Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,825 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07542808RecruitingPhase 2/Phase 3
Stem cell treatment vs. hyaluronic acid for knee arthritis
This study tests whether an injection of stem cells (special cells that can help repair tissue) works better than a standard hyaluronic acid injection for knee osteoarthritis pain. Both treatments are injected into the knee to reduce pain and improve function.
Abu DhabiAges 18 years+ - NCT07459751RecruitingPhase 2/Phase 3
A study of HLX43 alone or with HLX07 vs docetaxel for advanced squamous lung cancer
This trial tests a new drug called HLX43, given alone or with HLX07, against the standard chemo docetaxel for people with a type of advanced lung cancer called squamous non-small cell lung cancer. It's for patients who have already tried and not responded to platinum chemo and immunotherapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07458282Recruiting
Testing a long-lasting numbing medicine for pain after laparoscopic surgery
This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT06959082RecruitingPhase 2
Testing an experimental drug with chemoradiation for head and neck cancer
This trial tests an experimental drug called VS-101 combined with standard radiation and chemotherapy for people with advanced head and neck cancer that hasn't been surgically removed. The goal is to see if adding this drug helps the treatment work better while keeping side effects manageable.
New Haven, ConnecticutAges 18 years+ - NCT07168473RecruitingPhase 3
A study of DW1807 for year-round allergies and asthma
This trial tests a new medicine called DW1807 for people who have both year-round allergies (like dust mites or pet dander) and asthma. It aims to see if it helps control nasal symptoms and is safe to use.
SeoulAges 19 years+ - NCT06718946RecruitingEarly Phase 1
IV IDOV-SAFE for advanced solid tumors: safety and effect study
This trial tests a new drug called IDOV-SAFE given through a vein. It is for people with advanced solid tumors that have not responded to standard treatments. The study aims to see if the drug is safe and if it can help shrink tumors.
ShanghaiAges 18–75 - NCT05640232RecruitingPhase 3
Test medicine CDE100 for severe menstrual cramp pain
This Phase 3 study tests whether CDE100 can reduce menstrual cramp pain in people with primary dysmenorrhea (cramps that are not caused by another medical condition). It also checks how safe the treatment is and how it’s tolerated over time.
Hortolândia, São PauloAges 16–35 - NCT06913725RecruitingPhase 2
Testing FCN-159 for Brain AVM
This trial tests an oral medication called FCN-159 for people with a high-grade brain AVM that has never bled. The goal is to see if it can shrink the AVM or prevent future problems.
Beijing, Beijing MunicipalityAges 18–60 - NCT07441083Recruiting
Shatavari root extract for women's sexual wellness
This trial tests if a herbal supplement called Shatavari can help improve sexual desire and function in women who feel stressed. You would take the supplement daily and report how you feel over several weeks.
San Francisco, CaliforniaAges 20–50 - NCT07559695Recruiting
Menin inhibitor maintenance therapy after stem cell transplant
This study tracks how well a newer drug class (menin inhibitors) works to prevent acute leukemia from coming back after a stem cell transplant. You would be observed for safety and effectiveness if you're already taking one of these drugs.
Suzhou, JiangsuAges 15 years+ - NCT07533786RecruitingPhase 2
New Pain Medicine After Abdominal Surgery
This study tests a new medication called HSK55718 to treat pain after abdominal surgery. If you're having moderate to severe pain within 4 hours of surgery, this trial may help you get relief and contribute to finding better pain treatments.
Changsha, HunanAges 18 years+ - NCT05865028RecruitingPhase 2
Test drug APG-157 for abnormal mouth tissue
This Phase 2 trial studies whether APG-157 can safely improve abnormal cells in the mouth (dysplasia) or early cancer-like changes (carcinoma in situ). You may be eligible if you have a visible, biopsy-proven lesion and can take oral medication while meeting blood and health requirements.
Miami, FloridaAges 18 years+ - NCT06728280Recruiting
DTMS for teens with depression: safety and effectiveness
This trial tests if a new type of brain stimulation called DTMS can safely help adolescents with major depression. It may be an option if you have tried other treatments and are looking for a non-medication approach.
Taiyuan, ShanxiAges 11–23 - NCT07098351Recruiting
A trial for a new itchy skin medicine for people on peritoneal dialysis
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
Guangzhou, GuangdongAges 18–85 - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT06732648RecruitingPhase 2/Phase 3
Testing a new drug for severe brain swelling after a large stroke
This trial tests a new drug called HRS8179 to reduce severe brain swelling after a large stroke. If you have a major stroke on one side of the brain and can start treatment within 10 hours, this study may help prevent dangerous pressure buildup.
Beijing, Beijing MunicipalityAges 18–80 - NCT06665412Recruiting
Radotinib Dose Reduction for Chronic Phase CML
This trial tests if lowering the dose of radotinib is safe and effective for adults newly diagnosed with a certain type of leukemia (chronic phase CML). It may help control the disease while reducing side effects.
Anyang-si, Gyeonnggi-doAges 19 years+ - NCT05837806RecruitingPhase 2
Tislelizumab and disitamab as pre-surgery treatment for HER2 UTUC
This trial tests whether giving tislelizumab plus disitamab vedotin before surgery (neoadjuvant therapy) can improve outcomes for people with HER2-positive, high-risk upper tract urothelial cancer. It also looks at the treatment’s safety and helps doctors learn if certain tumor features predict response.
TianjinAges 18 years+ - NCT06735755RecruitingPhase 1/Phase 2
Study of BEAM-301 for glycogen storage disease type Ia
This study tests an experimental medicine called BEAM-301 for people with a specific form of glycogen storage disease type Ia (GSDIa). The goal is to see if it can help reduce dangerous low blood sugar episodes.
Orange, CaliforniaAges 18 years+ - NCT07381257RecruitingEarly Phase 1
Rifaximin for fatty liver disease
This trial tests if rifaximin, a gut medication, can help reduce liver fat in people with metabolic fatty liver disease. It may be an option if you have at least one metabolic risk factor and a certain amount of liver fat.
ShanghaiAges 18–75 - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07591207Recruiting
Pain relief patch after laparoscopic abdominal surgery
This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–64 - NCT07080385RecruitingPhase 2/Phase 3
Study of encaleret in children with a rare calcium disorder
This trial tests a medicine called encaleret in children with a rare genetic condition that causes low calcium levels. The goal is to see if it safely helps control calcium and reduce symptoms.
New Haven, ConnecticutAges birth–17 years - NCT07142967Recruiting
MR-Linac radiotherapy for prostate cancer that returned after earlier radiation
This trial tests if a special MRI-guided radiotherapy machine (MR-Linac) can safely treat prostate cancer that has come back after previous radiation therapy. It may help men who have limited options and want to avoid more invasive treatments.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,825 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.