Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07678177Recruiting
Study of tegoprazan for patients with GERD
This study looks at how well and how safely the drug tegoprazan works for people with gastroesophageal reflux disease (GERD). It may help if you have symptoms like heartburn or acid reflux.
SeoulAges 19 years+ - NCT07680257RecruitingEarly Phase 1
CLDN18.2 CAR T cells for advanced solid tumors
This trial tests a new treatment called CLDN18.2 CAR T cells in people with advanced solid tumors that have a specific marker (CLDN18.2). It aims to see if it is safe and works against cancers that have not responded to standard treatments.
Hefei, AnhuiAges 18–75 - NCT07672561RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This study tests an experimental pill called WD-890 to see if it can help people with moderate to severe plaque psoriasis. The pill is compared to a placebo (a pill with no medicine) to check if it is safe and works well.
Nanjing, JiangsuAges 18–75 - NCT07679412Recruiting
CMV Retinitis Trial: Your Own Cells vs. Resistant Virus
This trial tests a new treatment made from your own immune cells (called LB-DTK-CMV) for a type of CMV eye infection that is not getting better with standard antiviral drugs. The goal is to see if these cells can safely control the infection and improve your vision.
SeoulAges 19 years+ - NCT07678034Recruiting
Long-term safety study of Tipmed shoulder replacement system
This study checks how safe and effective the Tipmed shoulder replacement system is over time. It is for people who already had this specific shoulder implant during surgery.
BalıkesirAges 18 years+ - NCT07675135RecruitingPhase 3
Testing a new narcolepsy drug for excessive daytime sleepiness
This study tests a new medicine, HBS-301, for people with narcolepsy type 1 or type 2 who still have excessive daytime sleepiness. If you take other medications for sleepiness or mood, they must be stable for at least 3 months, and you cannot take some as-needed sleepiness medicines.
Birmingham, AlabamaAges 18 years+ - NCT07673744RecruitingPhase 2
Maintenance treatment for myasthenia gravis after efgartigimod
This trial tests whether a follow-up treatment with ublituximab (given as an infusion) can help myasthenia gravis patients who first received efgartigimod. The goal is to see if it provides lasting control of MG symptoms.
Colorado Springs, ColoradoAges 18 years+ - NCT07673809RecruitingPhase 1/Phase 2
Gene therapy trial for Duchenne muscular dystrophy in young boys
This trial tests a gene therapy called GNR-097 for boys with Duchenne muscular dystrophy (DMD). The therapy aims to help improve muscle function, and the study will check how safe and effective it is.
MinskAges 4–9 - NCT07675811RecruitingPhase 3
Study of a new treatment for cat allergy related eye symptoms
This trial tests an injectable treatment that may help manage eye allergy symptoms caused by cat allergies. It aims to see if the treatment is safe and effective for adults and children, and includes a controlled cat exposure challenge.
Andover, MassachusettsAges 8 years+ - NCT07678866Recruiting
Electric pulse study for type 2 diabetes with poor drug control
This trial tests a new procedure called pulse electric field ablation to see if it can help people with type 2 diabetes whose blood sugar is not well controlled by oral medications. The procedure uses a small device passed through the mouth to the upper intestine.
ShanghaiAges 18–70 - NCT07675850RecruitingPhase 4
Testing computer-guided dosing for general anesthesia
This study tests a computerized dosing system for a sedation medicine called remimazolam during general anesthesia. It is for adults having planned surgery and aims to see if the computer-guided dosing is safe and effective.
Seoul, Jongno-guAges 19–79 - NCT07673302Recruiting
Study of drugs to boost fetal hemoglobin in beta thalassemia
This trial tests if certain drugs can safely increase fetal hemoglobin (a type of hemoglobin that helps carry oxygen) in people with beta thalassemia major. It may offer a new way to manage the condition and reduce the need for transfusions.
Rawalpindi, Punjab ProvinceAges Any age - NCT06439563RecruitingPhase 3
Testing JP-1366 to prevent NSAID-related stomach ulcers
This trial tests a new drug called JP-1366 to see if it can prevent stomach ulcers caused by long-term NSAID use (like ibuprofen or naproxen) for conditions such as arthritis. It may be a good fit if you need to take NSAIDs for at least 24 weeks and have a higher risk of ulcers.
SeoulAges 19 years+ - NCT05503134RecruitingPhase 1/Phase 2
Donor immune cell treatment for relapsed or stubborn AML
This trial tests donated “natural killer (NK) cells,” a type of immune cell, in children and young adults with AML that has come back or did not respond to treatment. It mainly looks at safety and also studies whether the treatment can help control the leukemia.
Columbus, OhioAges 1–24 - NCT06110910Recruiting
Growth hormone study for children with short stature
This study tests if growth hormone can safely help children who are shorter than average for their age and gender. It is for children with certain conditions that cause short stature.
Wuhan, HubeiAges 2 years+ - NCT07668154RecruitingPhase 2
Testing SKB571 for advanced head and neck cancer
This study tests a new drug called SKB571 for people whose head and neck cancer (a type called squamous cell carcinoma) has come back or spread and cannot be surgically removed. The goal is to see if the drug is safe and effective.
ChengduAges 18–75 - NCT07669454RecruitingPhase 3
Nuvastatic® for metastatic colorectal cancer
This trial tests a new capsule (Nuvastatic®) added to standard chemotherapy for people with metastatic colorectal cancer. The goal is to see if it helps shrink tumors and improve well-being.
Visakhapatnam, Andhra PradeshAges 18–65 - NCT07670468RecruitingPhase 1/Phase 2
T-cell therapy for resistant viral infections after transplant or cancer treatment
This trial tests a special T-cell treatment (LB-DTK-MV) for people with virus infections (CMV, BKV, EBV) that did not get better with standard medicines. It is for patients who had a stem cell transplant or certain cancer therapies like CAR-T or bispecific antibodies.
SeoulAges 19 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+ - NCT07670702Enrolling by invitationPhase 3
Long-term safety and effectiveness of TSND-201 for PTSD
This trial checks the long-term safety and how well TSND-201, a study drug, helps people with PTSD. It is for patients who already completed a previous TSND-201 study and did well.
Little Rock, ArkansasAges Any age - NCT07665437RecruitingPhase 3
Long-term safety study of remibrutinib for hidradenitis suppurativa
This study tests the long-term safety and effectiveness of remibrutinib for people with moderate to severe hidradenitis suppurativa (HS) who have already completed a 68-week treatment period in a related study.
Birmingham, AlabamaAges 18–100 - NCT07670884RecruitingPhase 3
Study of HRS9531 for weight loss in overweight or obese adults
This trial tests an oral medication, HRS9531, to help overweight or obese adults lose weight. It may be an option if you have been unable to lose enough weight through diet and exercise alone.
Zhengzhou, HenanAges 18–75 - NCT07664553RecruitingPhase 3
Testing a new diabetes tablet for people on insulin
This trial tests a new once-daily tablet (elecoglipron) against a placebo to see if it can help improve blood sugar control in adults with type 2 diabetes who are already on insulin. It may offer an additional treatment option to help manage your diabetes.
Little Rock, ArkansasAges 18 years+ - NCT06674148RecruitingPhase 2/Phase 3
Qifangfeixian granules for connective tissue disease lung scarring
This trial tests a Chinese herbal medicine called Qifangfeixian granules for people with lung scarring (interstitial lung disease) related to connective tissue diseases (like lupus or scleroderma). It compares the medicine to a placebo to see if it helps improve breathing and lung function.
Wuhan, HubeiAges 18–80
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.