Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07666386Enrolling by invitation
HIV treatment Biktarvy in early pregnancy
This trial checks if the once-daily HIV pill Biktarvy (B/F/TAF) stays safe and works well for women who are newly pregnant (up to 12 weeks). It is for women already taking Biktarvy with a controlled virus load.
Wuhan, HubeiAges 18 years+ - NCT07665424Recruiting
Study of a bone filling device for spine fractures
This trial tests a device called Vessel-X to treat broken vertebrae (spine bones) caused by osteoporosis or injury. It aims to see if the device is safe and helps stabilize the spine.
TaipeiAges 40–95 - NCT07666555RecruitingPhase 2
Culmerciclib rechallenge for HR+ HER2- breast cancer
This trial tests a new drug called Culmerciclib for women with advanced HR-positive, HER2-negative breast cancer that has stopped responding to a CDK4/6 inhibitor with hormone therapy. The goal is to see if giving this drug again can help when other treatments no longer work.
ShanghaiAges 18–75 - NCT07658170Recruiting
Fat graft with platelet-rich fibrin for breast reconstruction after lumpectomy
This trial tests using a patient's own fat plus a special blood product (platelet-rich fibrin) to rebuild the breast right after a lumpectomy for breast cancer. It may help improve healing and appearance for women with early-stage, hormone-sensitive breast cancer.
Saint PetersburgAges 18–69 - NCT07660835RecruitingPhase 2
A study of nemolizumab for babies with eczema
This trial tests a medicine called nemolizumab for babies aged 6 to 23 months with moderate to severe eczema. The goal is to see if it reduces itching and improves skin symptoms.
San Antonio, TexasAges 6 months–1.9 years - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Huntsville, AlabamaAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07663331RecruitingPhase 4
Adalimumab for adults with non-infectious uveitis
This study tests an injection called adalimumab (Tebiovio®) to see if it helps control inflammation in the eyes of adults with non-infectious uveitis. It might be a good option if you are already on steroid pills and looking for another treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07657052Enrolling by invitation
Long-term safety and effectiveness of XH-S003 for PNH
This study tests if the drug XH-S003 is safe and works well over a long period for people with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease. If you've already taken XH-S003 in a past study and your doctor thinks it helped, you may join to keep getting the treatment.
Tianjin, JinanAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
Birmingham, AlabamaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sun City, ArizonaAges 18 years+ - NCT07656753RecruitingEarly Phase 1
Gene therapy trial for RLBP1-related retinal dystrophy
This trial tests an injection (PUMCH-E111) for people with a specific genetic form of inherited retinal dystrophy caused by RLBP1 mutations. It aims to see if the treatment is safe and can help preserve vision.
Beijing, Beijing MunicipalityAges 18–55 - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT07656090Enrolling by invitationEarly Phase 1
Testing IDOV-Immune for advanced solid tumors
This trial tests an investigational drug called IDOV-Immune for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT07662746RecruitingPhase 2
Paclitaxel micelles for advanced head and neck cancer
This trial tests a new form of chemotherapy called paclitaxel polymeric micelles for people with head and neck cancer that has come back or spread. It is for patients who have already tried one line of treatment and may benefit from a different option.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+ - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07650227RecruitingPhase 3
Raphamin for treating acute bronchitis in adults
This study tests whether a medicine called Raphamin can safely and effectively treat acute bronchitis (a chest infection with cough) in adults. Raphamin may help reduce cough and breathing problems in the early stages of this condition.
AramilAges 18–64 - NCT07650084RecruitingPhase 3
Testing BLU-5937 for hard-to-treat chronic cough
This 24-week study tests whether a new medicine called BLU-5937 can help adults whose chronic cough hasn't improved with standard treatments. Chronic cough that lasts a year or longer can seriously affect quality of life, and this trial explores whether this drug might provide relief.
Leshan, SichuanAges 18–80 - NCT07652294Enrolling by invitationPhase 2
Long-term safety of antibodies for IBD maintenance
This trial is testing long-lasting antibodies given alone or in combinations to keep IBD under control over the long term. It's for people who already did well in the initial study and want to continue treatment.
Lancaster, CaliforniaAges 18 years+ - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT07648472RecruitingPhase 1
Safety and efficacy of OVV-01 injection for advanced solid tumors
This study tests a new cancer treatment called OVV-01 that is injected directly into tumors or given through the vein. It's for patients with advanced solid cancers (like melanoma, lung, breast, or colon cancer) who have already tried at least two standard treatments without success.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07654140RecruitingPhase 2
Testing a new drug for uncontrolled high blood pressure
This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.
Beijing, Beijing MunicipalityAges 18–75
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.