygen in a pressurized chamber) can help you recover faster after ACL knee surgery. If you're having ACL reconstruction, this treatment might reduce healing time.
ZrifinAges 18–45 - NCT06482983Recruiting
Two breathing methods for women having laparoscopic gynecologic surgery
This study compares two ways of helping you breathe during surgery to see which one is better for your brain and lungs. The results may help doctors choose the safest method for people like you.
Istanbul, UmraniyeAges 18–70 - NCT06490731RecruitingPhase 1/Phase 2
Comparing two sedatives for ICU recovery after bowel surgery
This trial tests whether dexmedetomidine or ketamine is better at reducing inflammation and keeping blood pressure stable in patients recovering from emergency abdominal surgery. It may help doctors choose the best sedation for you after surgery.
AsyutAges 18–70 - NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT06490003Recruiting
Predicting chemotherapy success for esophageal cancer
This trial looks at whether a biopsy taken before chemotherapy can help predict how well the treatment will work for people with esophageal squamous cell carcinoma. It aims to improve future treatment decisions.
Chūō, YamanashiAges 20 years+ - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT06491017Recruiting
Better airway clearance for ventilated patients
This trial tests if a special machine (mechanical insufflation-exsufflation) can help remove thick mucus from the lungs of patients who are on a breathing tube and ventilator. The goal is to see if optimized settings clear more mucus than standard care.
BarcelonaAges 18 years+ - NCT06487403Recruiting
Delaying radiation for head and neck cancer: MRI and immune markers study
This study tests whether delaying radiation therapy can help doctors learn more from MRI scans and immune system changes in patients with head and neck cancer. This could lead to better treatment decisions.
Toronto, OntarioAges 18 years+ - NCT06488443Recruiting
Yoga for reducing tobacco cravings
This study tests whether yoga can help men who are dependent on tobacco reduce their cravings. If you are a male tobacco user aged 18 to 65, this trial may offer a non-medicine way to manage your urge to smoke or chew tobacco.
Bengaluru, KarnatakaAges 18–65 - NCT06482515RecruitingPhase 2
Meal timing for fatigue after blood cancer treatment
This study tests whether timing your meals in a certain way can help reduce fatigue in people who have finished treatment for a blood cancer. If you're still struggling with tiredness, this may offer a practical, non-drug approach to feel better.
Baltimore, MarylandAges 18 years+ - NCT06487312Enrolling by invitation
Testing a remote automated ultrasound system for exams
This trial tests a remote, automated ultrasound system that may allow you to get an ultrasound exam without the doctor being in the same room. The goal is to see if it works as well as a standard ultrasound and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT06495593Enrolling by invitationPhase 4
Ocrelizumab's effect on immune cells in lymph nodes in MS
This study tests how ocrelizumab, a medication for MS, affects immune cells in your lymph nodes. It may help doctors understand how the drug works and why it helps some people more than others.
San Francisco, CaliforniaAges 18–65 - NCT06482853RecruitingEarly Phase 1
Heart effects of a natural protein in obesity and high blood pressure
This study tests whether a natural protein called angiotensin-(1-7) can improve heart health in people with obesity and high blood pressure. It may help researchers find new ways to treat these conditions together.
Hershey, PennsylvaniaAges 18–65 - NCT04234724Recruiting
Study of how ANGPTL3 gene variants affect body functions
This study looks at how different ANGPTL3 gene versions may change normal body measurements (such as blood and metabolism). It may help researchers understand why these genetic differences affect health, especially related to fats (lipids) in the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05997407Recruiting
Managing stress through mindset for women with infertility
This study tests a mindset-based program to help reduce stress in women dealing with infertility. It is designed for new patients at two specific fertility clinics who have not yet had fertility treatment with a specialist.
Roanoke, VirginiaAges 18–42 - NCT06304389Recruiting
Blue light therapy for epilepsy with vagus nerve stimulation
This trial tests if blue light exposure can improve the effects of vagus nerve stimulation (VNS) in people with epilepsy that is hard to control. It also includes some healthy volunteers for comparison. The goal is to find new ways to make VNS work better.
Woluwe-Saint-LambertAges 18–60 - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT06468280RecruitingPhase 2
Immunotherapy and chemo with surgery for limited-spread stomach cancer
This trial tests a combination of an immunotherapy drug (PD-1 antibody) plus chemotherapy or targeted therapy, followed by surgery, for people with stomach cancer that has spread to a limited number of other sites. The goal is to see if this approach can help shrink the cancer enough to make surgery more effective.
Shanghai, Shanghai CityAges 18–79 - NCT06473207Recruiting
Can a blood pressure cuff protect the brain after cardiac arrest?
This trial tests if a special blood pressure cuff (like a tourniquet) placed on the leg can protect the brain after a cardiac arrest. It is for patients who are unconscious and on a breathing machine after their heart restarts.
Toulon, VarAges 18 years+ - NCT06464705Recruiting
PEMF Therapy for Hamstring Strength After ACL Surgery
This study tests whether wearing a special device (PEMF) for a few minutes each day can help you regain hamstring strength more quickly after ACL surgery. If your hamstring is still weaker than your other leg at 4 months, this may help you recover better.
ShatinAges 18 years+
Hear when a new Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,360 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.