Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07385625Recruiting
Studying a new device for severe tricuspid valve leakage
This trial tests a device called the Pivot Bridge System to treat severe leakage of the tricuspid valve (the valve between the right upper and lower heart chambers). The goal is to see if it safely reduces symptoms like swelling and shortness of breath.
Daegu, Dalseo-guAges 18 years+ - NCT07385703RecruitingPhase 3
A trial of LM-302 with tislelizumab for stomach cancer
This trial tests a new drug combination for stomach or gastroesophageal junction cancer that has spread or cannot be removed by surgery. It aims to see if adding LM-302 to standard treatments helps people whose tumors have a specific protein called CLDN18.2.
Hefei, AnhuiAges 18 years+ - NCT06835361RecruitingPhase 2/Phase 3
Comparing two yeast infection treatments for women
This trial tests if a new combination vaginal suppository works better than the standard one for women with yeast infections. It aims to see if adding lactulose to clotrimazole helps clear the infection faster or more completely.
Minsk, Minsk CityAges 18–60 - NCT07387952Recruiting
Fecal transplant with nutrition help for chronic constipation
This trial tests if a fecal microbiota transplant combined with nutritional support can improve chronic constipation that hasn't gotten better with standard treatments. It's a small early study to see if the approach is safe and works.
BeijingAges 18–70 - NCT07382973Recruiting
NTP safety in thyroid surgery: preventing complications
This trial is testing if a technology called NTP (a type of low-temperature plasma) can help prevent complications and improve cancer control when they remove all or part of the thyroid gland. It's for adults having thyroid surgery.
Ocoyoacac, State of MexicoAges 18 years+ - NCT07389083Recruiting
Nose breathing tube for deep sedation lung exam
This study tests a breathing tube put through the nose to deliver oxygen during a lung exam (bronchoscopy) while you are deeply sedated. It aims to find a safer and more comfortable way to keep your oxygen levels up during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07381634RecruitingPhase 2
Testing ondansetron to reduce immunotherapy side effects in liver cancer
This study tests whether adding ondansetron (a common anti-nausea drug) can reduce side effects from immunotherapy in people with liver cancer. If you are starting a specific combination treatment for liver cancer, you may be eligible.
Wenzhou, ZhejiangAges 18–80 - NCT07385573Recruiting
Testing a drug-coated balloon for leg artery blockages
This trial tests a special balloon that releases medication to help keep leg arteries open. It's for people with narrowed or blocked arteries in the leg, either above or below the knee.
AalstAges 18–99 - NCT07381257RecruitingEarly Phase 1
Rifaximin for fatty liver disease
This trial tests if rifaximin, a gut medication, can help reduce liver fat in people with metabolic fatty liver disease. It may be an option if you have at least one metabolic risk factor and a certain amount of liver fat.
ShanghaiAges 18–75 - NCT06492213Recruiting
Combining PRP with Radiofrequency for Face Nerve Pain
This study tests whether adding platelet-rich plasma (a concentrate from your own blood that may help healing) to a standard pulsed radiofrequency procedure reduces pain from infraorbital neuralgia more effectively than radiofrequency alone. It involves two treatments and follow-up for several months.
Beijing, Beijing MunicipalityAges 18–75 - NCT06075433Recruiting
One year of blood thinners after a GENOSS stent for heart disease
This study tests whether taking two blood thinners for one year after getting a special GENOSS stent is safe and works well for people with coronary artery disease, especially if the stent placement was complex. The goal is to prevent blood clots and keep your artery open.
Wŏnju, Gangwon StateAges 19 years+ - NCT06075420Recruiting
Shorter blood thinner use after GENOSS stent in heart disease
This trial tests whether a shorter course of dual antiplatelet therapy (two blood thinners) is safe and effective for people who have received a GENOSS stent for coronary artery disease. It aims to reduce the risk of bleeding while still preventing heart attacks.
Wŏnju, Gangwon StateAges 19 years+ - NCT06238908RecruitingEarly Phase 1
Gene therapy NGGT003 for severe hemophilia A
This early-phase trial tests a new gene therapy called NGGT003 for men with severe hemophilia A. It aims to see if the treatment is safe and can help reduce bleeding episodes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06839768Recruiting
Comparing two procedures for enlarged prostate symptoms
This study compares a new, less invasive laser procedure (MILEP) with the standard surgery (EEP) for treating bothersome urinary symptoms caused by an enlarged prostate. It aims to see if the new approach is just as safe and effective.
MoscowAges 18–85 - NCT06839118RecruitingPhase 3
Botox for headaches after head injury
This trial tests if Botox injections can reduce headache days in people with persistent headaches after a mild head injury. It may help if you have headaches at least 15 days a month.
Glostrup MunicipalityAges 18–80 - NCT05199909RecruitingPhase 2
Testing zanubrutinib for antiphospholipid syndrome with low platelets
This Phase 2 study tests zanubrutinib, a medicine for the immune system, to treat antiphospholipid syndrome when it causes very low platelet counts. It looks at safety and whether it can improve blood clotting problems and low platelets when prior steroid treatment didn’t work well.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05641610RecruitingPhase 1/Phase 2
Study drug for adults with hemophilia B who still bleed
This Phase 1/2 study tests ZS801, a gene-related treatment, to see how safe it is and whether it helps prevent bleeding in adults with hemophilia B. You may be considered if you’ve had frequent bleeds or joint problems and meet several lab and health requirements.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05630651Recruiting
ZS801 for adults with severe hemophilia B
This trial studies ZS801, a gene therapy, in adults with hemophilia B who have very low natural FIX (a clotting protein) and frequent bleeding or joint problems. It aims to see how well it works and whether it is safe, especially by monitoring blood counts, infections, and immune responses.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07376577Recruiting
Sedation for older adults having ERCP
This trial tests a combination of two sedatives (anricofen and ciprofol) for deep sedation in older adults having an ERCP procedure. It aims to see if this combination is safe and effective for patients between 60 and 90 years old with mild to moderate health conditions.
Xinxiang, HenanAges 60–90 - NCT07377422Recruiting
Safer stent placement for carotid artery narrowing
This trial tests a new type of catheter that helps doctors place a stent in the carotid artery through a small tube in your wrist instead of the groin. This could make the procedure safer and more comfortable for you.
BeijingAges 18 years+ - NCT07371572RecruitingPhase 3
Steroid Injection for Hand Osteoarthritis
This study tests whether a steroid injection into the muscle can reduce pain and improve hand function in people with hand osteoarthritis. It is for those whose pain is moderate to severe and hasn't been helped enough by standard pain medications.
Ubbergen, GelderlandAges 16 years+ - NCT07373964RecruitingPhase 2
Study of new drug combo for extensive-stage small-cell lung cancer
This trial tests a new combination of drugs (chidamide, a PD-L1 inhibitor, carboplatin, and etoposide) as the first treatment for people with extensive-stage small-cell lung cancer. The goal is to see if this combination works better than standard treatments.
Shenyang, LiaoningAges 18–75 - NCT07371247Enrolling by invitationEarly Phase 1
Adjuvant treatment guided by ctDNA after chemoradiation for esophageal cancer
This trial tests whether adjusting treatment based on a blood test (ctDNA) after standard chemoradiation can improve outcomes for patients with advanced esophageal squamous cell carcinoma. It aims to find a more personalized approach to prevent cancer recurrence.
Nanjing, JiangsuAges 18–80 - NCT07378046Recruiting
Baclofen for shingles pain: a safety and effectiveness study
This study tests whether the muscle relaxant baclofen can safely reduce shingles pain. It is for adults with moderate to severe pain who have not tried this drug before.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.