Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07835399Recruiting
Light therapy for mild cognitive impairment and mild Alzheimer's disease
This trial tests if shining a special light through the scalp and nose can help people with mild memory or thinking problems. It aims to slow down memory decline and improve daily life.
BeijingAges 50–85 - NCT07828860RecruitingPhase 1
Soquelitinib for adults with hidradenitis suppurativa
This trial tests a new oral medication, soquelitinib, in adults with moderate-to-severe hidradenitis suppurativa (HS), the skin condition that causes painful lumps and tunnels. Soquelitinib works by calming the immune system to reduce inflammation. The study aims to see if it is safe and effective.
West Lafayette, IndianaAges 18 years+ - NCT07832552Enrolling by invitationPhase 3
Eye drop treatment for pain and swelling after cataract surgery
This study tests a medication given as an injection during cataract surgery to prevent eye pain and swelling. It aims to see if it helps you recover more comfortably.
Kansas City, MissouriAges 18 years+ - NCT03769129Recruiting
Pembrolizumab plus lung ablation for advanced lung cancer
This trial tests whether combining pembrolizumab (an immune treatment) with a lung ablation procedure can be safer and more effective for advanced non-small cell lung cancer after standard first treatment fails or the cancer comes back. It may help shrink tumors and improve control of the disease.
Guangzhou, GuangdongAges 18 years+ - NCT07829276Enrolling by invitation
Preventing low white blood cell fever during cancer chemotherapy
This study compares different doses of a medication called PEG-rhG-CSF, which is used to help prevent a serious side effect of chemotherapy called febrile neutropenia (fever with a low white blood cell count). The goal is to find the best dose that keeps your blood counts healthy and reduces the risk of infection during treatment.
Hangzhou, ZhejiangAges 18–75 - NCT07827716RecruitingPhase 2
Testing terfenadine for relapsing multiple sclerosis
This study tests whether terfenadine, an allergy medicine, is safe and helpful for people with relapsing-remitting multiple sclerosis (MS). It may reduce MS activity and improve outcomes.
Wuhan, HubeiAges 18–65 - NCT06478225Recruiting
Cell therapy for advanced pancreatic cancer
This trial tests a new cell therapy (BGT007H) for people with advanced pancreatic cancer that has not responded to earlier treatments. The goal is to see if it is safe and can help shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07819435RecruitingPhase 2/Phase 3
Topical treatment for male pattern hair loss
This study tests an investigational topical medication called PP405 for male pattern hair loss. It aims to see if the treatment is safe and effective for regrowing hair in men with moderate balding.
Birmingham, AlabamaAges 18–55 - NCT06479291Recruiting
HCQ plus TPO-RA for ANA positive ITP
This trial tests if combining two medicines (HCQ and a TPO-RA) can help people with a type of low platelet count called ITP who also have a positive ANA blood test. The goal is to see if this combination works better than standard treatments.
Shanghai, Shanghai MunicipalityAges 15–99 - NCT06479304Recruiting
Hydroxychloroquine plus prednisone for ANA-positive ITP
This study tests whether a combination of hydroxychloroquine (HCQ) and prednisone (a steroid) is safe and effective for treating immune thrombocytopenia (ITP) in people who have a positive ANA blood test. It may be an option for those with low platelets and bleeding risk.
Shanghai, Shanghai MunicipalityAges 15–99 - NCT06479317Recruiting
Combining hydroxychloroquine and dexamethasone for ITP with positive ANA
This trial tests if adding hydroxychloroquine (HCQ) to the steroid dexamethasone (DEX) works better than dexamethasone alone for adults with immune thrombocytopenia (ITP) who have a positive antinuclear antibody (ANA) blood test. The goal is to see if this combination can safely raise platelet counts and reduce bleeding risk.
Shanghai, Shanghai MunicipalityAges 15–75 - NCT07822100Recruiting
Personalized treatment for IgA nephropathy and IgA vasculitis
This trial tests a personalized approach that uses a blood test to help guide targeted therapies for IgA nephropathy and IgA vasculitis. It may help reduce kidney damage and control the disease with fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT07823842Recruiting
Biologics for asthma and COPD
This study looks at how well medicines called biologics work for people with asthma or COPD. Biologics are special shots that target certain parts of the immune system to reduce inflammation. Researchers want to see if these treatments can help control symptoms and prevent flare-ups.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06394063Recruiting
Telitacicept to prevent lupus flares
This trial tests a medicine called Telitacicept to see if it can prevent lupus flares in people whose disease is currently mild or stable. It may be a good option if you want to keep your lupus under control and avoid sudden worsening.
ShanghaiAges 18–70 - NCT07813299Recruiting
Antibiotic rinse in the lungs for bronchiectasis flare-ups
This study tests whether placing a common antibiotic (amikacin) directly into the lungs during a bronchoscopy helps people with bronchiectasis recover faster from sudden flare-ups. Participation involves a bronchoscopy and a lung rinse, which may reduce infection and improve breathing.
Ningbo, ZhejiangAges 18–80 - NCT07811908RecruitingPhase 2
Testing a new malaria treatment for children
This study tests a new malaria treatment for children with mild (uncomplicated) malaria. The goal is to see if the treatment safely and effectively clears the infection.
BanforaAges 2–12 - NCT07816367RecruitingPhase 3
Elismetrep for treating migraine attacks
This study tests an investigational medicine called elismetrep (K-304) for treating migraine attacks quickly. If you have migraines, you take the medicine when a migraine starts and report how well it works.
Glendale, ArizonaAges 18–75 - NCT07809672Recruiting
Stereotactic body radiation therapy for spinal metastases
This trial tests a precise type of radiation therapy for cancer that has spread to the spine. The goal is to see if this treatment is safe and effective in reducing the tumor while protecting your spinal cord and improving your quality of life.
TianjinAges 18 years+ - NCT07814612Recruiting
Guided pacing for heart failure with left bundle branch block
This study tests a new way to place a pacemaker lead inside the heart to help it beat more effectively, aiming to improve heart function and symptoms in people with heart failure and a specific electrical problem (left bundle branch block). If you meet the criteria, this could be an option to discuss with your heart doctor.
Nanchang, JiangxiAges 18–80 - NCT06496412Recruiting
Fecal transplant for brain health in type 1 diabetes
This trial tests whether transplanting healthy bacteria into your gut can improve memory and thinking skills in people with long-term type 1 diabetes. If you have had type 1 diabetes for 10 years or more, this study may help find a new way to protect your brain.
Changsha, HunanAges 18–60 - NCT06497387RecruitingEarly Phase 1
PRG-1801 for stubborn lupus kidney and IgG4 disease
This trial tests a new treatment called PRG-1801 for people with lupus nephritis (kidney inflammation from lupus) or IgG4-related disease that has not improved with standard treatments. The treatment uses your own immune cells to target and calm the disease.
Wuhan, HubeiAges 18 years+ - NCT06244264Recruiting
Using your own blood during spine surgery for lung cancer
This study tests the safety and effectiveness of using your own blood (collected before surgery) during spine surgery for lung cancer that has spread to the backbone. It may help people whose spine is unstable or causing nerve problems.
Guangzhou, GuangdongAges 18–75 - NCT06497361RecruitingEarly Phase 1
PRG-2311 for hard-to-treat lupus nephritis and IgG4 disease
This trial tests a new treatment called PRG-2311 for people with lupus nephritis or IgG4-related disease that has not responded to standard therapies. The treatment uses a type of immune cell therapy (CAR-T) to try to control the disease.
Wuhan, HubeiAges 18 years+ - NCT06141525Recruiting
Remote conditioning for safer heart bypass recovery
This study tests whether a simple, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your arm) can help patients recover better after off-pump heart bypass surgery. The goal is to see if it reduces complications and improves heart function.
Xi'an, ShaanxiAges 18–70
Hear when a new Efficacy and Safety trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.